Lymph node biopsy : some aspects revisited

Abstract

Lymph node biopsy, if performed correctly, is likely to yield an optimal diagnostic result. However, in view of the invasive nature of the procedure, biopsy should only be undertaken in patients with a definitive clinical indication. Less invasive investigations, such as full blood count and serology, and fine needle aspiration (FNA), may indeed provide a conclusive diagnosis especially if a careful medical history / examination reveals the most likely clinical cause for the lymphadenopathy, which is subsequently confirmed.