Global stability analysis of SEIR model with Holling type II incidence function

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dc.contributor.author Safi, Mohammad A.
dc.contributor.author Garba, Salisu M.
dc.contributor.editor Waniewski, Jacek
dc.date.accessioned 2012-12-13T06:23:43Z
dc.date.available 2012-12-13T06:23:43Z
dc.date.issued 2012
dc.description.abstract A deterministicmodel for the transmission dynamics of a communicable disease is developed and rigorously analysed. Themodel, consisting of five mutually exclusive compartments representing the human dynamics, has a globally asymptotically stable diseasefree equilibrium (DFE) whenever a certain epidemiological threshold, known as the basic reproduction number (R0), is less than unity; in such a case the endemic equilibrium does not exist. On the other hand, when the reproduction number is greater than unity, it is shown, using nonlinear Lyapunov function of Goh-Volterra type, in conjunction with the LaSalle’s invariance principle, that the unique endemic equilibrium of the model is globally asymptotically stable under certain conditions. Furthermore, the disease is shown to be uniformly persistent whenever R0 > 1. en_US
dc.description.sponsorship The University of Pretoria Research and Development Project (RDP) en_US
dc.description.uri http://www.hindawi.com/journals/cmmm/contents/2/ en_US
dc.identifier.citation Safi, MA & Garba, SM 2012, 'Global stability analysis of SEIR model with Holling type II incidence function', Computational and Mathematical Methods in Medicine, vol. 2012, no. Article ID 826052, pp. 1-8. en_US
dc.identifier.issn 1748-670X (print)
dc.identifier.issn 1748-9718 (online)
dc.identifier.other 10.1155/2012/826052
dc.identifier.uri http://hdl.handle.net/2263/20804
dc.language.iso en en_US
dc.publisher Hindawi Publishing Corporation en_US
dc.rights © 2012 M. A. Safi and S. M. Garba. This is an open access article distributed under the Creative Commons Attribution License. en_US
dc.subject SEIR model en_US
dc.subject Holling type II incidence function en_US
dc.title Global stability analysis of SEIR model with Holling type II incidence function en_US
dc.type Article en_US


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