dc.contributor.author |
Meintjes, Graeme
|
|
dc.contributor.author |
Maartens, Gary
|
|
dc.contributor.author |
Boulle, Andrew
|
|
dc.contributor.author |
Conradie, Francesca
|
|
dc.contributor.author |
Goemaere, Eric
|
|
dc.contributor.author |
Hefer, Eric
|
|
dc.contributor.author |
Johnson, Dave
|
|
dc.contributor.author |
Mathe, Moeketsi
|
|
dc.contributor.author |
Moosa, Yunus
|
|
dc.contributor.author |
Osih, Regina
|
|
dc.contributor.author |
Rossouw, Theresa M.
|
|
dc.contributor.author |
Van Cutsem, Gilles
|
|
dc.contributor.author |
Variava, Ebrahim
|
|
dc.contributor.author |
Venter, Francois
|
|
dc.contributor.author |
Spencer, Dave
|
|
dc.date.accessioned |
2013-04-19T08:57:41Z |
|
dc.date.available |
2013-04-19T08:57:41Z |
|
dc.date.issued |
2012-09 |
|
dc.description |
Specific recommendations provided here are intended only as a guide to clinical therapy, based
on expert consensus and best current evidence. Treatment decisions for patients should be made by their
responsible clinicians, with due consideration for individual circumstances. The most current version of this
document should always be consulted. |
en_US |
dc.description |
All expert panel members have completed and
submitted conflict of interest disclosure forms. Disclosure information
represents the previous 3 years (updated 17 August 2012) and includes
relationships with pharmaceutical companies and medical aids: Dr
Francesca Conradie has received support from Abbott to attend
conferences, and research support from Tibotec. She has also received
honoraria for speaking engagements from Abbott and MSD. Dr Hefer
has received support to attend conferences from Abbott, Adcock Ingram,
Aspen and MSD. He owns shares in Lifecell and has received honoraria
for speaking engagements from Abbott, Aspen and MSD. Dr Johnson
has received research support from Bristol Myers Squibb (BMS), MSD,
Tibotec and Schering-Plough. He has also received honoraria for speaking
engagements from Abbott. Professor Graeme Meintjes has received
honoraria for speaking engagements from Sanofi Aventis and serves
as a consultant for Aid for AIDS. Professor Yunus Moosa has received
support to attend conferences from Abbott and honoraria for speaking at
conferences/seminars from Abbott, Aspen, MSD and Pfizer. Dr Theresa
Rossouw serves as a consultant for Discovery Health. Dr Ebrahim Variava
receives support for clinical trials from Outsuka. Professor Francois
Venter has received support to attend conferences from Adcock Ingram
and MSD; honoraria for speaking engagements from MSD; and has
served as a consultant for Abbott, Johnson and Johnson and Tibotec. Dr
Eric Goemaere, Professor Gary Maartens, Dr Moeketsi Mathe, Dr Regina
Osih and Dr Gilles Van Custem report no conflicts of interest. |
en_US |
dc.description.abstract |
These guidelines are intended as an update to those published
in the Southern African Journal of HIV Medicine in January
2008. Since the release of the previous guidelines, the scaleup
of antiretroviral therapy (ART) in Southern Africa has
continued to grow. Cohort studies from the region show
excellent clinical outcomes; however, ART is still being
started late (in advanced disease), resulting in relatively
high early mortality rates. New data on antiretroviral (ARV)
tolerability in the region and several new ARV drugs have
become available. Although currently few in number, some
patients in the region are failing protease inhibitor (PI)-
based second-line regimens. To address this, guidelines on
third-line (or ‘salvage’) therapy have been expanded. |
en_US |
dc.description.librarian |
am2013 |
en_US |
dc.description.sponsorship |
This work is supported and funded by the
Southern African HIV Clinicians Society through an educational grant
from Atlantic Philanthropies. |
en_US |
dc.description.uri |
www.sajhivmed.org.za |
en_US |
dc.format.extent |
20 pages |
en_US |
dc.format.medium |
PDF |
en_US |
dc.identifier.citation |
Meintjes, G, Maartens, G, Boulle, A, Conradie, F, Goemaere, E, Hefer, E, Johnson, D, Mathe, M, Moosa, Y, Osih, R, Rossouw, T, Van Cutsem, G, Variava, E, Venter, F & Spencer, D 2012, 'Guidelines for antiretroviral therapy in adults by the Southern African HIV clinicians society', Southern African Journal of HIV Medicine, vol. 13, no. 3, pp. 114-133. |
en_US |
dc.identifier.issn |
1608-9693 (print) |
|
dc.identifier.issn |
2078-6751 (online) |
|
dc.identifier.other |
10.7196/SAJHIVMED.862 |
|
dc.identifier.uri |
http://hdl.handle.net/2263/21334 |
|
dc.language.iso |
en |
en_US |
dc.publisher |
Health and Medical Publishing Group |
en_US |
dc.rights |
Health and Medical Publishing Group |
en_US |
dc.subject |
Antiretroviral therapy (ART) |
en_US |
dc.subject |
Clinical therapy |
en_US |
dc.title |
Guidelines for antiretroviral therapy in adults by the Southern African HIV clinicians society |
en_US |
dc.type |
Article |
en_US |