Phased implementation of screening for cryptococcal disease in South Africa

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Authors

Govender, N.P. (Nelesh)
Chetty, V.
Roy, M.
Chiller, T.
Oladoyinbo, S.
Maotoe, T.
Stevens, W.S.
Pinini, Z.
Spencer, D.
Venter, Willem Daniel Francois

Journal Title

Journal ISSN

Volume Title

Publisher

Health and Medical Publishing Group

Abstract

Cryptococcus neoformans is the most common cause of laboratoryconfirmed meningitis in South Africa.1 Despite the increased coverage of antiretroviral treatment (ART), the country’s incidence of cryptococcal meningitis remains high, and in routine care settings, the disease has a case-fatality ratio of >50% at 12 weeks post-diagnosis.2-4 Screening and pre-emptive antifungal treatment is desirable to prevent the development of cryptococcal meningitis and associated deaths.

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Keywords

Cryptococcal disease, Cryptococcus neoformans, Meningitis in South Africa

Sustainable Development Goals

Citation

Govender, NP, Chetty, V, Roy, M, Chiller, T, Oladoyinbo, S, Maotoe, T, Stevens, WS, Pinini, Z, Spencer, D, Venter, WDF, Jassat, W, Cameron, D, Meintjes, G, Mbengashe, T & Pillay, Y 2012, 'Phased implementation of screening for cryptococcal disease in South Africa', South African Medical Journal, vol. 102, no. 12, pp. 914-917.