Immunocytochemical methods were employed to demonstrate endocrine cells, containing peptides and
serotonin, in the gut of the impala. Cells immunoreactive to serotonin, somatostatin, gastrin, cholecystokinin,
glucagon, neurotensin, secretin, glucose-dependant insulinotropic peptide and motilin were detected.
Antisera raised to substance P and pancreatic polypeptide failed to stain any cells. The distribution
of these peptide-containing cells is more in line with the situation in sheep than other ruminants. In
contrast, the distribution and abundance of serotonin cells in the gut of the impala parallels the situation
seen in game herbivores.
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