Browsing Research Articles (Medical Virology) by Title

Browsing Research Articles (Medical Virology) by Title

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  • Deaths associated with respiratory syncytial and influenza viruses among persons greater or equal to 5 years of age in HIV- prevalent area, South Africa, 1998 - 2009 
    Tempia, Stefano; Walaza, Sibongile; Vibound, Cecile; Cohen, Adam L.; Madhi, Shabir A.; Venter, Marietjie; Von Mollendorf, Claire; Moyes, Jocelyn; McAnerney, Johanna M.; Cohen, Cheryl (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2015-04)
    We estimated deaths attributable to influenza and respiratory syncytial virus (RSV) among persons >5 years of age in South Africa during 1998–2009 by applying regression models to monthly deaths and laboratory surveillance ...
  • Deep sequencing of the HIV‑1 polymerase gene for characterisation of cytotoxic T‑lymphocyte epitopes during early and chronic disease stages 
    Nkone, Paballo; Loubser, Shayne; Quinn, Thomas C.; Redd, Andrew D.; Ismail, Arshad; Tiemessen, Caroline T.; Mayaphi, Simnikiwe Horatious (BMC, 2022-03)
    BACKGROUND : Despite multiple attempts, there is still no effective HIV-1 vaccine available. The HIV-1 polymerase (pol) gene is highly conserved and encodes cytotoxic T-lymphocyte (CTL) epitopes. The aim of the study was ...
  • Detection and characterization of an H9N2 influenza A virus in the Egyptian Rousette bat in Limpopo, South Africa 
    Rademan, Rochelle; Geldenhuys, Marike; Markotter, Wanda (MDPI, 2023-02-23)
    In recent years, bats have been shown to host various novel bat-specific influenza viruses, including H17N10 and H18N11 in the Americas and the H9N2 subtype from Africa. Rousettus aegyptiacus (Egyptian Rousette bat) is ...
  • Detection and molecular characterization of urinary tract HIV‑1 populations 
    Mzingwane, Mayibongwe L.; Hunt, G.; Lassauniere, R.; Kalimashe, M.; Bongwe, A.; Ledwaba, J.; Chaisson, R.E.; Martinson, N.; Richter, Karin Louise; Bowyer, S.M.; Tiemessen, Caroline T. (BioMed Central, 2019-09-24)
    BACKGROUND : Identification of all possible HIV reservoirs is an important aspect in HIV eradication efforts. The urinary tract has however not been well studied as a potential HIV reservoir. In this pilot study we ...
  • Detection of Anopheles rivulorum-like, a member of the Anopheles funestus group, in South Africa 
    Mouatcho, Joel Claude; Cornel, Anthony J.; Dahan‑Moss, Yael; Koekemoer, Lizette L.; Coetzee, Maureen; Braack, L.E.O. (BioMed Central, 2018-05-15)
    BACKGROUND : The Anopheles gambiae sensu lato (s.l.) and Anopheles funestus s.l. species complexes contain the most important malaria vectors in Africa. Within the An. funestus group of at least 11 African species, the ...
  • Detection of hypermethylated genes as markers for cervical screening in women living with HIV 
    Kremer, Wieke W.; Van Zummeren, Marjolein; Novianti, Putri W.; Richter, Karin Louise; Verlaat, Wina; Snijders, Peter J.F.; Heideman, Danielle A.M.; Steenbergen, Renske D.M.; Dreyer, Greta; Meijer, Chris J.L.M. (Wiley Open Access, 2018-08)
    INTRODUCTION : To evaluate the performance of hypermethylation analysis of ASCL1, LHX8 and ST6GALNAC5 in physician-taken cervical scrapes for detection of cervical cancer and cervical intraepithelial neoplasia (CIN) grade ...
  • Detection of insect-specific flaviviruses in mosquitoes (Diptera: Culicidae) in northeastern regions of South Africa 
    Guarido, Milehna M.; Govender, Kamini; Riddin, Megan A.; Schrama, Maarten; Gorsich, Erin E.; Brooke, Basil D.; Almeida, Antonio Paulo Gouveia; Venter, Marietjie (MDPI, 2021-10)
    Mosquitoes in the Aedes and Culex genera are considered the main vectors of pathogenic flaviviruses worldwide. Entomological surveillance using universal flavivirus sets of primers in mosquitoes can detect not only ...
  • Detection of potentially pathogenic enteric viruses in environmental samples from Kenya using the bag-mediated filtration system 
    Van Zyl, Walda B.; Zhou, Nicolette A.; Wolfaardt, Marianne; Matsapola, P.N. (Peter); Ngwana, F.B. (Fhatuwani); Symonds, Erin M.; Fagnant-Sperati, Christine S.; Shirai, Jeffry H.; Kossik, Alexandra L.; Beck, Nicola K.; Komen, Evans; Mwangi, Benlick; Nyangao, James; Boyle, David S.; Borus, Peter; Taylor, Maureen B.; Meschke, J. Scott (IWA Publishing, 2019-09)
    Enteric virus environmental surveillance via a highly sensitive method is critical, as many enteric viruses have low infectious doses and can persist in the environment for extended periods. This study determined the ...
  • Detection of Rift Valley fever virus in Aedes (Aedimorphus) durbanensis, South Africa 
    Van den Bergh, Carien; Thompson, P.N. (Peter N.); Swanepoel, Robert; Almeida, Antonio Paulo Gouveia; Paweska, Janusz Tadeusz; Van Vuren, Petrus Jansen; Wilson, William C.; Kemp, Alan; Venter, Estelle Hildegard (MDPI, 2022-01-21)
    Rift Valley fever virus (RVFV) is a mosquito-borne, zoonotic phlebovirus-causing disease in domestic ruminants and humans in Africa, the Arabian Peninsula and some Indian Ocean islands. Outbreaks, characterized by abortion ...
  • Determining the provincial and national burden of influenza-associated severe acute respiratory illness in South Africa using a rapid assessment methodology 
    Murray, Jillian; Cohen, Adam L.; Walaza, Sibongile; Groome, Michelle; Madho, Shabir A.; Variava, Ebrahim; Kahn, Kathleen; Dawood, Halima; Tempia, Stefano; Tshangela, Akhona; Venter, Marietjie; Feikin, Daniel R.; Cohen, Cheryl; Chowell, Gerardo (Public Library of Science, 2015-07-08)
    Local disease burden data are necessary to set national influenza vaccination policy. In 2010 the population of South Africa was 50 million and the HIV prevalence was 11%. We used a previously developed methodology to ...
  • Developing One Health surveillance systems 
    Hayman, David T.S.; Adisasmito, Wiku B.; Almuhairi, Salama; Behravesh, Casey Barton; Bilivogui, Pépé; Bukachi, Salome A.; Casas, Natalia; Becerra, Natalia Cediel; Charron, Dominique F.; Chaudhary, Abhishek; Ciacci Zanella, Janice R.; Cunningham, Andrew A.; Dar, Osman; Debnath, Nitish; Dungu, Baptiste; Farag, Elmoubasher; Gao, George F.; Khaitsa, Margaret; Machalaba, Catherine; Mackenzie, John S.; Markotter, Wanda; Mettenleiter, Thomas C.; Morand, Serge; Smolenskiy, Vyacheslav; Zhou, Lei; Koopmans, Marion (Elsevier, 2023-12)
    The health of humans, domestic and wild animals, plants, and the environment are inter-dependent. Global anthropogenic change is a key driver of disease emergence and spread and leads to biodiversity loss and ecosystem ...
  • Development of a Pan-Filoviridae SYBR green qPCR assay for biosurveillance studies in bats 
    Coertse, Jessica; Mortlock, Marinda; Grobbelaar, Antoinette; Moolla, Naazneen; Markotter, Wanda; Weyer, Jacqueline (MDPI, 2023-04)
    Recent studies have indicated that bats are hosts to diverse filoviruses. Currently, no panfilovirus molecular assays are available that have been evaluated for the detection of all mammalian filoviruses. In this study, ...
  • Development of a respiratory severity score for hospitalized adults in a high HIV-prevalence setting—South Africa, 2010-2011 
    Millman, Alexander J.; Greenbaum, Adena; Walaza, Sibongile; Cohen, Adam L.; Groome, Michelle J.; Reed, Carrie; McMorrow, Meredith; Tempia, Stefano; Venter, Marietjie; Treurnicht, Florette K.; Madhi, Shabir A.; Cohen, Cheryl; Variava, Ebrahim (BioMed Central, 2017-02-02)
    BACKGROUND : Acute lower respiratory tract infections (LRTI) are a frequent cause of hospitalization and mortality in South Africa; however, existing respiratory severity scores may underestimate mortality risk in ...
  • Diagnosis and monitoring of HIV infection 
    Glass, Allison J. (Medpharm Publications, 2006-09)
    The latest statistics indicate that the number of people infected with human immunodeficiency virus type 1 (HIV-1) worldwide is 40.3 million, 25.8 million of whom live in sub-Saharan Africa. In 2004, 29.5% of South African ...
  • Diarrhoeal diseases in Soweto, South Africa, 2020 : a cross-sectional community survey 
    Johnstone, Siobhan L.; Page, Nicola Anne; Thomas, Juno; Madhi, Shabir A.; Mutevedzi, Portia; Myburgh, Nellie; Herrera, Carlos; Groome, Michelle J. (BioMed Central, 2021-07-20)
    BACKGROUND : In South Africa, there are limited data on the burden of diarrhoea at a community level, specifically in older children and adults. This community survey estimated rates of and factors associated with diarrhoea ...
  • Distribution of influenza virus types by age using case-based global surveillance data from twenty-nine countries, 1999-2014 
    Caini, Saverio; Spreeuwenberg, Peter; Kusznierz, Gabriela F.; Rudi, Juan Manuel; Owen, Rhonda; Pennington, Kate; Wangchuk, Sonam; Gyeltshen, Sonam; Ferreira de Almeida, Walquiria Aparecida; Henriques, Claudio Maierovitch Pessanha; Njouom, Richard; Vernet, Marie-Astrid; Fasce, Rodrigo A.; de Mora, Domenica; De Lozano, Celina; Zambon, Maria; Pebody, Richard; Castillo, Leticia; Clara, Alexey W.; Matute, Maria Luisa; Kosasih, Herman; Nurhayati; Puzelli, Simona; Rizzo, Caterina; Kadjo, Herve A.; Daouda, Coulibaly; Kiyanbekova, Lyazzat; Ospanova, Akerke; Mott, Joshua A.; Emukule, Gideon O.; Heraud, Jean-Michel; Razanajatovo, Norosoa Harline; Barakat, Amal; El Falaki, Fatima; Huang, Sue Q.; Lopez, Liza; Balmaseda, Angel; Moreno, Brechla; Rodrigues, Ana Paula; Guiomar, Raquel; Ang, Li Wei; Lee, Vernon Jian Ming; Venter, Marietjie; Cohen, Cheryl; Badur, Selim; Ciblak, Meral A.; Mironenko, Alla; Holubka, Olha; Bresee, Joseph; Brammer, Lynnette; Hoang, Phuong Vu Mai; Quynh Le, Mai Thi; Fleming, Douglas; Seblain, Clotilde El-Guerche; Schellevis, François; Paget, John; Global Influenza B Study group (BioMed Central, 2018-06-08)
    BACKGROUND : Influenza disease burden varies by age and this has important public health implications. We compared the proportional distribution of different influenza virus types within age strata using surveillance ...
  • Diverse norovirus genotypes identified in sewage-polluted river water in South Africa 
    Mans, Janet; Netshikewta, Rembuluwani; Magwalivha, Mpho; Van Zyl, Walda B.; Taylor, Maureen B. (Cambridge University Press, 2012-03-21)
    This study aimed to assess norovirus (NoV) contamination and genotype diversity in surface water in Gauteng, South Africa. Between January 2008 and December 2010, three rivers, namely Klip, Suikerbosrant, and Rietspruit ...
  • Diverse sapovirus genotypes identified in children hospitalised with gastroenteritis in selected regions of South Africa 
    Murray, Tanya Y.; Nadan, Sandrama; Page, Nicola Anne; Taylor, Maureen B. (Elsevier, 2016-03)
    BACKGROUND : Sapoviruses (SaVs) are recognised as causative agents of gastroenteritis worldwide. How-ever, data on the genetic diversity of this virus in Africa are lacking, particularly in the form of currentlong-term ...
  • Drug-resistant tuberculosis in pet ring-tailed Lemur, Madagascar 
    LaFleur, Marni; Reuter, Kim E.; Hall, Michael B.; Rasoanaivo, Hoby H.; McKernan, Stuart; Ranaivomanana, Paulo; Michel, Anita Luise; Rabodoarivelo, Marie Sylvianne; Iqbal, Zamin; Rakotosamimanana, Niaina; Lapierre, Simon Grandjean (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2021-03)
    We diagnosed tuberculosis in an illegally wild-captured pet ring-tailed lemur manifesting lethargy, anorexia, and cervical lymphadenopathy. Whole-genome sequencing confirmed the Mycobacterium tuberculosis isolate belonged ...
  • Economic evaluation of rotavirus vaccination in children aged under five years in South Africa 
    Mohy, Ahmed; Page, N.A. (Nicola); Boyce, Welekazi; Gomez, Jorge A. (Springer, 2023-11)
    BACKGROUND AND OBJECTIVE Evidence on the economic value of rotavirus vaccines in middle-income countries is limited. We aimed to model the implementation of three vaccines (human rotavirus, live, attenuated, oral vaccine ...