Browsing Research Articles (Biochemistry) by Title

Browsing Research Articles (Biochemistry) by Title

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  • Moyo, Phanankosi; Kunyane, Phaladi; Selepe, Mamoalosi A.; Eloff, Jacobus Nicolaas; Niemand, Jandeli; Louw, Abraham Izak; Maharaj, Vinesh J.; Birkholtz, Lyn-Marie (BioMed Central, 2019-03-08)
    BACKGROUND : Optimal adoption of the malaria transmission-blocking strategy is currently limited by lack of safe and efficacious drugs. This has sparked the exploration of different sources of drugs in search of ...
  • Williams, Marni; Sprenger, Janina; Human, Esmare; Al-Karadaghic, Salem; Persson, Lo; Louw, Abraham Izak; Birkholtz, Lyn-Marie (Elsevier B.V., 2011)
    Plasmodium falciparum like other organisms is dependent on polyamines for proliferation. Polyamine biosynthesis in these parasites is regulated by a unique bifunctional S-adenosylmethionine decarboxylase/ornithine decarboxylase ...
  • Martinez-Martinez, Monica; Alcaide, María; Tchigvintsev, Anatoli; Reva, Oleg N.; Polaina, Julio; Bargiela, Rafael; Guazzaroni, María-Eugenia; Chicote, Álvaro; Canet, Albert; Valero, Francisco; Eguizabal, Eugenio Rico; Guerrero, María del Carmen; Yakunin, Alexander F.; Ferrer, Manuel (American Society for Microbiology, 2013-06)
    The esterases and lipases from the / hydrolase superfamily exhibit an enormous sequence diversity, fold plasticity, and activities. Here, we present the comprehensive sequence and biochemical analyses of seven distinct ...
  • Van der Nest, Ariska; Wingfield, Michael J.; Ortiz, Paulo C.; Barnes, Irene (International Mycological Association, 2019-06-07)
    Lecanosticta acicola causes the disease known as brown spot needle blight (BSNB), on Pinus species. The pathogen is thought to have a Central American centre of origin. This was based on the morphological variation between ...
  • Anderson, Aaron; Kotze, Johann; Shwiff, Stephanie A; Hatch, Brody; Slootmaker, Chris; Conan, Anne; Knobel, Darryn Leslie; Nel, Louis Hendrik (Public Library of Science, 2019-05-22)
    We present a new modeling tool that can be used to maximize the impact of canine rabies management resources that are available at the local level. The model is accessible through a web-based interface that allows for ...
  • Lee, Charles K.; Laughlin, Daniel C.; Bottos, Eric M.; Caruso, Tancredi; Joy, Kurt; Barrett, John E.; Brabyn, Lars; Nielsen, Uffe N.; Adams, Byron J.; Wall, Diana H.; Hopkins, David W.; Pointing, Stephen B.; McDonald, Ian R.; Cowan, Don A.; Banks, Jonathan C.; Stichbury, Glen A.; Jones, Irfon; Zawar-Reza, Peyman; Katurji, Marwan; Hogg, Ian D.; Sparrow, Ashley D.; Storey, Bryan C.; Green, T. G. Allan; Cary, S. Craig (Nature Research, 2019-02-15)
    Abiotic and biotic factors control ecosystem biodiversity, but their relative contributions remain unclear. The ultraoligotrophic ecosystem of the Antarctic Dry Valleys, a simple yet highly heterogeneous ecosystem, is a ...
  • Nel, Wilma Janine; Duong, Tuan A.; De Beer, Z. Wilhelm; Wingfield, Michael J. (Wiley, 2019-06)
    Black root rot caused by the pathogen Thielaviopsis basicola has been known since the mid 1800s. The disease is important on many agricultural and ornamental plant species and has been found in at least 31 countries. Since ...
  • Saasa, Valentine; Beukes, Mervyn; Lemmer, Yolandy; Mwakikunga, Bonex (MDPI, 2019-12-17)
    Analysis of volatile organic compounds in the breath for disease detection and monitoring has gained momentum and clinical significance due to its rapid test results and non-invasiveness, especially for diabetes mellitus ...
  • Jami, Fahimeh; Marincowitz, Seonju; Slippers, Bernard; Crous, Pedro W.; Le Roux, Johannes J.; Richardson, David M.; Wingfield, Michael J. (Elsevier, 2019-11)
    Acacia koa and A. heterophylla are commonly occurring native trees on the Hawaiian Islands and La Réunion, respectively. A recent phylogenetic study suggested that A. heterophylla renders A. koa paraphyletic, and that the ...
  • Le Roux, Karlien; Prinsloo, Linda Charlotta; Meyer, Debra (Elsevier, 2015-03)
    Fourier Transform Infrared (FTIR) spectroscopy is finding increasing biological application, for example in the analysis of diseased tissues and cells, cell cycle studies and investigating the mechanisms of action ...
  • Simpson, M.C. (Melissa Claire); Coetzee, Martin Petrus Albertus; Van der Nest, Magrieta Aletta; Wingfield, Michael J.; Wingfield, Brenda D. (Elsevier, 2018-12)
    Mating is central to many fungal life cycles and is controlled by genes at the mating-type (MAT) locus. These genes determine whether the fungus will be self-sterile (heterothallic) or self-fertile (homothallic). Species ...
  • Strauss, Steven H.; Boerjan, Wout; Chiang, Vincent; Costanza, Adam; Coleman, Heather; Davis, John M.; Lu, Meng-Zhu; Mansfield, Shawn D.; Merkle, Scott; Myburg, Alexander Andrew; Nilsson, Ove; Pilate, Gilles; Powell, William; Seguin, Armand; Valenzuela, Sofia (American Association for the Advancement of Science, 2019-08-23)
    Forest certification bodies were established to provide consumers with confidence that they are purchasing sustainably sourced wood products.
  • Hergert, Melinda; Le Roux, Kevin; Nel, Louis Hendrik (BioMed Central, 2018-09-10)
    BACKGROUND : Canine rabies has been enzootic in the dog population of the KwaZulu-Natal province of South Africa since the mid-1970s and has been associated with high rates of human exposures and frequent transmissions ...
  • Mosina, Ntsoaki Leticia; Schubert, Wolf-Dieter; Cowan, Don A. (Springer, 2019-11)
    Glycoside hydrolases, particularly cellulases, xylanases and mannanases, are essential for the depolymerisation of lignocellulosic substrates in various industrial bio-processes. In the present study, a novel glycoside ...
  • Sippel, Katherine H.; Stander, Andre; Tu, Chingkuang; Venkatakrishnan, Balasubramanian; Robbins, Arthur H.; Agbandje-McKenna, Mavis; Joubert, Fourie; Joubert, Annie M.; McKenna, Robert (Bentham Science, 2011-10)
    Sulfamated 2-ethylestra compounds have demonstrated strong anticancer activity, high bioavailability and an ability to bypass liver metabolism by reversibly binding carbonic anhydrase (CA) II in erythrocytes. Another CA ...
  • Adejoro, Festus Adeyemi; Hassen, Abubeker; Thantsha, Mapitsi Silvester (Asian-Australasian Association of Animal Production Societies, 2019)
    OBJECTIVE : The use of tannin extract and other phytochemicals as dietary additives in ruminants is becoming more popular due to their wide biological actions such as in methane mitigation, bypass of dietary protein, ...
  • Xia, Zhi-Gui; Wang, Ru-Bo; Wang, Duo-Quan; Feng, Jun; Zheng, Qi; Deng, Chang-Sheng; Abdulla, Salim; Guan, Ya-Yi; Ding, Wei; Yao, Jia-Wen; Qian, Ying-Jun; Bosman, Andrea; Newman, Robert David; Ernest, Tambo; O’leary, Michael; Xiao, Ning (Elsevier, 2014)
    Malaria has affected human health globally with a significant burden of disease, and also has impeded social and economic development in the areas where it is present. In Africa, many countries have faced serious challenges ...
  • McTaggart, Alistair R.; Duong, Tuan A.; Le, Vang Quy; Shuey, Louise S.; Smidt, Werner; Naidoo, Sanushka; Wingfield, Michael J.; Wingfield, Brenda D. (Future Medicine, 2018-11)
    It is challenging to sequence and assemble genomes of obligate plant pathogens and microorganisms because of limited amounts of DNA, comparatively large genomes and high numbers of repeat regions. We sequenced the 1.2 ...
  • Naidoo, Yashini; Valverde, Angel; Cason, Errol D.; Pierneef, Rian E.; Cowan, Don A. (Elsevier, 2020-06)
    The exhaustive use of antibiotics in humans, animal farming and other agricultural practices has resulted in the frequent appearance of antibiotic resistant bacteria in human-impacted habitats. However, antibiotic resistance ...
  • Mortlock, Marinda; Dietrich, Muriel; Weyer, Jacqueline; Paweska, Janusz Tadeusz; Markotter, Wanda (MDPI, 2019-01)
    The Egyptian rousette bat (Rousettus aegyptiacus) has previously been implicated as the natural host of a zoonotic rubulavirus; however, its association with rubulaviruses has been studied to a limited extent. Urine, ...