Browsing Research Articles (Biochemistry) by UP Author "Barnard, Bernice"

Browsing Research Articles (Biochemistry) by UP Author "Barnard, Bernice"

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  • Inhibition of p-aminobenzoate and folate syntheses in plants and apicomplexan parasites by the natural product rubreserine 
    Camara, Djeneb; Bisanz, Cordelia; Barette, Caroline; Van Daele, Jeroen; Human, Esmare; Barnard, Bernice; Van der Straeten, Dominique; Stove, Christophe P.; Lambert, Willy E.; Douce, Roland; Marechal, Eric; Birkholtz, Lyn-Marie; Cesbron-Delauw, Marie-France; Dumas, Renaud; Rebeille, Fabrice (American Society for Biochemistry and Molecular Biology, 2012-05)
    BACKGROUND: pABA biosynthesis is a potential target for antifolate drugs. RESULTS: Rubreserine inhibits GAT-ADCS, an enzyme involved in pABA biosynthesis, and decreased the folate content in Arabidopsis and Toxoplasma. ...