The importance of the aggregation of ticks on small mammal hosts for the establishment and persistence of tick-borne pathogens : an investigation using the R0 model

Show simple item record

dc.contributor.author Harrison, Alan
dc.contributor.author Bennett, Nigel C., 1961-
dc.date.accessioned 2012-09-18T10:30:55Z
dc.date.available 2013-04-29T00:20:03Z
dc.date.issued 2012
dc.description.abstract Aggregation of parasites amongst hosts is important for the epidemiology of vector-borne diseases because hosts that support the majority of the vector population are responsible for the majority of pathogen transmission. Ixodes ricinus ticks transmit numerous pathogens of medical importance including Borrelia burgdorferi s.l. and tick-borne encephalitis virus. One transmission route involved is ‘co-feeding transmission’, where larvae become infected via feeding alongside infected nymphs. The aggregation of ticks on hosts leads to an increase in the number of larvae feeding alongside nymphs, increasing the transmission potential via this route. The basic reproduction number, R0, can be used to identify whether a pathogen will become established if introduced. In the current study we use previously published tick, and pathogen, specific data to parameterize an R0 model to investigate how the degree of aggregation of ticks on hosts affects pathogen persistence. The coincident aggregated distribution permitted the establishment of tick-borne encephalitis virus but did not influence whether B. burgdorferi s.l. became established. The relationship between the k-exponent of the negative binomial distribution and R0 was also defined. Therefore, the degree of aggregation of ticks on small mammal hosts has important implications for the risk to human health in a given area. en
dc.description.librarian ab2012 en
dc.description.sponsorship A University of Pretoria Postdoctoral Fellowship awarded to A. Harrison and the DSTNRF South African Research Chair of Behavioural Ecology and Physiology awarded to N.C. Bennett. en
dc.description.uri http://journals.cambridge.org/action/displayJournal?jid=par en
dc.identifier.citation Harrison, A & Bennett, NC 2012, 'The importance of the aggregation of ticks on small mammal hosts for the establishment and persistence of tick-borne pathogens : an investigation using the R0 model', Parasitology, pp. 1-9. en
dc.identifier.issn 0031-1820 (print)
dc.identifier.issn 1469-8161 (online)
dc.identifier.other 10.1017/S0031182012000893
dc.identifier.uri http://hdl.handle.net/2263/19798
dc.language.iso en en
dc.publisher Cambridge University Press en
dc.rights © Cambridge University Press 2012 en
dc.subject Vector-borne diseases en
dc.subject Aggregation en
dc.subject Transmission en
dc.subject Ixodes ricinus en
dc.subject Borrelia burgdorferi s.l. en
dc.subject Epidemiology en
dc.subject.lcsh Ticks en
dc.subject.lcsh Tick-borne diseases in animals en
dc.subject.lcsh Castor bean tick en
dc.title The importance of the aggregation of ticks on small mammal hosts for the establishment and persistence of tick-borne pathogens : an investigation using the R0 model en
dc.type Article en


Files in this item

This item appears in the following Collection(s)

Show simple item record