Browsing Research Articles (Biochemistry) by Subject "Kinase inhibitor"

Browsing Research Articles (Biochemistry) by Subject "Kinase inhibitor"

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  • Potent Plasmodium falciparum gametocytocidal compounds identified by exploring the kinase inhibitor chemical space for dual active antimalarials 
    Van der Watt, Mariette Elizabeth; Reader, Janette; Churchyard, Alisje; Nondaba, Sindisiwe; Lauterbach, Sonja B.; Niemand, Jandeli; Abayomi, Sijuade; Van Biljon, Riette Andele; Connacher, Jessica I.; Van Wyk, Roelof Daniel Jacobus; Le Manach, Claire; Paquet, Tanya; González Cabrera, Diego; Brunschwig, Christel; Theron, Anjo; Lozano-Arias, Sonia; Rodrigues, Janneth F.I.; Herreros, Esperanza; Leroy, Didier; Duffy, James; Street, Leslie J.; Chibale, Kelly; Mancama, Dalu; Coetzer, Theresa L.; Birkholtz, Lyn-Marie (Oxford University Press, 2018-05)
    OBJECTIVES : Novel chemical tools to eliminate malaria should ideally target both the asexual parasites and transmissible gametocytes. Several imidazopyridazines (IMPs) and 2-aminopyridines (2-APs) have been described as ...