Browsing Research Articles (Plant Science) by Subject "Naphthoquinones"

Browsing Research Articles (Plant Science) by Subject "Naphthoquinones"

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  • The naphthoquinone diospyrin is an inhibitor of DNA gyrase with a novel mechanism of action 
    Karkare, Shantanu; Chung, Terence T. H.; Collin, Frederic; Mitchenall, Lesley A.; McKay, Adam R.; Greive, Sandra J.; Meyer, Jacobus Johannes Marion; Lall, Namrita; Maxwell, Anthony (American Society for Biochemistry and Molecular Biology, 2013-02)
    Tuberculosis and other bacterial diseases represent a significant threat to human health. The DNA topoisomerases are excellent targets for chemotherapy, and DNA gyrase in particular is a well-validated target for antibacterial ...