The heart remembers : observations of cardiac memory in the Dorper sheep heart

Show simple item record Bekker, P.A .
dc.contributor.editor Boomker, Jacob Diederik Frederik
dc.contributor.upauthor Webb, E.C. (Edward Cottington)
dc.contributor.upauthor Ker, James A. 2012-12-12T06:45:09Z 2012-12-12T06:45:09Z 2011 2003
dc.description The articles have been scanned with a HP Scanjet 8300; 600dpi, saved in TIFF format. Adobe Acrobat v.9 was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. en_US
dc.description.abstract Memory is a property common to a diverse range of tissues. Cardiac memory has been demonstrated in the human, dog, rat and rabbit. This is a peculiar phenomenon reflected in the T wave of the electrocardiogram. The heart is able to remember periods of alterations in the sequence of ventricular activation and once there is a return to a normal sequence of ventricular activation the T waves may manifest memory. Cardiac memory is noted when the T wave during normal ventricular activation retains the vector of the previous abnormal QRS complex, caused by a period of altered ventricular activation. Possible mechanisms of memory in the heart are alterations of the transient outward potassium current (Iᵼ₀) in ventricular myocytes and new protein synthesis inside myocytes. These two mechanisms operate in short- and long-term cardiac memory respectively. Currently, it is unknown whether memory may have adverse structural consequences in the heart. We were able to demonstrate memory in the hearts of Dorper wethers and this is the first report of cardiac memory in Dorper sheep. en_US
dc.identifier.citation Ker, J, Webb, EC, Ker, JA & Bekker, PA 2003, 'The heart remembers: observations of cardiac memory in the Dorper sheep heart'. Onderstepoort Journal of Veterinary Research, vol. 70, no. 4, pp. 299-305. en_US
dc.identifier.issn 0030-2465
dc.language.iso en en_US
dc.publisher Pretoria : Agricultural Research Council, ARC-Onderstepoort Veterinary Institute and the University of Pretoria, Faculty of Veterinary Science en_US
dc.rights © ARC-Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). © University of Pretoria. Dept of Library Services (digital). en_US
dc.subject Veterinary medicine en_US
dc.subject Cardiac memory en_US
dc.subject Dorper sheep en_US
dc.subject Electrocardiograph en_US
dc.subject.lcsh Veterinary medicine -- South Africa
dc.title The heart remembers : observations of cardiac memory in the Dorper sheep heart en_US
dc.type Article en_US
dc.type Text en_ZA

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