dc.contributor.author |
Channa, Kalavati R.
|
|
dc.contributor.author |
Rollin, Halina B.
|
|
dc.contributor.author |
Wilson, Kerry S.
|
|
dc.contributor.author |
Nost, Therese H.
|
|
dc.contributor.author |
Odland, Jon Oyvind
|
|
dc.contributor.author |
Naik, Inakshi
|
|
dc.contributor.author |
Sandanger, Torkjel M.
|
|
dc.date.accessioned |
2013-02-05T13:07:29Z |
|
dc.date.available |
2013-11-30T00:20:04Z |
|
dc.date.issued |
2012-11 |
|
dc.description |
Part of this work was presented at the Environmental Health
Conference 2011 – Resetting our Priorities, Salvador, Brazil, 6–9
February 2011. |
en_US |
dc.description.abstract |
Exposure to pesticides places pregnant women and the developing foetus at the highest risk. The objective of this study is to obtain an exposure assessment by investigating levels of pesticides in blood
plasma of delivering women. We report on the concentrations of a, b, g HCH, endosulfan, HCB and the pyrethroids: cis-permethrin, cyfluthrin, cypermethrin and deltamethrin found in the maternal blood plasma of delivering women (n ¼ 241) in three coastal sites of KwaZulu Natal. g-HCH and endosulfan 1 and 2 were the most dominant pesticides in all three sites. Significantly, higher levels of g-HCH and endosulfan were found in site 3 (vicinity of Empangeni) compared to the other two sites (p < 0.05). The GMlevels for g-HCH, endosulfan 1 and 2 were 956, 141 and 21 ng g 1 lipids in site 3, respectively. The pyrethroid pesticides, HCB, a-HCH and b-HCH were detected in less than 31% of the samples in all
sites. g-HCH correlated positively and strongly to both endosulfan 1 and 2 (r > 0.47), indicating a common source of exposure. The high levels of g-HCH and endosulfan in maternal plasma samples in site 3 indicate the current and on-going exposure, which is of great concern for reproductive health and prenatal exposure. |
en_US |
dc.description.librarian |
am2013 |
en_US |
dc.description.librarian |
ay2013 |
en |
dc.description.sponsorship |
The Research Council of Norway and
the National Research Foundation, South Africa (Grant 64528),
the Arctic Monitoring and Assessment Programme (AMAP), the
Royal Norwegian Ministry for Foreign Affairs and the SA
Medical Research Council. |
en_US |
dc.description.uri |
http://www.rsc.org/jem |
en_US |
dc.identifier.citation |
Channa, KR, Rollin, HB, Wilson, KS Nost, TH, Odland, JO, Naik, I & Sandanger, TM 2012, 'Regional variation in pesticide concentrations in plasma of delivering women residing in rural Indian Ocean coastal regions of South Africa', Journal of Environmental Monitoring, vol. 14, no. 11, pp. 2952-2960. |
en_US |
dc.identifier.issn |
1464-0325 (print) |
|
dc.identifier.issn |
1464-0333 (online) |
|
dc.identifier.other |
10.1039/c2em30264k |
|
dc.identifier.uri |
http://hdl.handle.net/2263/20946 |
|
dc.language.iso |
en |
en_US |
dc.publisher |
Royal Society of Chemistry |
en_US |
dc.rights |
© Royal Society of Chemistry |
en_US |
dc.subject |
Pesticides |
en_US |
dc.subject |
Pregnant women |
en_US |
dc.subject |
Blood plasma |
en_US |
dc.subject.lcsh |
Pesticides -- Adverse effects |
en |
dc.subject.lcsh |
Pesticides -- Toxicology |
en |
dc.title |
Regional variation in pesticide concentrations in plasma of delivering women residing in rural Indian Ocean coastal regions of South Africa |
en_US |
dc.type |
Article |
en_US |