Fertility in rats immunized with steroid-free bovine follicular fluid

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dc.contributor.author Sewani-Rusike, C.R.
dc.contributor.author Dakwa, C.
dc.contributor.editor Verwoerd, Daniel Wynand
dc.date.accessioned 2012-09-27T10:38:16Z
dc.date.available 2012-09-27T10:38:16Z
dc.date.created 2012
dc.date.issued 2000
dc.description The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat v.9 was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. en
dc.description.abstract Inhibin is a gonadal hormone that inhibits the release of follicle stimulating hormone (FSH) from the anterior pituitary gland. The objective of this study was to determine whether active immunization of male and female rats against inhibin rich, steroid-free bovine follicular fluid would increase inhibin antibody titre, onset of female puberty, pregnancy rate, litter size, testis weights, testosterone concentration and serum FSH. Immunization of rats with steroid free bovine follicular fluid stimulated production of anti-inhibin antibodies that immunoneutralized endogenous inhibins and increased levels of circulating FSH in immunized males. Inhibin immunoneutralization resulted in early vaginal opening in immunized females compared with controls and pregnancy rates were increased when immunized female rats were mated with immunized males. However, serum testosterone, testis weights and potential litter size remained unchanged. We conclude that methods to immunoneutralize inhibin may have merit as therapeutic procedures to enhance reproductive performance in domestic animals. en
dc.description.librarian mn2012 en
dc.description.sponsorship University of Zimbabwe Research Board. en
dc.identifier.citation Sewani-Rusike, CR & Dakwa, C 2000, 'Fertility in rats immunized with steroid-free bovine follicular fluid’. Onderstepoort Journal of Veterinary Research, vol. 67, no. 4, pp. 257-262 en
dc.identifier.issn 0330-2465
dc.identifier.uri http://hdl.handle.net/2263/19904
dc.language en
dc.publisher Published by the Agricultural Research Council, Onderstepoort Veterinary Institute . en
dc.rights © ARC-Onderstepoort (original). © University of Pretoria. Dept of Library Services (digital). en
dc.subject Veterinary medicine en
dc.subject Fertility en
dc.subject FSH en
dc.subject Immunoneutralization en
dc.subject Inhibin en
dc.subject.lcsh Veterinary medicine -- South Africa
dc.subject.lcsh Veterinary medicine -- Research en
dc.title Fertility in rats immunized with steroid-free bovine follicular fluid en
dc.type Article en


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