Hanyroup, Sharika; Anderson, Ross Calley; Nataraja, Selvaraj; Yu, Henry N.; Millar, Robert P.; Newton, Claire L.(Oxford University Press, 2021-12)
Mutations in G protein-coupled receptors (GPCRs) underlie numerous diseases. Many cause receptor misfolding and failure to reach the cell surface. Pharmacological chaperones are cell-permeant small molecules that engage ...
Anderson, Ross Calley; Newton, Claire L.; Millar, Robert P.(Frontiers Media, 2019-01-23)
The follicle-stimulating hormone receptor (FSHR) has been targeted therapeutically
for decades, due to its pivotal role in reproduction. To date, only purified and
recombinant/biosimilar FSH have been used to target FSHR ...
