Chronic ulcerative stomatitis : a distinct clinical entity?

Show simple item record Fourie, Jeanine Van Heerden, W.F.P. (Willem Francois Petrus), 1958- McEachen, Stuart C. Van Zyl, Andre W. 2012-05-07T14:32:56Z 2012-05-07T14:32:56Z 2011-04
dc.description.abstract Chronic ulcerative stomatitis (CUS) is a mucocutaneous disorder which is characterised by persistent oral mucosal ulceration. The clinical appearance is often reminiscent of oral lichen planus (OLP) leading to erroneous diagnoses. The immune mediated inhibition of the CUS protein (CUSP) is implicated in the pathogenesis of CUS. CUSP acts as an anti-apoptotic protein and when its action is prevented it may result in significant epithelial injury. The objective or this article is to present the first documented case of CUS in South Africa, with relevant reference to current international literature. CUS should be considered in patients previously diagnosed with OLP but who are unresponsive to glucocorticosteroid therapy. The condition can be successfully managed using hydroxychloroquine. en_US
dc.description.uri en_US
dc.identifier.citation Fourie, J, Van Heerden, WFP, McEachen & Van Zyl, A 2011, 'Chronic ulcerative stomatitis : a distinct clinical entity?', South African Dental Journal, vol. 66, no. 3, pp. 119-121. en_US
dc.identifier.issn 1029-4864
dc.language.iso en en_US
dc.publisher South African Dental Association en_US
dc.rights South African Dental Association en_US
dc.subject Chronic ulcerative stomatitis (CUS) en_US
dc.subject Oral mucosal ulceration en_US
dc.subject Oral lichen planus (OLP) en_US
dc.title Chronic ulcerative stomatitis : a distinct clinical entity? en_US
dc.type Article en_US

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