Browsing Genetics by Title

Browsing Genetics by Title

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  • H3K36 methylation reprograms gene expression to drive early gametocyte development in Plasmodium falciparum 
    Connacher, Jessica I.; Josling, Gabrielle A.; Orchard, Lindsey M.; Reader, Janette; Llinas, Manuel; Birkholtz, Lyn-Marie (BMC, 2021-04)
    BACKGROUND : The Plasmodium sexual gametocyte stages are the only transmissible form of the malaria parasite and are thus responsible for the continued transmission of the disease. Gametocytes undergo extensive functional ...
  • Habitat heterogeneity and connectivity shape microbial communities in South American peatlands 
    Oloo, Felix; Valverde, Angel; Quiroga, Maria Victoria; Vikram, Surendra; Cowan, Don A.; Mataloni, Gabriela (Nature Publishing Group, 2016-05-10)
    Bacteria play critical roles in peatland ecosystems. However, very little is known of how habitat heterogeneity affects the structure of the bacterial communities in these ecosystems. Here, we used amplicon sequencing ...
  • A haploid system of sex determination in the brown alga Ectocarpus sp. 
    Ahmed, Sophia; Cock, J. Mark; Pessia, Eugenie; Luthringer, Remy; Cormier, Alexandre; Robuchon, Marine; Sterck, Lieven; Peters, Akira F.; Dittami, Simon M.; Corre, Erwan; Valero, Myriam; Aury, Jean-Marc; Roze, Denis; Van de Peer, Yves; Bothwell, John; Marais, Gabriel A.B.; Coelho, Susana M. (Elsevier, 2014-09)
    BACKGROUND : A common feature of most genetic sex-determination systems studied so far is that sex is determined by nonrecombining genomic regions, which can be of various sizes depending on the species. These regions have ...
  • Haplotype-resolved genome assembly and allele-specific gene expression in cultivated ginger 
    Cheng, Shi-Ping; Jia, Kai-Hua; Liu, Hui; Zhang, Ren-Gang; Li, Zhi-Chao; Zhou, Shan-Shan; Shi, Tian-Le; Ma, Ai-Chu; Yu, Cong-Wen; Gao, Chan; Cao, Guang-Lei; Zhao, Wei; Nie, Shuai; Guo, Jing-Fang; Jiao, Si-Qian; Tian, Xue-Chan; Yan, Xue-Mei; Bao, Yu-Tao; Yun, Quan-Zheng; Wang, Xin-Zhu; Porth, Ilga; El-Kassaby, Yousry A.; Wang, Xiao-Ru; Li, Zhen; Van de Peer, Yves; Mao, Jian-Feng (Springer Nature, 2021-08)
    Ginger (Zingiber officinale) is one of the most valued spice plants worldwide; it is prized for its culinary and folk medicinal applications and is therefore of high economic and cultural importance. Here, we present a ...
  • Hardwood tree genomics : unlocking woody plant biology 
    Tuskan, Gerald A.; Groover, Andrew T.; Schmutz, Jeremy; DiFazio, Stephen Paul; Myburg, Alexander Andrew; Grattapaglia, Dario; Smart, Lawrence B.; Yin, Tongming; Aury, Jean-Marc; Kremer, Antoine; Leroy, Thibault; Le Provost, Gregoire; Plomion, Christophe; Carlson, John E.; Randall, Jennifer; Westbrook, Jared; Grimwood, Jane; Muchero, Wellington; Jacobson, Daniel; Michener, Joshua K. (Frontiers Media, 2018-12-17)
    Woody perennial angiosperms (i.e., hardwood trees) are polyphyletic in origin and occur in most angiosperm orders. Despite their independent origins, hardwoods have shared physiological, anatomical, and life history ...
  • Harmonising the fields of invasion science and forest pathology 
    Paap, Trudy; Wingfield, Michael J.; Burgess, Treena I.; Hulbert, J.M. (Joey); Santini, Alberto (Pensoft Publishers, 2020-10-15)
    Invasive alien species are widely recognised as significant drivers of global environmental change, with far reaching ecological and socio-economic impacts. The trend of continuous increases in first records, with no ...
  • Harnessing the potential of precision pest management in plantation forests 
    Slippers, Bernard; Hurley, Brett Phillip; Allison, Jeremy D. (NISC (Pty) Ltd and Informa UK Limited (trading as Taylor and Francis Group), 2020)
    There are numerous new and emerging technologies that allow for greater precision in forest pest management, from sequencing and chemical analyses to data collection through smart technologies, and integration, analysis ...
  • The healthy human blood microbiome : fact or fiction? 
    Castillo, Diego J.; Rifkin, Riaan F.; Cowan, Don A.; Potgieter, Marnie (Frontiers Media, 2019-05-08)
    The blood that flows perpetually through our veins and arteries performs numerous functions essential to our survival. Besides distributing oxygen, this vast circulatory system facilitates nutrient transport, deters ...
  • Hereditary paraganglioma in South Africa : An investigation of the Succinate-ubiquinone Oxidoreductase subunit genes, SDHB, SDHC and SDHD 
    Louw, Nadja (University of Pretoria, 2014)
    Paraganglioma (PGL) are tumours occurring in the head-and-neck -, intra-abdominal - and thoracic paraganglia. Germ-line mutations in genes encoding the subunits of mitochondrial succinate dehydrogenase complex II (SDHB, ...
  • hfAIM : a reliable bioinformatics approach for in silico genome-wide identification of autophagy-associated Atg8-interacting motifs in various organisms 
    Xie, Qingjun; Tzfadia, Oren; Levy, Matan; Weithorn, Efrat; Peled-Zehavi, Hadas; Van Parys, Thomas; Van de Peer, Yves; Galili, Gad (Taylor and Francis, 2016-02)
    Most of the proteins that are specifically turned over by selective autophagy are recognized by the presence of short Atg8 interacting motifs (AIMs) that facilitate their association with the autophagy apparatus. Such ...
  • Hierarchical transcriptional control regulates Plasmodium falciparum sexual differentiation 
    Van Biljon, Riette Andele; Van Wyk, Roelof Daniel Jacobus; Painter, Heather J.; Orchard, Lindsey; Reader, Janette; Niemand, Jandeli; Llinas, Manuel; Birkholtz, Lyn-Marie (BioMed Central, 2019-12)
    BACKGROUND : Malaria pathogenesis relies on sexual gametocyte forms of the malaria parasite to be transmitted between the infected human and the mosquito host but the molecular mechanisms controlling gametocytogenesis ...
  • High diversity of Diaporthe species associated with pear shoot canker in China 
    Guo, Y.S.; Crous, Pedro W.; Bai, Q.; Fu, M.; Yang, M.M.; Wang, X.H.; Du, Y.M.; Hong, N.; Xu, W.X.; Wang, G.P. (Naturalis Biodiversity Center and Centraalbureau voor Schimmelcultures, 2020-02-06)
    Species of Diaporthe (syn. Phomopsis) are important endophytes, saprobes and pathogens, infecting a wide range of plants and resulting in important crop diseases. However, the species occurring on pear remain largely unresolved. ...
  • High diversity, inbreeding and a dynamic Pleistocene demographic history revealed by African buffalo genomes 
    De Jager, Deon; Glanzmann, Brigitte; Möller, Marlo; Hoal, Eileen; Van Helden, Paul; Harper, Cindy Kim; Bloomer, Paulette (Nature Research, 2021)
    Genomes retain records of demographic changes and evolutionary forces that shape species and populations. Remnant populations of African bufalo (Syncerus cafer) in South Africa, with varied histories, provide an opportunity ...
  • High genetic diversity of Fusarium circinatum associated with the first outbreak of pitch canker on Pinus patula in South Africa 
    Fru, Felix Fon; Steenkamp, Emma Theodora; Wingfield, Michael J.; Roux, Jolanda (NISC (Pty) Ltd and Informa UK Limited (trading as Taylor & Francis Group), 2019)
    The disease known as pitch canker results from infection of Pinus species by the fungus Fusarium circinatum. This fungus also causes a serious root disease of Pinus seedlings and cuttings in forestry nurseries. Pinus radiata ...
  • High levels of genetic diversity and cryptic recombination is widespread in introduced Diplodia pinea populations 
    Bihon, Wubetu; Burgess, Treena I.; Slippers, Bernard; Wingfield, Michael J.; Wingfield, Brenda D. (Springer, 2012-01)
    Introduced populations of organisms typically have reduced diversity compared to those that are native. It is, therefore, unusual that introduced populations of the fungal tree pathogen Diplodia pinea have been shown ...
  • High levels of imported asymptomatic malaria but limited local transmission in KwaZulu‑Natal, a South African malaria‑endemic province nearing malaria elimination 
    Raman, Jaishree; Gast, Laura; Balawanth, Ryleen; Tessema, Sofonias; Brooke, Basil; Maharaj, Rajendra; Munhenga, Givemore; Tshikae, Power; Lakan, Vishan; Mwamba, Tshiama; Makowa, Hazel; Sangweni, Lindi; Mkhabela, Moses; Zondo, Nompumelelo; Mohulatsi, Ernest; Nyawo, Zuziwe; Ngxongo, Sifiso; Msimang, Sipho; Dagata, Nicole; Greenhouse, Bryan; Birkholtz, Lyn-Marie; Shirreff, George; Graffy, Rebecca; Qwabe, Bheki; Moonasar, Devanand (BioMed Central, 2020-04-15)
    BACKGROUND : KwaZulu-Natal, one of South Africa’s three malaria endemic provinces, is nearing malaria elimination, reporting fewer than 100 locally-acquired cases annually since 2010. Despite sustained implementation of ...
  • High throughput development of population genetic markers for the Sirex noctilio woodwasp and its nematode parasite, Deladenus siricidicola 
    Mlonyeni, X.O.M. (Xolile Osmond Mnyamezeli) (University of Pretoria, 2010)
    Sirex noctilio is a major pest to Pinus spp. and threat to the Forestry industry in the Southern Hemisphere. The varying level of efficacy of its primary biological control agent, Deladenus siricidicola, is also of serious ...
  • High within-host genetic variation of the nematode Spirocerca lupi in a high-density urban dog population 
    De Waal, Pamela Jean; Gous, Annemarie; Clift, Sarah Jane; Greeff, Jacobus Maree (Elsevier, 2012-06)
    The nematode worm Spirocerca lupi has a cosmopolitan distribution and can cause the death of its final canid host, typically dogs. While its life cycle, which involves a coprophagous beetle intermediate host, a number ...
  • A high-density Diversity Arrays Technology (DArT) microarray for genome-wide genotyping in Eucalyptus 
    Sansaloni, Carolina P.; Petroli, Cesar D.; Carling, Jason; Hudson, Corey J.; Steane, Dorothy A.; Myburg, Alexander Andrew; Grattapaglia, Dario; Vaillancourt, Rene E.; Kilian, Andrzej (BioMed Central, 2010)
    BACKGROUND: A number of molecular marker technologies have allowed important advances in the understanding of the genetics and evolution of Eucalyptus, a genus that includes over 700 species, some of which are used worldwide ...
  • High-density genetic linkage maps with over 2,400 sequence-anchored DArT markers for genetic dissection in an F2 pseudo-backcross of Eucalyptus grandis × E. urophylla 
    Kullan, Anand Raj Kumar; Van Dyk, Maria M.; Jones, Nicoletta B.; Kanzler, Arnulf; Bayley, Arlene; Myburg, Alexander Andrew (Springer, 2012-02)
    Traits that differentiate cross-fertile plant species can be dissected by genetic linkage analysis in interspecific hybrids. Such studies have been greatly facilitated in Eucalyptus tree species by the recent development ...