Browsing Research Articles (Medical Virology) by Author "Ismail, Arshad"

Browsing Research Articles (Medical Virology) by Author "Ismail, Arshad"

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  • Deep sequencing of the HIV‑1 polymerase gene for characterisation of cytotoxic T‑lymphocyte epitopes during early and chronic disease stages 
    Nkone, Paballo; Loubser, Shayne; Quinn, Thomas C.; Redd, Andrew D.; Ismail, Arshad; Tiemessen, Caroline T.; Mayaphi, Simnikiwe Horatious (BMC, 2022-03)
    BACKGROUND : Despite multiple attempts, there is still no effective HIV-1 vaccine available. The HIV-1 polymerase (pol) gene is highly conserved and encodes cytotoxic T-lymphocyte (CTL) epitopes. The aim of the study was ...
  • Emergence and phenotypic characterization of the global SARS-CoV-2 C.1.2 lineage 
    Scheepers, Cathrine; Everatt, Josie; Amoako, Daniel G.; Tegally, Houriiyah; Wibmer, Constantinos Kurt; Mnguni, Anele; Ismail, Arshad; Mahlangu, Boitshoko; Lambson, Bronwen E.; Martin, Darren P.; Wilkinson, Eduan; San, James Emmanuel; Giandhari, Jennifer; Manamela, Nelia; Ntuli, Noxolo; Kgagudi, Prudence; Cele, Sandile; Richardson, Simone I.; Pillay, Sureshnee; Mohale, Thabo; Ramphal, Upasana; Naidoo, Yeshnee; Khumalo, Zamantungwa Thobeka Happiness; Kwatra, Gaurav; Gray, Glenda; Bekker, Linda‑Gail; Madhi, Shabir A.; Baillie, Vicky; Van Voorhis, Wesley C.; Treurnicht, Florette K.; Venter, Marietjie; Mlisana, Koleka; Wolter, Nicole; Sigal, Alex; Williamson, Carolyn; Hsiao, Nei-yuan; Msomi, Nokukhanya; Maponga, Tongai; Preiser, Wolfgang; Makatini, Zinhle; Lessells, Richard; Moore, Penny L.; De Oliveira, Tulio; Von Gottberg, Anne; Bhiman, Jinal N. (Nature Research, 2022-04-08)
    Global genomic surveillance of SARS-CoV-2 has identified variants associated with increased transmissibility, neutralization resistance and disease severity. Here we report the emergence of the PANGO lineage C.1.2, ...
  • Emergence of SARS-CoV-2 Omicron lineages BA.4 and BA.5 in South Africa 
    Tegally, Houriiyah; Moir, Monika; Everatt, Josie; Giovanetti, Marta; Scheepers, Cathrine; Wilkinson, Eduan; Subramoney, Kathleen; Makatini, Zinhle; Moyo, Sikhulile; Amoako, Daniel G.; Baxter, Cheryl; Althaus, Christian L.; Anyaneji, Ugochukwu J.; Kekana, Dikeledi; Viana, Raquel; Giandhari, Jennifer; Lessells, Richard; Maponga, Tongai; Maruapula, Dorcas; Choga, Wonderful; Matshaba, Mogomotsi; Mbulawa, Mpaphi B.; Msomi, Nokukhanya; NGS-SA consortium; Naidoo, Yeshnee; Pillay, Sureshnee; Sanko, Tomasz Janusz; San, James E.; Scott, Lesley; Singh, Lavanya; Magini, Nonkululeko A.; Smith-Lawrence, Pamela; Stevens, Wendy; Dor, Graeme; Tshiabuila, Derek; Wolter, Nicole; Preiser, Wolfgang; Treurnicht, Florette K.; Venter, Marietjie; Chiloane, Georginah; McIntyre, Caitlyn; O’Toole, Aine; Ruis, Christopher; Peacock, Thomas P.; Roemer, Cornelius; Pond, Sergei L. Kosakovsky; Williamson, Carolyn; Pybus, Oliver G.; Bhiman, Jinal N.; Glass, Allison; Martin, Darren P.; Jackson, Ben; Rambaut, Andrew; Laguda-Akingba, Oluwakemi; Gaseitsiwe, Simani; Von Gottberg, Anne; De Oliveira, Tulio; Bester, Armand Phillip; Claassen, Mathilda; Doolabh, Deelan; Mudau, Innocent; Mbhele, Nokuzola; Engelbrecht, Susan; Goedhals, Dominique; Hardie, Diana; Hsiao, Nei-Yuan; Iranzadeh, Arash; Ismail, Arshad; Joseph, Rageema; Maharaj, Arisha; Mahlangu, Boitshoko; Mahlakwane, Kamela; Davis, Ashlyn; Marais, Gert; Mlisana, Koleka; Mnguni, Anele; Mohale, Thabo; Motsatsi, Gerald; Mwangi, Peter; Ntuli, Noxolo; Nyaga, Martin; Olubayo, Luicer; Radibe, Botshelo; Ramphal, Yajna; Ramphal, Upasana; Strasheim, Wilhelmina; Tebeila, Naume; Van Wyk, Stephanie; Wilson, Shannon; Lucaci, Alexander G.; Weaver, Steven; Maharaj, Akhil; Pillay, Yusasha; Davids, Michaela; Mendes, Adriano; Mayaphi, Simnikiwe (Nature Research, 2022-09)
    Three lineages (BA.1, BA.2 and BA.3) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern predominantly drove South Africa’s fourth Coronavirus Disease 2019 (COVID-19) wave. We ...
  • Epidemiological and genomic characterisation of Middelburg and Sindbis alphaviruses identified in horses with febrile and neurological infections, South Africa (2014–2018) 
    Fourie, Isabel; Snyman, Jumari; Williams, J.H. (June Heather); Ismail, Arshad; Jansen van Vuren, Petrus; Venter, Marietjie (MDPI, 2022-09-11)
    Although OldWorld alphaviruses, Middelburg- (MIDV) and Sindbis virus (SINV), have previously been detected in horses and wildlife with neurologic disease in South Africa, the pathogenesis and clinical presentation of ...
  • Multiple novel human norovirus recombinants identified in wastewater in Pretoria, South Africa by next-generation sequencing 
    Mabasa, V.V.; Van Zyl, W.B.; Ismail, Arshad; Allam, Mushal; Taylor, Maureen B.; Mans, Janet (MDPI, 2022-12-07)
    The genogroup II genotype 4 (GII.4) noroviruses are a major cause of viral gastroenteritis. Since the emergence of the Sydney_2012 variant, no novel norovirus GII.4 variants have been reported. The high diversity of ...
  • A novel adenovirus isolated from the Egyptian fruit bat in South Africa is closely related to recent isolates from China 
    Jansen van Vuren, Petrus; Allam, Mushal; Wiley, Michael R.; Ismail, Arshad; Storm, Nadia; Birkhead, Monica; Markotter, Wanda; Palacios, Gustavo; Paweska, Janusz Tadeusz (Nature Publishing Group, 2018-06-25)
    Recently a number of novel adenoviruses have been isolated from diverse bat species and from diverse geographical locations. We describe the isolation of a novel adenovirus (Family Adenoviridae, genus Mastadenovirus) ...
  • Phylogenetic characterisation of the full genome of a Bagaza virus isolate from bird fatalities in South Africa 
    Mendes, Adriano; Lentsoane, Olivia; Allam, Mushal; Khumalo, Zamantungwa Thobeka Happiness; Ismail, Arshad; Coetzer, Jacobus A.W.; Venter, Marietjie (MDPI, 2022-07-05)
    Bagaza virus (BAGV), a member of the Ntaya serogroup in the Flavivirus genus of the Flaviviridae, was isolated from the brain tissue of a Himalayan monal pheasant that died following neurological signs in Pretoria, South ...
  • Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa 
    Viana, Raquel; Moyo, Sikhulile; Amoako, Daniel G.; Tegally, Houriiyah; Scheepers, Cathrine; Althaus, Christian L.; Anyaneji, Ugochukwu J.; Bester, Phillip A.; Boni, Maciej F.; Chand, Mohammed; Choga, Wonderful T.; Colquhoun, Rachel; Davids, Michaela; Deforche, Koen; Doolabh, Deelan; Du Plessis, Louis; Engelbrecht, Susan; Everatt, Josie; Giandhari, Jennifer; Giovanetti, Marta; Hardie, Diana; Hill, Verity; Hsiao, Nei-Yuan; Iranzadeh, Arash; Ismail, Arshad; Joseph, Charity; Joseph, Rageema; Koopile, Legodile; Pond, Sergei L. Kosakovsky; Kraemer, Moritz U.G.; Kuate-Lere, Lesego; Laguda-Akingba, Oluwakemi; Lesetedi-Mafoko, Onalethatha; Lessells, Richard; Lockman, Shahin; Lucaci, Alexander G.; Maharaj, Arisha; Mahlangu, Boitshoko; Maponga, Tongai; Mahlakwane, Kamela; Makatini, Zinhle; Marais, Gert; Maruapula, Dorcas; Masupu, Kereng; Matshaba, Mogomotsi; Mayaphi, Simnikiwe; Mbhele, Nokuzola; Mbulawa, Mpaphi B.; Mendes, Adriano; Mlisana, Koleka; Mnguni, Anele; Mohale, Thabo; Moir, Monika; Moruisi, Kgomotso; Mosepele, Mosepele; Motsatsi, Gerald; Motswaledi, Modisa S.; Mphoyakgosi, Thongbotho; Msomi, Nokukhanya; Mwangi, Peter N.; Naidoo, Yeshnee; Ntuli, Noxolo; Nyaga, Martin; Olubayo, Lucier; Pillay, Sureshnee; Radibe, Botshelo; Ramphal, Yajna; Ramphal, Upasana; San, James E.; Scott, Lesley; Shapiro, Roger; Smith-Lawrence, Pamela; Stevens, Wendy; Strydom, Amy; Subramoney, Kathleen; Tebeila, Naume; Tshiabuila, Derek; Tsui, Joseph; Van Wyk, Stephanie; Weaver, Steven; Wibmer, Constantinos K.; Wilkinson, Eduan; Wolter, Nicole; Zarebski, Alexander E.; Zuze, Boitumelo; Goedhals, Dominique; Preise, Wolfgang; Treurnicht, Florette; Venter, Marietjie; Williamson, Carolyn; Pybus, Oliver G.; Bhiman, Jinal; Glass, Allison; Martin, Darren P.; Rambaut, Andrew; Gaseitsiwe, Simani; Von Gottberg, Anne; De Oliveira, Tulio (Nature Research, 2022-03-24)
    The SARS-CoV-2 epidemic in southern Africa has been characterized by three distinct waves. The first was associated with a mix of SARS-CoV-2 lineages, while the second and third waves were driven by the Beta (B.1.351) ...