A case of unexplained cyanosis

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Authors

Soma, Prashilla
Ellemdin, Shiraz

Journal Title

Journal ISSN

Volume Title

Publisher

Clinics Cardiv

Abstract

It is now clear that hepatopulmonary syndrome (HPS) may occur and contribute significantly to gas exchange abnormalities in the setting of other cardiopulmonary abnormalities. Since there is no gold-standard diagnostic test for HPS, diagnosis rests on documenting arterial oxygenation abnormalities resulting from intrapulmonary vasodilatation in the setting of liver disease. Retrospective studies suggest that many patients with HPS develop progressive intrapulmonary vasodilatation over time and that mortality is significant. This case highlights the clinical value in investigating for HPS and right-to-left shunts when confronted with a patient presenting with unexplained hypoxia in combination with platypnoea and/or orthodeoxia.

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Keywords

Cyanosis, Hepatopulmonary syndrome, Hypoxaemia

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Citation

Soma, P & Ellemdin, S 2012, 'A case of unexplained cyanosis', Cardiovascular Journal of Africa, vol. 23, no. 8, pp. e11-e12.