Seroconversion in captive African wild dogs (Lycaon pictus) following administration of a chicken head bait/SAG-2 oral rabies vaccine combination

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dc.contributor.author Liebenberg, A.
dc.contributor.author Du Toit, J.T.
dc.contributor.editor Boomker, Jacob Diederik Frederik
dc.contributor.upauthor Knobel, Darryn Leslie
dc.date.accessioned 2012-12-12T06:45:56Z
dc.date.available 2012-12-12T06:45:56Z
dc.date.created 2011
dc.date.issued 2003
dc.description The articles have been scanned with a HP Scanjet 8300; 600dpi, saved in TIFF format. Adobe Acrobat v.9 was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. en_US
dc.description.abstract This study determined the proportion of captive juvenile and adult African wild dogs (Lycaon pictus) that developed protective titres of rabies neutralising antibodies following ingestion of a chicken head bait/SAG-2 oral rabies vaccine combination. A single chicken head containing 1.8 ml of SAG-2 vaccine (10⁸˙⁰ TCID₅₀/ml) in a plastic blister was fed to each of eight adult and three juvenile wild dogs. Bait ingestion resulted in a significant rise in serum neutralising antibody titres. Overall seroconversion rate was eight out of 11 (72.7 %), and all the puppies and five out of eight (62.5 %) adults showed potentially protective levels of antibodies on day 31. The mean post-vaccination neutralising antibody titre was within the range reported to be protective against challenge with virulent rabies virus in other species. en_US
dc.description.sponsorship National Research Foundation. University of Pretoria. Honorary Rangers Society of South Africa. en_US
dc.identifier.citation Knobel, DL, Liebenberg, A & Du Toit, JT 2003, 'Seroconversion in captive African wild dogs (Lycaon pictus) following administration of a chicken head bait/SAG-2 oral rabies vaccine combination'. Onderstepoort Journal of Veterinary Research, vol. 70, no. 1, pp. 73-77. en_US
dc.identifier.issn 0030-2465
dc.identifier.other 6602518021
dc.identifier.other O-7057-2014
dc.identifier.other 0000-0002-0425-3799
dc.identifier.uri http://hdl.handle.net/2263/20692
dc.language.iso en en_US
dc.publisher Published jointly by the Agricultural Research Council, ARC-Onderstepoort Veterinary Institute and the Faculty of Veterinary Science, University of Pretoria. en_US
dc.rights © ARC-Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). © University of Pretoria. Dept of Library Services (digital). en_US
dc.subject Veterinary medicine en_US
dc.subject Lycaon pictus en_US
dc.subject Oral vaccination en_US
dc.subject Rabies en_US
dc.subject SAG-2 en_US
dc.subject.lcsh Veterinary medicine -- South Africa
dc.title Seroconversion in captive African wild dogs (Lycaon pictus) following administration of a chicken head bait/SAG-2 oral rabies vaccine combination en_US
dc.type Article en_US


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