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Browsing Research Articles (Anatomy) by UP Author "Bester, Megan Jean"
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Pereira, Andreia S.P.; Bester, Megan Jean; Soundy, Puffy; Apostolides, Zeno
(Springer, 2015-11)
Extracts prepared from the roots of Pelargonium sidoides (DC) are commercially available
for the treatment of respiratory related conditions. Recently, a commercial radix mother
tincture of this plant was shown to have ...
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Arbi, Sandra; Bester, Megan Jean; Pretorius, Liselle; Oberholzer, Hester Magdalena
(Taylor and Francis, 2021)
The aim of this study was to identify cardiovascular effects of relevant concentrations of Cd and Hg alone and in combination as a mixture in water. This was achieved by administering to male Sprague–Dawley rats via gavage ...
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Janse van Rensburg, Maxine; Bester, Megan; Van Rooy, Mia-Jeanne; Oberholzer, Hester Magdalena
(Sage, 2023-08)
Cardiovascular diseases (CVD) are a common global cause of death and are therefore a major health concern. Inhaled or ingested environmental heavy metals contribute to the development of CVD. The aim of this study was to ...
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Draper, Maxine; Bester, Megan; Van Rooy, Mia-Jeanne; Oberholzer, Hester Magdalena
(Taylor and Francis, 2023)
Exposure to environmental metal pollutants is linked to oxidative stress and the subsequent development of neurological disease. In this study, the effects of copper, manganese, and mercury, were evaluated at X100 the World ...
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Draper, Maxine; Bester, Megan Jean; Van Rooy, Mia-Jeanne; Oberholzer, H.M.
(Routledge, 2023)
The rise in respiratory disease has been attributed to an increase in environmental pollution. Heavy metals contribute to environmental contamination via air, water, soil and food. The effects of atmospheric exposure to ...
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Malan, Melissa; Serem, June Cheptoo; Bester, Megan Jean; Neitz, Albert Walter Herman; Gaspar, Anabella Regina Marques
(Wiley, 2016-01)
Antimicrobial peptides (AMPs) are small, cationic peptides that possess a large spectrum of bioactivities, including antimicrobial, anti-inflammatory and antioxidant activities. Several AMPs are known to inhibit ...
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Pereira, Andreia S.P.; Bester, Megan Jean; Soundy, Puffy; Apostolides, Zeno
(Taylor and Francis, 2016-09)
CONTEXT : Pelargonium sidoides DC (Geraniaceae) is an important medicinal plant indigenous to South Africa and Lesotho. Previous studies have shown root extracts rich in polyphenolic compounds with antibacterial, antiviral ...
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Pardau, Madelein D.; Pereira, Andreia S.P.; Apostolides, Zeno; Serem, June Cheptoo; Bester, Megan Jean
(Royal Society of Chemistry, 2017-12)
Ilex guayusa tea preparations are now commercially available as Runa tea. Little is known regarding the antioxidant and anti-inflammatory bioactivities of this tea. The I. guayusa teas had a total polyphenolic content ...
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Sakr, Samar; Hassanien, Hanan; Bester, Megan Jean; Arbi, Sandra; Sobhy, Azza; El Negris, Heba; Steenkamp, Vanessa
(Royal Society of Chemistry, 2018-03)
The aim of this study was to evaluate the protective effect of folate against methomyl-induced toxicity on the kidneys and testes of male rats. Adult male albino rats were divided into four groups; Group I served as the ...
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Ibrahim, Mohammed Auwal; Serem, June Cheptoo; Abdullahi, Aliyu Dantani; Aminu, Suleiman; Aliyu, Abubakar Babando; Musa, Aliyu Muhammad; Musa, Bashir; Bester, Megan; Gaspar, A.R.M. (Anabella Regina Marques)
(Springer, 2023-04)
The multifactorial nature of type 2 diabetes mellitus (T2DM) has driven a need to discover multifunctional antidiabetic peptides preferably from functional food sources for possible application as antidiabetic supplements. ...
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Shelembe, Jeremiah Sijubo; Cromarty, Allan Duncan; Bester, Megan Jean; Minnaar, Amanda; Duodu, Kwaku Gyebi
(Wiley-Blackwell, 2012-03)
Freeze-dried aqueous phenolic extracts with possible application as natural antioxidant functional food ingredients were prepared from marama bean seed coats by extracting with water. Phenolic acids, flavonoids and ...
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Oberholzer, Hester Magdalena; Van der Schoor, Ciska; Taute, Helena; Bester, Megan Jean
(Wiley, 2015-08)
Exposure to drugs during pregnancy is a major concern, as some teratogenic compounds
can influence normal foetal development. Although the use of drugs during pregnancy
should generally be avoided, exposure of the ...
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Ibrahim, Mohammed Auwal; Serem, June Cheptoo; Bester, Megan Jean; Gaspar, Anabella Regina Marques
(Elsevier, 2020-10)
Type 2 diabetes is a multifactorial disease and drugs with multifunctional properties are required. The peptide, SQSPA, was reported to be a potent and gastrointestinally stable α-glucosidase inhibitory peptide. In this ...
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Apea-Bah, Franklin B.; Minnaar, Amanda; Bester, Megan Jean; Duodu, Kwaku Gyebi
(Elsevier, 2014-08)
The effect of compositing red non-tannin sorghum with cream-coloured cowpea and porridge preparation
on phenolic profile and radical scavenging activity was studied. A maize–soybean composite
porridge representing a ...
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Taute, Helena; Bester, Megan Jean; Gaspar, Anabella Regina Marques
(Wiley, 2019-04)
Antimicrobial peptides (AMPs), Os and Os‐C, have been identified as multifunctional peptides with antibacterial, antiendotoxin, and anti‐inflammatory properties. For further development of Os and Os‐C as therapeutic peptides, ...
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Shelembe, Jeremiah Sijubo; Cromarty, Allan Duncan; Bester, Megan Jean; Minnaar, Amanda; Duodu, Kwaku Gyebi
(Wiley- Blackwell, 2014-02)
The effect of extraction under acidic condition (pH 2) on phenolic compounds and
antioxidant potential of aqueous extracts fromcondensed tannin sorghumbran was
investigated. The protective effect of extracts prepared ...
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Van der Schoor, Ciska; Oberholzer, Hester Magdalena; Bester, Megan Jean; Van Rooy, Mia-Jeanne
(Informa Healthcare, 2014-12)
Sibutramine is used in the treatment of obesity due to its ability to influence feelings of hunger and satiety by
inhibiting the re-uptake of serotonin and noradrenalin in the central nervous system (CNS). Sibutramine ...
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Apea-Bah, Franklin B.; Serem, June Cheptoo; Bester, Megan Jean; Duodu, Kwaku Gyebi; Beta, Trust
(Elsevier, 2021-12)
The effect of simulated in vitro upper gut digestion on the phenolic composition and antioxidant properties of processed cowpea beans was studied. The samples comprised four cowpea cultivars: a cream, brownish-cream and ...
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Da Silva, A.A. (Andrea Almeida); Bester, Megan Jean; Pretorius, Etheresia
(Elsevier, 2007-01)
Cannabis and Mandrax abuse is unique to South Africa; and most research has focused on the socio-economic impact rather than the adverse effects on the developing brain. Therefore, the aim of this study is to determine the ...
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Venter, Chantelle; Oberholzer, Hester Magdalena; Cummings, Franscious Riccardo; Bester, Megan Jean
(Wiley, 2017-08)
Heavy metal pollution has increased in the last decades. Water sources are contaminated and human exposure is often long term exposure to variable amounts of different metals. In this study, male Sprague-Dawley rats were ...