Browsing Research Articles (Biochemistry) by Subject "In vivo"

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Potential phytochemicals in the fight against skin cancer : current landscape and future perspectives

Iqbal, Javed; Abbasi, Banzeer Ahsan; Ahmad, Riaz; Batool, Riffat; Mahmood, Tariq; Ali, Barkat; Khalil, Ali Talha; Kanwal, Sobia; Afzal Shah, Sayed; Alam, Muhammad Maqsood; Bashir, Sheeza; Badshah, Hussain; Munir, Akhtar (Elsevier, 2019-01)

Skin cancer is a life threatening disease and their prevalence and risk has been increasing over the past three decades causing significant loss to human health worldwide. Mostly skin cancer has developed resistance against ...
Structure-activity relationship studies and Plasmodium life cycle profiling identifies pan-active N-aryl-3-trifluoromethyl pyrido[1,2-a]benzimidazoles which are efficacious in an in vivo mouse model of malaria

Mayoka, Godfrey; Njoroge, Mathew; Okombo, John; Gibhard, Liezl; Sanches-Vaz, Margarida; Fontinha, Diana; Birkholtz, Lyn-Marie; Reader, Janette; Van der Watt, Mariette Elizabeth; Coetzer, Theresa L.; Lauterbach, Sonja B.; Churchyard, Alisje; Bezuidenhout, Belinda C.; Egan, Timothy J.; Yeates, Clive Leonard; Wittlin, Sergio; Prudêncio, Miguel; Chibale, Kelly (American Chemical Society, 2019)

Structure–activity relationship studies involving N-aryl-3-trifluoromethyl pyrido[1,2-a]benzimidazoles (PBI) identified several compounds possessing potent in vitro activities against the asexual blood, liver, and gametocyte ...

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