The famous premise of John Polkinghorne, ‘epistemology models ontology’, has been assessed
in this article. It is interpreted that its logic is based on a linear trajectory of knowledge → being.
Polkinghorne places much emphasis on the fact that he pursues a ‘bottom-up’ approach, that
is, an inductive way of going about with reality. He opts for a ‘critical realist’ view of reality
that leads him to interpret indeterminacy (Heisenberg) as a sign of actual ontological openness
to the future and not primarily as an epistemological deficit. He applies subsequently the
doctrine of the Trinity as a hermeneutical tool to understand reality. The author argues that
Polkinghorne is inconsistent in this venture and that he should consider a multidimensional
approach, where epistemology and ontology model each other mutually, that is, knowledge
↔ being. In order to acknowledge the stratification of reality and the pluriformity of
epistemologies, it is suggested that a rather ‘constructive-realist’ approach would serve better
the theology of Polkinghorne; this is a shift from epistemology to hermeneutics.