Browsing Research Articles (Physiology) by Title

Browsing Research Articles (Physiology) by Title

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  • Joubert, Annie M.; Van Zyl, Hermia; Laurens, Johannes B.; Lottering, Mona-Liza (Centro Regional de Investigaciones Cientificas Y Tecnologicas / Universidad Nacional de Cuyo, 2009)
    C2- and C4-position 17β-estradiol metabolites play an important role in breast carcinogenesis. 2-Hydroxyestradiol and 4-hydroxyestradiol are implicated in tumorigenesis via two pathways. These pathways entail increased ...
  • Wolmarans, Elize; Boy, S.C. (Sonja); Nel, Sulette; Mercier, Anne Elisabeth; Pepper, Michael Sean (Springer, 2017-11)
    The recurrence and/or lack of response of certain tumors to radio- and chemotherapy has been attributed to a small subpopulation of cells termed cancer stem cells (CSCs). CSCs have been identified in many tumors (including ...
  • Nielsen, Vance G.; Pretorius, Etheresia (Elsevier, 2014-03)
    Within the past decade there have been several investigations attempting to define the impact of exogenous and endogenous carbon monoxide exposure on hemostasis. Critically, two bodies of literature have emerged, with carbon ...
  • Nielsen, Vance G.; Pretorius, Etheresia; Bester, Janette; Jacobsen, Wayne K.; Boyle, Patrick K.; Reinhard, Joao P. (Bentham Science, 2015-01)
    Alzheimer’s disease (AD) is a significant source of morbidity and mortality for millions of people worldwide, and multiple potential etiologies have been postulated to contribute to AD. Among these, spontaneous cerebral ...
  • Du Toit, Peet J.; Kruger, Ernst H.; Govender, Catherine; Henning, E.; Kleynhans, Michael; Wood, Paola Silvia; De Villiers, Nico P.; Van Rooyen, J.M.; Fletcher, Lizelle; Grant, C.C. (Catharina Cornelia) (Africa Association for Health, Physical Education, Recreation, Sport and Dance, 2012-03)
    Stress is an unavoidable part of everyday life due to the demands and stressors associated with modern lifestyle. Health risks provoked by this increasingly prevalent condition lead to cardiovascular disease, which ultimately ...
  • Deepak, Vishwa; Kasonga, Abe E.; Kruger, Marlena C.; Coetzee, Magdalena (Pharmaceutical Society of Japan, 2016-07)
    Bone is a dynamic tissue that undergoes continuous remodeling coupled with the action of osteoblasts and osteoclasts. Osteoclast activity is elevated during osteoporosis and periodontitis resulting in excessive loss of ...
  • Ker, James A.; Van Wyk, C.J. (Clinics Cardiv, 2007-11)
    Considerable controversy exists regarding the cardiovascular safety of COX-2 inhibitors, both in patients with and without established cardiovascular disease. Currently, the major focus is on thrombotic complications ...
  • Soma, Prashilla; Ellemdin, Shiraz (Clinics Cardiv, 2012-09)
    It is now clear that hepatopulmonary syndrome (HPS) may occur and contribute significantly to gas exchange abnormalities in the setting of other cardiopulmonary abnormalities. Since there is no gold-standard diagnostic ...
  • Viljoen, Margaretha; Panzer, Annie (In House Publications, 2007-08)
    The central noradrenergic system belongs to a group of brainstem neuromodulatory systems previously referred to as the ascending reticular activating system. In this article a heuristic model is presented of the central ...
  • Buys, A.V. (Antonia Vergina); Van Rooy, Mia-Jeanne; Soma, Prashilla; Van Papendorp, D.H. (Dirk Hermanus), 1949-; Lipinski, Boguslaw; Pretorius, Etheresia (BioMed Central, 2013-01-28)
    Red blood cells (RBCs) are highly deformable and possess a robust membrane that can withstand shear force. Previous research showed that in diabetic patients, there is a changed RBC ultrastructure, where these cells ...
  • Olumuyiwa-Akeredolu, Oore-ofe O.; Soma, Prashilla; Buys, A.V. (Antonia Vergina); Debusho, Legesse Kassa; Pretorius, Etheresia (Elsevier, 2017-12)
    The inflammatory burden of the complex rheumatoid arthritis (RA) disease affects several organ-systems, including rheological properties of blood and its formed elements. Red blood cells (RBCs) are constantly exposed to ...
  • Verwey, M.; Joubert, Annie M.; Visagie, M.H. (Michelle Helen); Annie M.; Theron, A.E. (Biomedical Research Press, 2016)
    Breast cancer is the most prevalent cancer in women worldwide, contributing to 14% of all new cancer cases and 6.8% of all cancer deaths in 2014. A new area of cancer research has arisen from the discovery of cancer ...
  • Ker, James A. (OpenJournals Publishing, 2010-01)
    No abstract available.
  • Swanepoel, A.C. (Albe Carina); Visagie, Amcois; De Lange, Zelda; Emmerson, Odette; Nielsen, Vance G.; Pretorius, Etheresia (Elsevier, 2016-10)
    BACKGROUND : The effect of endogenous hormone concentrations, specifically 17β-estradiol and progesterone, on fibrin network formation has not been established. OBJECTIVES : It is essential to understand natural hormone ...
  • Soma, Prashilla; Ellemdin, Shiraz (Medpharm Publications, 2009-05)
    Disseminated histoplasmosis can be the initial clue to the presence of AIDS. In HIV infected patients, histoplasmosis can present with unusual manifestations, without a positive exposure history or outside the typical ...
  • Mqoco, T.V. (Thandi Vuyelwa); Stander, Andre; Engelbrecht, Anna-Mart; Joubert, Annie M. (Hindawi Publishing, 2019-12-11)
    Current chemotherapeutic agents have many side effects and are toxic to normal cells, providing impetus to identify agents that can effectively eliminate tumorigenic cells without damaging healthy cells. The aim of this ...
  • Ker, James A. (South African Academy of Family Practice/Primary Care, 2013)
    On average, one in four adults has hypertension.1 This figure is higher in certain regions of the world, and in certain areas within countries. Worldwide, however, the prevalence of hypertension is on the rise. The ...
  • Ker, James A. (Medpharm Publications, 2012-03)
    On average, one in four adults has hypertension. This figure is higher in certain regions of the world, and in certain regions of countries. However, the worldwide prevalence of hypertension is on the rise. The relationship ...
  • Ker, James A. (South African Academy of Family Practice/Primary Care, 2010-10)
    On average, one in four adults has hypertension.1 This figure is higher in certain regions of the world, and in certain areas within countries. Worldwide, however, the prevalence of hypertension is on the rise. The ...
  • Visagie, Amcois; Kasonga, Abe E.; Deepak, Vishwa; Moosa, Shaakirah; Marais, Sumari; Kruger, Marlena C.; Coetzee, Magdalena (MDPI Publishing, 2015-10)
    Honeybush tea, a sweet tasting caffeine-free tea that is indigenous to South Africa, is rich in bioactive compounds that may have beneficial health effects. Bone remodeling is a physiological process that involves the ...