Bone remodelling in a healthy body is in constant balance, maintaining an adaptive and robust skeletal system.
In osteoporosis this balance is disrupted with the rates of osteoclastic bone resorption exceeding osteoblastic
bone ...
Bone undergoes continuous remodeling by a coupled action between osteoblasts and osteoclasts. During osteoporosis, osteoclast activity is often elevated leading to increased bone destruction. Hence, osteoclasts are deemed ...
Elevated bone loss induced by osteoclasts is a critical and most commonly observed pathological complication during osteolytic diseases such as osteoporosis. Hence, attenuation of osteoclast formation or function is a ...
