Modeling and verification of melanin concentration on human skin type

Show simple item record Karsten, Aletta Elizabeth Smit, Jacoba Elizabeth 2012-12-06T09:02:25Z 2013-03-31T00:20:04Z 2012-03
dc.description.abstract Lasers are used in the minimalistic or non-invasive diagnosis and treatment of skin disorders. Less laser light reaches the deeper skin layers in dark skin types, due to its higher epidermal melanin concentration compared to lighter skin. Laser-tissue interaction modelling software can correct for this by adapting the dose applied to the skin. This necessitates an easy and reliable method to determine the skin’s type. Non-invasive measurement of the skin’s melanin content is the best method. However, access to samples of all skin types is often limited and skin-like phantoms are used instead. This study’s objective is to compare experimentally measured absorption features of liquid skin-like phantoms representing Skin Types I to VI with a realistic skin computational model component of ASAP®. Sample UV13 VIS transmittance spectra were measured from 370 to 900 nm and compared to simulated results from ASAP® using the same optical parameters. Results indicated non-monotonic absorption features towards shorter wavelengths, which may allow for more accurate ways of determining melanin concentration and expected absorption through the epidermal layer. This suggests possible use in representing optical characteristics of real skin. However, a more comprehensive model and phantoms are necessary to account for the effects of sun exposure. en_US
dc.description.sponsorship CSIR Parliamentary Grants en_US
dc.description.uri en_US
dc.identifier.citation Karsten, AE & Smit, JE 2012, 'Modeling and verification of melanin concentration on human skin type', Photochemistry and Photobiology, vol. 88, no. 2, pp. 469-474. en_US
dc.identifier.issn 0031-8655 (print)
dc.identifier.issn 1751-1097 (online)
dc.identifier.other 10.1111/j.1751-1097.2011.01044.x.
dc.language.iso en en_US
dc.publisher Wiley-Blackwell en_US
dc.rights © 2011 CSIR and The American Society of Photobiology. The definite version is available at en_US
dc.subject Human skin type en_US
dc.subject Modeling and verification en_US
dc.title Modeling and verification of melanin concentration on human skin type en_US
dc.type Postprint Article en_US

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