Browsing Research Articles (Medical Virology) by UP Author "Swanepoel, Robert"

Browsing Research Articles (Medical Virology) by UP Author "Swanepoel, Robert"

Sort by: Order: Results:

  • Sewlall, Nivesh H.; Richards, Guy A.; Duse, Adriano; Swanepoel, Robert; Paweska, Janusz Tadeusz; Blumberg, Lucille H.; Dinh, Thu-Ha; Bausch, Daniel (Public Library of Science, 2014-11-13)
    BACKGROUND : In 2008 a nosocomial outbreak of five cases of viral hemorrhagic fever due to a novel arenavirus, Lujo virus, occurred in Johannesburg, South Africa. Lujo virus is only the second pathogenic arenavirus, after ...
  • Goedhals, Dominique; Bester, P.A.; Paweska, Janusz Tadeusz; Swanepoel, Robert; Burt, F.J. (Wiley, 2015-05)
    Crimean–Congo haemorrhagic fever virus (CCHFV) is a member of the Bunyaviridae family with a tripartite, negative sense RNA genome. This study used predictive software to analyse the L (large), M (medium), and S (small) ...
  • Kuhn, Jens H.; Andersen, Kristian G.; Bao, Yiming M.; Bavari, Sina; Becker, Stephan; Bennett, Richard S.; Bergman, Nicholas H.; Blinkova, Olga; Bradfute, Steven; Brister, J. Rodney; Bukreyev, Alexander A.; Chandran, Kartik; Chepurnov, Alexander A.; Davey, Robert A.; Dietzgen, Ralf G.; Doggett, Norman A.; Dolnik, Olga; Dye, John M.; Enterlein, Sven; Fenimore, Paul W.; Formenty, Pierre; Freiberg, Alexander N.; Garry, Robert F.; Garza, Nicole L.; Gire, Stephen K.; Gonzalez, Jean-Paul; Griffiths, Anthony; Happi, Christian T.; Hensley, Lisa E.; Herbert, Andrew S.; Hevey, Michael C.; Hoenen, Thomas; Honko, Anna N.; Ignatyev, Georgy M.; Jahrling, Peter B.; Johnson, Joshua C.; Johnson, Karl M.; Kindrachuk, Jason; Klenk, Hans-Dieter; Kobinger, Gary; Kochel, Tadeusz J.; Lackemeyer, Matthew G.; Lackner, Daniel F.; Leroy, Eric M.; Lever, Mark S.; Muhlberger, Elke; Netesov, Sergey V.; Olinger, Gene G.; Omilabu, Sunday A.; Palacios, Gustavo; Panchal, Rekha G.; Park, Daniel J.; Patterson, Jean L.; Paweska, Janusz Tadeusz; Peters, Clarence J.; Pettitt, James; Pitt, Louise; Radoshitzky, Sheli R.; Ryabchikova, Elena I.; Saphire, Erica Ollmann; Sabeti, Pardis C.; Sealfon, Rachel; Shestopalov, Aleksandr M.; Smither, Sophie J.; Sullivan, Nancy J.; Swanepoel, Robert; Takada, Ayato; Towner, Jonathan S.; Van der Groen, Guido; Volchkov, Viktor E.; Volchkova, Valentina A.; Wahl-Jensen, Victoria; Warren, Travis K.; Warfield, Kelly L.; Weidmann, Manfred; Nichol, Stuart T. (MDPI Publishing, 2014)
    Sequence determination of complete or coding-complete genomes of viruses is becoming common practice for supporting the work of epidemiologists, ecologists, virologists, and taxonomists. Sequencing duration and costs are ...
  • Botha, Elizabeth Magdelena; Markotter, Wanda; Wolfaardt, Marianne; Paweska, Janusz Tadeusz; Swanepoel, Robert; Palacios, Gustavo; Nel, Louis Hendrik; Venter, Marietjie (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2008-02)
    We determined complete genome sequences of lineage 2 West Nile virus (WNV) strains isolated from patients in South Africa who had mild or severe WNV infections. These strains had previously been shown to produce either ...
  • Odhiambo, Collins; Venter, Marietjie; Limbaso, Konongoi; Swanepoel, Robert; Sang, Rosemary; Aguilar, Patricia V. (Public Library of Science, 2014-08-25)
    Biological phenotypes of tri-segmented arboviruses display characteristics that map to mutation/s in the S, M or L segments of the genome. Plaque variants have been characterized for other viruses displaying varied ...
  • Venter, Marietjie; Human, Stacey; Zaayman, Dewald; Gerdes, Gertruida Hermanna; Williams, J.H. (June Heather); Steyl, Johan Christian Abraham; Leman, Patricia A.; Paweska, Janusz Tadeusz; Setzkorn, Hildegard; Rous, Gavin; Murray, Sue; Parker, Rissa; Donnellan, C.M.B. (Cynthia Mary Bridget); Swanepoel, Robert (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2009-05-06)
    Serologic evidence suggests that West Nile virus (WNV) is widely distributed in horses in Southern Africa. However, because few neurologic cases have been reported, endemic lineage 2 strains were postulated to be non-pathogenic ...
  • Palacios, Gustavo; Briese, Thomas; Kapoor, Vishal; Jabado, Omar; Liu, Zhiqiang; Venter, Marietjie; Zhai, Junhui; Renwick, Neil; Grolla, Allen; Geisbert, Thomas W.; Drosten, Christian; Towner, Jonathan S.; Ju, Jingyue; Paweska, Janusz Tadeusz; Nichol, Stuart T.; Swanepoel, Robert; Feldmann, Heinz; Jahrling, Peter B.; Lipkin, Ian W. (Centers for Disease Control and Prevention, 2006-04)
    Viral hemorrhagic fevers are associated with high rates of illness and death. Although therapeutic options are limited, early differential diagnosis has implications for containment and may aid in clinical management. We ...
  • Braack, L.E.O.; De Almeida, Antonio Paulo Gouveia; Cornel, Anthony J.; Swanepoel, Robert; De Jager, Christiaan (BioMed Central, 2018-01-09)
    Key aspects of 36 mosquito-borne arboviruses indigenous to Africa are summarized, including lesser or poorly-known viruses which, like Zika, may have the potential to escape current sylvatic cycling to achieve greater ...
  • Goedhals, Dominique; Bester, P.A.; Paweska, Janusz Tadeusz; Swanepoel, Robert; Burt, F.T. (Cambridge University Press, 2014-05-01)
    Crimean Congo haemorrhagic fever virus (CCHFV) is a bunyavirus with a single-stranded RNA genome consisting of three segments (S, M, L), coding for the nucleocapsid protein, envelope glycoproteins and RNA polymerase, ...
  • Kuhn, Jens H.; Andersen, Kristian G.; Baize, Sylvain; Bào, Yīmíng; Bavari, Sina; Berthet, Nicolas; Blinkova, Olga; Brister, J. Rodney; Clawson, Anna N.; Fair, Joseph; Gabriel, Martin; Garry, Robert F.; Gire, Stephen K.; Goba, Augustine; Gonzalez, Jean-Paul; Günther, Stephan; Happi, Christian T.; Jahrling, Peter B.; Kapetshi, Jimmy; Kobinger, Gary; Kugelman, Jeffrey R.; Leroy, Eric M.; Maganga, Gael Darren; Mbala, Placide K.; Moses, Lina M.; Muyembe-Tamfum, Jean-Jacques; N’Faly, Magassouba; Nichol, Stuart T.; Omilabu, Sunday A.; Palacios, Gustavo; Park, Daniel J.; Paweska, Janusz Tadeusz; Radoshitzky, Sheli R.; Rossi, Cynthia A.; Sabeti, Pardis C.; Schieffelin, John S.; Schoepp, Randal J.; Sealfon, Rachel; Swanepoel, Robert; Towner, Jonathan S.; Wada, Jiro; Wauquier, Nadia; Yozwiak, Nathan L.; Formenty, Pierre (MDPI Publishing, 2014-11)
    In 2014, Ebola virus (EBOV) was identified as the etiological agent of a large and still expanding outbreak of Ebola virus disease (EVD) in West Africa and a much more confined EVD outbreak in Middle Africa. Epidemiological ...
  • Odhiambo, Collins; Venter, Marietjie; Lwande, O.; Swanepoel, Robert; Sang, R. (Cambridge University Press, 2016-01)
    Orthobunyaviruses, tri-segmented, negative-sense RNA viruses, have long been associated with mild to severe human disease in Africa, but not haemorrhagic fever. However, during a Rift Valley fever outbreak in East Africa ...
  • Zhai, Junhui; Palacios, Gustavo; Towner, Jonathan S.; Jabado, Omar; Kapoor, Vishal; Venter, Marietjie; Grolla, Allen; Briese, Thomas; Paweska, Janusz Tadeusz; Swanepoel, Robert; Feldmann, Heinz; Nichol, Stuart T.; Lipkin, Ian W. (American Society for Microbiology, 2007-01)
    Filoviruses have the capacity to cause lethal outbreaks of hemorrhagic fever in primates. Here we present a simple consensus reverse transcription-PCR method for filovirus recognition and characterization and demonstrate ...
  • Beechler, B.R.; Bengis, Roy G.; Swanepoel, Robert; Paweska, Janusz Tadeusz; Kemp, Alan; Jansen van Vuren, Petrus; Joubert, J.; Ezenwa, V.O.; Jolles, Anna E. (2015-02)
    Rift Valley fever (RVF) is a zoonotic mosquito-borne virus disease of livestock and wild ruminants that has been identified as a risk for international spread. Typically, the disease occurs in geographically limited ...
  • Amman, Brian R.; Carroll, Serena A.; Reed, Zachary D.; Sealy, Tara K.; Balinandi, Stephen; Swanepoel, Robert; Kemp, Alan; Erickson, Bobbie Rae; Comer, James A.; Campbell, Shelley; Cannon, Deborah L.; Khristova, Marina L.; Atimnedi, Patrick; Paddock, Christopher D.; Crockett, Rebekah J. Kent; Flietstra, Timothy D.; Warfield, Kelly L.; Unfer, Robert; Katongole-Mbidde, Edward; Downing, Robert; Tappero, Jordan W.; Zaki, Sherif R.; Rollin, Pierre E.; Ksiazek, Thomas G.; Nichol, Stuart T.; Towner, Jonathan S. (Public Library of Science, 2012-10-04)
    Marburg virus (family Filoviridae) causes sporadic outbreaks of severe hemorrhagic disease in sub-Saharan Africa. Bats have been implicated as likely natural reservoir hosts based most recently on an investigation of cases ...
  • Van Niekerk, Stephanie; Human, Stacey; Williams, J.H. (June Heather); Van Wilpe, Erna; Pretorius, Marthi A.; Swanepoel, Robert; Venter, Marietjie (Centers for Disease Control & Prevention, 2015-12)
    Old World alphaviruses were identified in 52 of 623 horses with febrile or neurologic disease in South Africa. Five of 8 Sindbis virus infections were mild; 2 of 3 fatal cases involved co-infections. Of 44 Middelburg ...
  • Venter, Marietjie; Steyl, Johan Christian Abraham; Weyer, Jacqueline; Zaayman, Dewald; Paweska, Janusz Tadeusz; Swanepoel, Robert; Human, Stacey; Blumberg, Lucille H.; Leman, Patricia A. (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2010-03)
    No abstract available.
  • Kuhn, Jens H.; Bao, Yımıng M.; Bavari, Sina; Becker, Stephan; Bradfute, Steven; Brauburger, Kristina; Brister, J. Rodney; Bukreyev, Alexander A.; Cai, Yıngyun; Chandran, Kartik; Davey, Robert A.; Dolnik, Olga; Dye, John M.; Enterlein, Sven; Gonzalez, Jean-Paul; Formenty, Pierre; Freiberg, Alexander N.; Hensley, Lisa E.; Hoenen, Thomas; Honko, Anna N.; Ignatyev, Georgy M.; Jahrling, Peter B.; Johnson, Karl M.; Klenk, Hans-Dieter; Kobinger, Gary; Lackemeyer, Matthew G.; Leroy, Eric M.; Lever, Mark S.; Muhlberger, Elke; Netesov, Sergewy V.; Olinger, Gene G.; Palacios, Gustavo; Patterson, Jean L.; Paweska, Janusz Tadeusz; Pitt, Louisa; Radoshitzky, Sheli R.; Ryabchikova, Elena I.; Saphire, Erica Ollmann; Shestopalov, Aleksandr M.; Smither, Sophie J.; Sullivan, Nancy J.; Swanepoel, Robert; Takada, Ayato; Towner, Jonathan S.; Van der Groen, Guido; Volchkov, Viktor E.; Volchkova, Valentina A.; Wahl-Jensen, Victoria; Warren, Travis K.; Warfield, Kelly L.; Weidmann, Manfre; Nichol, Stuart T. (Springer, 2014-05)
    Specific alterations (mutations, deletions, insertions) of virus genomes are crucial for the functional characterization of their regulatory elements and their expression products, as well as a prerequisite for the ...
  • Venter, Marietjie; Swanepoel, Robert (Mary Ann Liebert, 2010)
    West Nile virus (WNV) is widely distributed in South Africa, but since a few cases of neurological disease have been reported from this region, endemic lineage 2 strains were postulated to be of low virulence. Several ...