dc.contributor.author |
Toye, Philip G.
|
|
dc.contributor.author |
Batten, C.A.
|
|
dc.contributor.author |
Kiara, Henry
|
|
dc.contributor.author |
Henstock, M.R.
|
|
dc.contributor.author |
Edwards, L.
|
|
dc.contributor.author |
Thumbi, Samuel Mwangi
|
|
dc.contributor.author |
Poole, Elizabeth Jane
|
|
dc.contributor.author |
Handel, Ian Graham
|
|
dc.contributor.author |
Bronsvoort, Barend Mark de Clare
|
|
dc.contributor.author |
Hanotte, Olivier
|
|
dc.contributor.author |
Coetzer, Jacobus A.W.
|
|
dc.contributor.author |
Woolhouse, Mark E.J.
|
|
dc.contributor.author |
Oura, C.A.L.
|
|
dc.date.accessioned |
2013-07-12T07:52:54Z |
|
dc.date.available |
2013-07-12T07:52:54Z |
|
dc.date.issued |
2013-03 |
|
dc.description.abstract |
The presence of bluetongue virus (BTV) and Epizootic Haemorrhagic Disease virus (EHDV) in indigenous
calves in western Kenya was investigated. Serum was analysed for BTV and EHDV antibodies. The population
seroprevalences for BTV and EHDV for calves at 51 weeks of age were estimated to be 0.942 (95% CI
0.902–0.970) and 0.637 (95% CI 0.562–0.710), respectively, indicating high levels of circulating BTV and
EHDV. The odds ratio of being positive for BTV if EHDV positive was estimated to be 2.57 (95% CI 1.37–
4.76). When 99 calves were tested for BTV and EHDV RNA by real-time RT-PCR, 88.9% and 63.6% were
positive, respectively. Comparison of the serology and real-time RT-PCR results revealed an unexpectedly
large number of calves that were negative by serology but positive by real-time RT-PCR for EHDV. Eight
samples positive for BTV RNA were serotyped using 24 serotype-specific real-time RT-PCR assays. Nine
BTV serotypes were detected, indicating that the cattle were infected with a heterogeneous population
of BTVs. The results show that BTV and EHDV are highly prevalent, with cattle being infected from an
early age. |
en |
dc.description.librarian |
hb2013 |
en |
dc.description.librarian |
ab2013 |
|
dc.description.sponsorship |
The Wellcome Trust (Project 079445) |
en |
dc.description.uri |
http://www.elsevier.com/locate/rvsc |
en |
dc.identifier.citation |
Toye, PG ... et al 2013, 'Bluetongue and Epizootic Haemorrhagic Disease virus in local breeds of cattle in Kenya', Research in Veterinary Science, vol. 94, no. 3, pp. 769-773. |
en |
dc.identifier.issn |
0034-5288 (print) |
|
dc.identifier.issn |
1532-2661 (online) |
|
dc.identifier.other |
10.1016/j.rvsc.2012.11.001 |
|
dc.identifier.uri |
http://hdl.handle.net/2263/21915 |
|
dc.language.iso |
en |
en |
dc.publisher |
Elsevier |
en |
dc.relation.requires |
Adobe Acrobat Reader |
en |
dc.rights |
© 2012 Elsevier Ltd. All rights reserved. Notice : this is the author’s version of a work that was accepted for publication in Research in Veterinary Science.Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Research in Veterinary Science, vol.94, no. 3, 2013, doi.: 10.1016/j.rvsc.2012.11.001. |
en |
dc.subject |
Kenya |
en |
dc.subject |
Prevalence |
en |
dc.subject |
Bluetongue virus |
en |
dc.subject |
Epizootic haemorrhagic disease virus |
en |
dc.subject |
EHDV |
en_ZA |
dc.subject.lcsh |
Cattle -- Diseases |
en |
dc.subject.lcsh |
Communicable diseases in animals -- Kenya |
en |
dc.subject.lcsh |
Bluetongue -- Kenya |
en |
dc.subject.lcsh |
Bluetongue virus -- Kenya |
en |
dc.title |
Bluetongue and epizootic haemorrhagic disease virus in local breeds of cattle in Kenya |
en |
dc.type |
Postprint Article |
en |