Browsing Research Articles (Medical Virology) by UP Author "Swanepoel, Robert"

Browsing Research Articles (Medical Virology) by UP Author "Swanepoel, Robert"

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  • Clinical features and patient management of Lujo hemorrhagic fever 
    Sewlall, Nivesh H.; Richards, Guy A.; Duse, Adriano; Swanepoel, Robert; Paweska, Janusz Tadeusz; Blumberg, Lucille Hellen; Dinh, Thu-Ha; Bausch, Daniel (Public Library of Science, 2014-11-13)
    BACKGROUND : In 2008 a nosocomial outbreak of five cases of viral hemorrhagic fever due to a novel arenavirus, Lujo virus, occurred in Johannesburg, South Africa. Lujo virus is only the second pathogenic arenavirus, after ...
  • Comparative analysis of the L, M, and S RNA segments of Crimean-Congo haemorrhagic fever virus isolates from southern Africa 
    Goedhals, Dominique; Bester, P.A.; Paweska, Janusz Tadeusz; Swanepoel, Robert; Burt, F.J. (Wiley, 2015-05)
    Crimean–Congo haemorrhagic fever virus (CCHFV) is a member of the Bunyaviridae family with a tripartite, negative sense RNA genome. This study used predictive software to analyse the L (large), M (medium), and S (small) ...
  • Detection of Rift Valley fever virus in Aedes (Aedimorphus) durbanensis, South Africa 
    Van den Bergh, Carien; Thompson, P.N. (Peter N.); Swanepoel, Robert; Almeida, Antonio Paulo Gouveia; Paweska, Janusz Tadeusz; Van Vuren, Petrus Jansen; Wilson, William C.; Kemp, Alan; Venter, Estelle Hildegard (MDPI, 2022-01-21)
    Rift Valley fever virus (RVFV) is a mosquito-borne, zoonotic phlebovirus-causing disease in domestic ruminants and humans in Africa, the Arabian Peninsula and some Indian Ocean islands. Outbreaks, characterized by abortion ...
  • Filovirus RefSeq entries : evaluation and selection of Filovirus type variants, type sequences, and names 
    Kuhn, Jens H.; Andersen, Kristian G.; Bao, Yiming M.; Bavari, Sina; Becker, Stephan; Bennett, Richard S.; Bergman, Nicholas H.; Blinkova, Olga; Bradfute, Steven; Brister, J. Rodney; Bukreyev, Alexander A.; Chandran, Kartik; Chepurnov, Alexander A.; Davey, Robert A.; Dietzgen, Ralf G.; Doggett, Norman A.; Dolnik, Olga; Dye, John M.; Enterlein, Sven; Fenimore, Paul W.; Formenty, Pierre; Freiberg, Alexander N.; Garry, Robert F.; Garza, Nicole L.; Gire, Stephen K.; Gonzalez, Jean-Paul; Griffiths, Anthony; Happi, Christian T.; Hensley, Lisa E.; Herbert, Andrew S.; Hevey, Michael C.; Hoenen, Thomas; Honko, Anna N.; Ignatyev, Georgy M.; Jahrling, Peter B.; Johnson, Joshua C.; Johnson, Karl M.; Kindrachuk, Jason; Klenk, Hans-Dieter; Kobinger, Gary; Kochel, Tadeusz J.; Lackemeyer, Matthew G.; Lackner, Daniel F.; Leroy, Eric M.; Lever, Mark S.; Muhlberger, Elke; Netesov, Sergey V.; Olinger, Gene G.; Omilabu, Sunday A.; Palacios, Gustavo; Panchal, Rekha G.; Park, Daniel J.; Patterson, Jean L.; Paweska, Janusz Tadeusz; Peters, Clarence J.; Pettitt, James; Pitt, Louise; Radoshitzky, Sheli R.; Ryabchikova, Elena I.; Saphire, Erica Ollmann; Sabeti, Pardis C.; Sealfon, Rachel; Shestopalov, Aleksandr M.; Smither, Sophie J.; Sullivan, Nancy J.; Swanepoel, Robert; Takada, Ayato; Towner, Jonathan S.; Van der Groen, Guido; Volchkov, Viktor E.; Volchkova, Valentina A.; Wahl-Jensen, Victoria; Warren, Travis K.; Warfield, Kelly L.; Weidmann, Manfred; Nichol, Stuart T. (MDPI Publishing, 2014)
    Sequence determination of complete or coding-complete genomes of viruses is becoming common practice for supporting the work of epidemiologists, ecologists, virologists, and taxonomists. Sequencing duration and costs are ...
  • Genetic determinants of virulence in pathogenic lineage 2 West Nile virus strains 
    Botha, Elizabeth Magdelena; Markotter, Wanda; Wolfaardt, Marianne; Paweska, Janusz Tadeusz; Swanepoel, Robert; Palacios, Gustavo; Nel, Louis Hendrik; Venter, Marietjie (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2008-02)
    We determined complete genome sequences of lineage 2 West Nile virus (WNV) strains isolated from patients in South Africa who had mild or severe WNV infections. These strains had previously been shown to produce either ...
  • Genome sequence analysis of in vitro and in vivo phenotypes of Bunyamwera and Ngari virus isolates from Northern Kenya 
    Odhiambo, Collins; Venter, Marietjie; Limbaso, Konongoi; Swanepoel, Robert; Sang, Rosemary; Aguilar, Patricia V. (Public Library of Science, 2014-08-25)
    Biological phenotypes of tri-segmented arboviruses display characteristics that map to mutation/s in the S, M or L segments of the genome. Plaque variants have been characterized for other viruses displaying varied ...
  • Lineage 2 West Nile virus as cause of fatal neurologic disease in horses, South Africa 
    Venter, Marietjie; Human, Stacey; Zaayman, Dewald; Gerdes, Gertruida Hermanna; Williams, June Heather; Steyl, Johan Christian Abraham; Leman, Patricia A.; Paweska, Janusz Tadeusz; Setzkorn, Hildegard; Rous, Gavin; Murray, Sue; Parker, Rissa; Donnellan, Cynthia Mary Bridget; Swanepoel, Robert (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2009-05-06)
    Serologic evidence suggests that West Nile virus (WNV) is widely distributed in horses in Southern Africa. However, because few neurologic cases have been reported, endemic lineage 2 strains were postulated to be non-pathogenic ...
  • Masstag polymerase chain reaction for differential diagnosis of viral hemorrhagic fevers 
    Palacios, Gustavo; Briese, Thomas; Kapoor, Vishal; Jabado, Omar; Liu, Zhiqiang; Venter, Marietjie; Zhai, Junhui; Renwick, Neil; Grolla, Allen; Geisbert, Thomas W.; Drosten, Christian; Towner, Jonathan S.; Ju, Jingyue; Paweska, Janusz Tadeusz; Nichol, Stuart T.; Swanepoel, Robert; Feldmann, Heinz; Jahrling, Peter B.; Lipkin, Ian W. (Centers for Disease Control and Prevention, 2006-04)
    Viral hemorrhagic fevers are associated with high rates of illness and death. Although therapeutic options are limited, early differential diagnosis has implications for containment and may aid in clinical management. We ...
  • Mosquito-borne arboviruses of African origin : review of key viruses and vectors 
    Braack, L.E.O.; De Almeida, Antonio Paulo Gouveia; Cornel, Anthony J.; Swanepoel, Robert; De Jager, Christiaan (BioMed Central, 2018-01-09)
    Key aspects of 36 mosquito-borne arboviruses indigenous to Africa are summarized, including lesser or poorly-known viruses which, like Zika, may have the potential to escape current sylvatic cycling to achieve greater ...
  • Next-generation sequencing of southern African Crimean-Congo haemorrhagic fever virus isolates reveals a high frequency of M segment reassortment 
    Goedhals, Dominique; Bester, P.A.; Paweska, Janusz Tadeusz; Swanepoel, Robert; Burt, F.T. (Cambridge University Press, 2014-05-01)
    Crimean Congo haemorrhagic fever virus (CCHFV) is a bunyavirus with a single-stranded RNA genome consisting of three segments (S, M, L), coding for the nucleocapsid protein, envelope glycoproteins and RNA polymerase, ...
  • Nomenclature- and database-compatible names for the two Ebola virus variants that emerged in Guinea and the Democratic Republic of the Congo in 2014 
    Kuhn, Jens H.; Andersen, Kristian G.; Baize, Sylvain; Bào, Yīmíng; Bavari, Sina; Berthet, Nicolas; Blinkova, Olga; Brister, J. Rodney; Clawson, Anna N.; Fair, Joseph; Gabriel, Martin; Garry, Robert F.; Gire, Stephen K.; Goba, Augustine; Gonzalez, Jean-Paul; Günther, Stephan; Happi, Christian T.; Jahrling, Peter B.; Kapetshi, Jimmy; Kobinger, Gary; Kugelman, Jeffrey R.; Leroy, Eric M.; Maganga, Gael Darren; Mbala, Placide K.; Moses, Lina M.; Muyembe-Tamfum, Jean-Jacques; N’Faly, Magassouba; Nichol, Stuart T.; Omilabu, Sunday A.; Palacios, Gustavo; Park, Daniel J.; Paweska, Janusz Tadeusz; Radoshitzky, Sheli R.; Rossi, Cynthia A.; Sabeti, Pardis C.; Schieffelin, John S.; Schoepp, Randal J.; Sealfon, Rachel; Swanepoel, Robert; Towner, Jonathan S.; Wada, Jiro; Wauquier, Nadia; Yozwiak, Nathan L.; Formenty, Pierre (MDPI Publishing, 2014-11)
    In 2014, Ebola virus (EBOV) was identified as the etiological agent of a large and still expanding outbreak of Ebola virus disease (EVD) in West Africa and a much more confined EVD outbreak in Middle Africa. Epidemiological ...
  • Phylogenetic analysis of Bunyamwera and Ngari viruses (family Bunyaviridae, genus Orthobunyavirus) isolated in Kenya 
    Odhiambo, Collins; Venter, Marietjie; Lwande, O.; Swanepoel, Robert; Sang, R. (Cambridge University Press, 2016-01)
    Orthobunyaviruses, tri-segmented, negative-sense RNA viruses, have long been associated with mild to severe human disease in Africa, but not haemorrhagic fever. However, during a Rift Valley fever outbreak in East Africa ...
  • Rapid molecular strategy for filovirus detection and characterization 
    Zhai, Junhui; Palacios, Gustavo; Towner, Jonathan S.; Jabado, Omar; Kapoor, Vishal; Venter, Marietjie; Grolla, Allen; Briese, Thomas; Paweska, Janusz Tadeusz; Swanepoel, Robert; Feldmann, Heinz; Nichol, Stuart T.; Lipkin, Ian W. (American Society for Microbiology, 2007-01)
    Filoviruses have the capacity to cause lethal outbreaks of hemorrhagic fever in primates. Here we present a simple consensus reverse transcription-PCR method for filovirus recognition and characterization and demonstrate ...
  • Rift Valley fever in Kruger National Park : do buffalo play a role in the inter-epidemic circulation of virus? 
    Beechler, B.R.; Bengis, Roy G.; Swanepoel, Robert; Paweska, Janusz Tadeusz; Kemp, Alan; Jansen van Vuren, Petrus; Joubert, J.; Ezenwa, V.O.; Jolles, Anna E. (2015-02)
    Rift Valley fever (RVF) is a zoonotic mosquito-borne virus disease of livestock and wild ruminants that has been identified as a risk for international spread. Typically, the disease occurs in geographically limited ...
  • Seasonal pulses of Marburg virus circulation in juvenile Rousettus aegyptiacus bats coincide with periods of increased risk of human infection 
    Amman, Brian R.; Carroll, Serena A.; Reed, Zachary D.; Sealy, Tara K.; Balinandi, Stephen; Swanepoel, Robert; Kemp, Alan; Erickson, Bobbie Rae; Comer, James A.; Campbell, Shelley; Cannon, Deborah L.; Khristova, Marina L.; Atimnedi, Patrick; Paddock, Christopher D.; Crockett, Rebekah J. Kent; Flietstra, Timothy D.; Warfield, Kelly L.; Unfer, Robert; Katongole-Mbidde, Edward; Downing, Robert; Tappero, Jordan W.; Zaki, Sherif R.; Rollin, Pierre E.; Ksiazek, Thomas G.; Nichol, Stuart T.; Towner, Jonathan S. (Public Library of Science, 2012-10-04)
    Marburg virus (family Filoviridae) causes sporadic outbreaks of severe hemorrhagic disease in sub-Saharan Africa. Bats have been implicated as likely natural reservoir hosts based most recently on an investigation of cases ...
  • Sindbis and Middelburg old world alphaviruses associated with disease in horses, South Africa 
    Van Niekerk, Stephanie; Human, Stacey; Williams, June Heather; Van Wilpe, Erna; Pretorius, Marthi Andréa; Swanepoel, Robert; Venter, Marietjie (Centers for Disease Control & Prevention, 2015-12)
    Old World alphaviruses were identified in 52 of 623 horses with febrile or neurologic disease in South Africa. Five of 8 Sindbis virus infections were mild; 2 of 3 fatal cases involved co-infections. Of 44 Middelburg ...
  • Transmission of West Nile virus during horse autopsy 
    Venter, Marietjie; Steyl, Johan Christian Abraham; Weyer, Jacqueline; Zaayman, Dewald; Paweska, Janusz Tadeusz; Swanepoel, Robert; Human, Stacey; Blumberg, Lucille Hellen; Leman, Patricia A. (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2010-03)
    No abstract available.
  • Virus nomenclature below the species level : a standardized nomenclature for filovirus strains and variants rescued from cDNA 
    Kuhn, Jens H.; Bao, Yımıng M.; Bavari, Sina; Becker, Stephan; Bradfute, Steven; Brauburger, Kristina; Brister, J. Rodney; Bukreyev, Alexander A.; Cai, Yıngyun; Chandran, Kartik; Davey, Robert A.; Dolnik, Olga; Dye, John M.; Enterlein, Sven; Gonzalez, Jean-Paul; Formenty, Pierre; Freiberg, Alexander N.; Hensley, Lisa E.; Hoenen, Thomas; Honko, Anna N.; Ignatyev, Georgy M.; Jahrling, Peter B.; Johnson, Karl M.; Klenk, Hans-Dieter; Kobinger, Gary; Lackemeyer, Matthew G.; Leroy, Eric M.; Lever, Mark S.; Muhlberger, Elke; Netesov, Sergewy V.; Olinger, Gene G.; Palacios, Gustavo; Patterson, Jean L.; Paweska, Janusz Tadeusz; Pitt, Louisa; Radoshitzky, Sheli R.; Ryabchikova, Elena I.; Saphire, Erica Ollmann; Shestopalov, Aleksandr M.; Smither, Sophie J.; Sullivan, Nancy J.; Swanepoel, Robert; Takada, Ayato; Towner, Jonathan S.; Van der Groen, Guido; Volchkov, Viktor E.; Volchkova, Valentina A.; Wahl-Jensen, Victoria; Warren, Travis K.; Warfield, Kelly L.; Weidmann, Manfre; Nichol, Stuart T. (Springer, 2014-05)
    Specific alterations (mutations, deletions, insertions) of virus genomes are crucial for the functional characterization of their regulatory elements and their expression products, as well as a prerequisite for the ...
  • West nile virus lineage 2 as a cause of zoonotic neurological disease in humans and horses in Southern Africa 
    Venter, Marietjie; Swanepoel, Robert (Mary Ann Liebert, 2010)
    West Nile virus (WNV) is widely distributed in South Africa, but since a few cases of neurological disease have been reported from this region, endemic lineage 2 strains were postulated to be of low virulence. Several ...