Phased implementation of screening for cryptococcal disease in South Africa
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Date
Authors
Govender, N.P. (Nelesh)
Chetty, V.
Roy, M.
Chiller, T.
Oladoyinbo, S.
Maotoe, T.
Stevens, W.S.
Pinini, Z.
Spencer, D.
Venter, Willem Daniel Francois
Journal Title
Journal ISSN
Volume Title
Publisher
Health and Medical Publishing Group
Abstract
Cryptococcus neoformans is the most common cause of laboratoryconfirmed
meningitis in South Africa.1 Despite the increased coverage of
antiretroviral treatment (ART), the country’s incidence of cryptococcal
meningitis remains high, and in routine care settings, the disease has a
case-fatality ratio of >50% at 12 weeks post-diagnosis.2-4 Screening and
pre-emptive antifungal treatment is desirable to prevent the development of
cryptococcal meningitis and associated deaths.
Description
Keywords
Cryptococcal disease, Cryptococcus neoformans, Meningitis in South Africa
Sustainable Development Goals
Citation
Govender, NP, Chetty, V, Roy, M, Chiller, T, Oladoyinbo, S, Maotoe, T, Stevens, WS, Pinini, Z, Spencer, D, Venter, WDF, Jassat, W, Cameron, D, Meintjes, G, Mbengashe, T & Pillay, Y 2012, 'Phased implementation of screening for cryptococcal disease in South Africa', South African Medical Journal, vol. 102, no. 12, pp. 914-917.