Browsing Research Articles (Medical Virology) by Title

Browsing Research Articles (Medical Virology) by Title

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  • Laboratory considerations for reporting cycle threshold value in COVID-19 
    Punchoo, Rivak; Bhoora, Sachin; Bangalee, Avania (International Federation of Clinical Chemistry and Laboratory Medicine, 2022-08)
    The Coronavirus Disease 2019 (COVID-19) pandemic is caused by the SARS-CoV-2 RNA virus. Nucleic acid amplification testing (NAAT) is the mainstay to confirm infection. A large number of reverse transcriptase polymerase ...
  • Large-scale international validation of an indirect ELISA based on recombinant nucleocapsid protein of rift valley fever virus for the detection of IgG antibody in domestic ruminants 
    Paweska, Janusz Tadeusz; Jansen van Vuren, Petrus; Msimang, Veerle; Lo, Modu Moustapha; Thiongane, Yaya; Mulumba-Mfumu, Leopold K.; Mansoor, Alqadasi; Fafetine, Jose M.; Magona, Joseph W.; Boussini, Hiver; Bazanow, Barbara; Wilson, William C.; Pepin, Michel; Unger, H.; Viljoen, Gerrit (MDPI, 2021-08)
    Diagnostic performance of an indirect enzyme-linked immunosorbent assay (I-ELISA) based on a recombinant nucleocapsid protein (rNP) of the Rift Valley fever virus (RVFV) was validated for the detection of the IgG antibody ...
  • Leveraging the Global Influenza Surveillance and Response System for global respiratory syncytial virus surveillance-opportunities and challenges 
    Broor, Shobha; Campbell, Harry; Hirve, Siddhivinayak; Hague, Siri; Jackson, Sandra; Moen, Ann; Nair, Harish; Palekar, Rakhee; Rajatonirina, Soatiana; Smith, Peter G.; Venter, Marietjie; Wairagkar, Niteen; Zambon, Maria; Ziegler, Thedi; Zhang, Wenqing (Wiley Open Access, 2020-11)
    BACKGROUND : Respiratory syncytial virus (RSV)‐associated acute lower respiratory infection is a common cause for hospitalization and hospital deaths in young children globally. There is urgent need to generate evidence ...
  • Leveraging the Road to Health booklet as a unique patient identifier to monitor the prevention of mother-to-child transmission programme 
    Mazanderani, Ahmad Haeri; Sherman, G.G.; Moyo, F.; Goga, Ameena Ebrahim; Feucht, Ute Dagmar (Health and Medical Publishing Group, 2018-09)
    BACKGROUND. Currently there is no unique patient identification system in the South African public health sector. Therefore, routine laboratory data cannot effectively be de-duplicated, thereby hampering surveillance of ...
  • Lineage 2 West Nile virus as cause of fatal neurologic disease in horses, South Africa 
    Venter, Marietjie; Human, Stacey; Zaayman, Dewald; Gerdes, Gertruida Hermanna; Williams, June Heather; Steyl, Johan Christian Abraham; Leman, Patricia A.; Paweska, Janusz Tadeusz; Setzkorn, Hildegard; Rous, Gavin; Murray, Sue; Parker, Rissa; Donnellan, Cynthia Mary Bridget; Swanepoel, Robert (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2009-05-06)
    Serologic evidence suggests that West Nile virus (WNV) is widely distributed in horses in Southern Africa. However, because few neurologic cases have been reported, endemic lineage 2 strains were postulated to be non-pathogenic ...
  • Living donor liver transplant from an HIV-positive mother to her HIV-negative child : opening up new therapeutic options 
    Botha, Jean; Conradie, Francesca; Etheredge, Harriet; Fabian, June; Duncan, Mary; Mazanderani, Ahmad Haeri; Paximadis, Maria; Maher, Heather; Russell Britz; Loveland, Jerome; Strobele, Bernd; Rambarran, Sharan; Mahomed, Adam; Terblanche, Alta J.; Beretta, Marisa; Brannigan, Liam; Pienaar, Michael; Archibald-Durham, Lindsay; Lang, Allison; Tiemessen, Caroline T. (Lippincott Williams and Wilkins, 2018)
    OBJECTIVE : Transplant a liver from an HIV-positive mother to her HIV-negative child to save the child’s life. DESIGN : A unique case of living donor liver transplantation from an HIV-positive mother to her HIV-negative ...
  • Loss of detectability and indeterminate results : challenges facing HIV infant diagnosis in South Africa's expanding ART programme 
    Haeri Mazanderani, Ahmad F.; Du Plessis, Nicolette Marie; Thomas, Winifred Nancy; Venter, E.; Avenant, Theunis Johannes (Health and Medical Publishing Group, 2014-08)
    BACKGROUND. Early infant diagnosis with rapid access to treatment has been found to reduce HIV-associated infant mortality and morbidity considerably. In line with international standards, current South African guidelines ...
  • Loss to follow-up in a community clinic in South Africa – roles of gender, pregnancy and CD4 count 
    Wang, Bingxia; Losina, Elena; Stark, Ruth; Munro, Alison; Walensky, Rochelle P.; Wilke, Marisa; Martin, Desmond J.; Lu, Zhigang; Freedberg, Kenneth A.; Wood, Robin (Health and Medical Publishing Group, 2011-04)
    BACKGROUND: Faith-based organisations have expanded antiretroviral therapy (ART) in community clinics across South Africa. Loss to follow-up (LTFU), however, limits the potential individual and population treatment benefits ...
  • Low seroprevalence of hepatitis E virus in pregnant women in an urban area near Pretoria, South Africa 
    Simani, Omphile E.; Seipone, Tshegofatso P.; Selabe, Gloria; Seheri, L. Mapaseka; Mphahlele, M.; Mayaphi, Simnikiwe Horatious; Steele, A. Duncan (Elsevier, 2022-03)
    OBJECTIVES : Hepatitis E virus (HEV) infection is a globally neglected health problem with a high burden in resource-poor communities. Pregnant women are at increased risk of complications. This pilot study sought to assess ...
  • Lyssaviruses in insectivorous bats, South Africa, 2003–2018 
    Coertse, Jessica; Grobler, Colyn Stefan; Sabeta, Claude Taurai; Seamark, E.C.J.; Kearney, Teresa; Paweska, Janusz Tadeusz; Markotter, Wanda (Centers for Disease Control and Prevention, 2020-12)
    We detected 3 lyssaviruses in insectivorous bats sampled in South Africa during 2003–2018. We used phylogenetic analysis to identify Duvenhage lyssavirus and a potentially new lyssavirus, provisionally named Matlo ...
  • Marburg virus infection in Egyptian rousette bats, South Africa, 2013-2014 
    Paweska, Janusz Tadeusz; Jansen van Vuren, Petrus; Kemp, Alan; Storm, Nadia; Grobbelaar, Antoinette A.; Wiley, Michael R.; Palacios, Gustavo; Markotter, Wanda (Centers for Disease Control and Prevention, 2018)
    We detected a high seroprevalence of Marburg virus (MARV) antibodies in fruit bats in South Africa; 19.1% of recaptured bats seroconverted. The MARV RNA isolated closely resembled the 1975 Ozolin strain. These findings ...
  • Masstag polymerase chain reaction for differential diagnosis of viral hemorrhagic fevers 
    Palacios, Gustavo; Briese, Thomas; Kapoor, Vishal; Jabado, Omar; Liu, Zhiqiang; Venter, Marietjie; Zhai, Junhui; Renwick, Neil; Grolla, Allen; Geisbert, Thomas W.; Drosten, Christian; Towner, Jonathan S.; Ju, Jingyue; Paweska, Janusz Tadeusz; Nichol, Stuart T.; Swanepoel, Robert; Feldmann, Heinz; Jahrling, Peter B.; Lipkin, Ian W. (Centers for Disease Control and Prevention, 2006-04)
    Viral hemorrhagic fevers are associated with high rates of illness and death. Although therapeutic options are limited, early differential diagnosis has implications for containment and may aid in clinical management. We ...
  • Mechanisms of HIV persistence in HIV reservoirs 
    Mzingwane, Mayibongwe L.; Tiemessen, Caroline T. (Wiley, 2017-03)
    The establishment and maintenance of HIV reservoirs that lead to persistent viremia in patients on antiretroviral drugs remains the greatest challenge of the highly active antiretroviral therapy era. Cellular reservoirs ...
  • A metagenomic viral discovery approach identifies potential zoonotic and novel mammalian viruses in Neoromicia bats within South Africa 
    Geldenhuys, Marike; Mortlock, Marinda; Weyer, Jacqueline; Bezuidt, Keoagile Ignatius Oliver; Seamark, E.C.J. (Ernest); Kearney, Teresa; Gleasner, Cheryl; Erkkila, Tracy H.; Cui, Helen; Markotter, Wanda (Public Library of Science, 2018-03-26)
    Species within the Neoromicia bat genus are abundant and widely distributed in Africa. It is common for these insectivorous bats to roost in anthropogenic structures in urban regions. Additionally, Neoromicia capensis ...
  • Microorganisms detected in intussusception cases and controls in children <3 years in South Africa from 2013 to 2017 
    Page, N.A. (Nicola); Netshikweta, Rembuluwani; Tate, Jacqueline E.; Madhi, Shabir A.; Parashar, Umesh D.; Groome, Michelle J. (Oxford University Press, 2023-09)
    A matched case-control evaluated infectious etiologies in children <3 years in post-rotavirus vaccine intussusception surveillance. Adenovirus and adenovirus types C, A, and B were detected more frequently in cases versus ...
  • Microporous polyolefin strands as controlled-release devices for mosquito repellents 
    Mapossa, António Benjamim; Sibanda, Mthokozisi Mayibongwe; Sitoe, Alcides Everildo José; Focke, Walter Wilhelm; Braack, L.E.O.; Ndonyane, Cyril; Mouatcho, Joel Claude; Smart, Jansie; Muaimbo, Herminio; Androsch, Rene; Loots, Mattheus Theodor (Elsevier, 2019-03)
    The main vectors of malaria in Africa, i.e. An. arabiensis, An. gambiae s.s. and An. funestus, are attracted by human foot odour and they tend to bite victims in the ankle area. Hence, affordable mosquito-repellent ...
  • Missed diagnostic opportunities within South Africa's early infant diagnosis program, 2010-2015 
    Mazanderani, Ahmad Haeri; Moyo, Faith; Sherman, Gayle G. (Public Library of Science, 2017-05-11)
    BACKGROUND : Samples submitted for HIV PCR testing that fail to yield a positive or negative result represent missed diagnostic opportunities. We describe HIV PCR test rejections and indeterminate results, and the associated ...
  • Molecular characterisation of enteroviruses and clinical findings from a cluster of paediatric viral meningitis cases in Tshwane, South Africa 2010-2011 
    Wolfaardt, Marianne; Buchner, Ane; Myburgh, Marcelle; Avenant, Theunis Johannes; Du Plessis, Nicolette Marie; Taylor, Maureen B. (Elsevier, 2014-11)
    BACKGROUND : Human enteroviruses (HEVs) are the most common viral pathogen associated with paediatricaseptic meningitis. From October 2010 to February 2011 a cluster of HEV-associated meningitis caseswas identified in ...
  • Molecular characterisation of hepatitis : a virus strains from water sources in South Africa 
    Said, R.; Wolfaardt, Marianne; Taylor, Maureen B. (IWA Publishing, 2014-03)
    Hepatitis A virus (HAV) strains found in selected South African (SA) surface waters were characterised to establish what HAV types are circulating in the environment, thus reflecting circulation in the surrounding ...
  • Molecular detection and characterisation of mumps virus in cerebrospinal fluid in a Gauteng laboratory 
    Brauer, Marieke; Wolfaardt, Marianne; Webber, Lynne M.; Taylor, Maureen B. (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor & Francis Group, 2016)
    The study aimed to determine the presence of mumps virus (MuV) in cerebrospinal fluid (CSF) specimens and to genetically characterise detected MuV strains. A real-time reverse transcription-polymerase chain reaction ...