Guideline : Appropriate use of tigecycline

Show simple item record Brink, Andries J. Bizos, D. Boffard, Kenneth D. Feldman, Charles Grolman, D.C. Pretorius, Jan P. Richards, Guy A. Senekal, M. Steyn, E. Welkovic, N. 2011-06-13T06:24:55Z 2011-06-13T06:24:55Z 2010-06
dc.description.abstract INTRODUCTION: Tigecycline, the first of a new class of antibiotics, the glycylcyclines, was licensed in South Africa for the parenteral treatment of adult patients with complicated intraabdominal infections (cIAIs) and complicated skin and softtissue infections (cSSTIs). METHODS: A multidisciplinary meeting representative of the Association of Surgeons of South Africa, the Critical Care Society of Southern Africa, the Federation of Infectious Diseases Societies of Southern Africa, the South African Thoracic Society and the Trauma Society of South Africa was held to draw up a national guideline for the appropriate use of tigecycline. Background information reviewed included randomised controlled trials, other relevant publications and local antibiotic susceptibility patterns. The initial document was drafted at the meeting. Subsequent drafts were circulated to members of the working group for modification. OUTPUT: The guideline addresses several important aspects of the new agent, summarising key clinical data and highlighting important considerations with the use of the drug. The recommendations in this guideline are based on currently available scientific evidence together with the consensus opinion of the authors. CONCLUSION: This statement was written out of concern regarding the widespread misuse of antibiotics. Its primary intention is to facilitate heterogeneous use of antibiotics as a component of antibiotic stewardship and to highlight the appropriate use of tigecycline in particular. en_US
dc.description.sponsorship Sponsored through an unrestricted educational grant from Wyeth. en_US
dc.identifier.citation Brink, AJ, Bizos, D, Boffard, KD, Feldman, C, Grolman, DC, Pretorius, J, Richards, GA, Senekal, M, Steyn, E & Welkovic, N 2010, 'Guideline : Appropriate use of tigecycline', South African Medical Journal, vol. 100, no. 6, pp. 388-394. [] en_US
dc.identifier.issn 0256-9574 (print)
dc.identifier.issn 2078-5135 (online)
dc.language.iso en en_US
dc.publisher Health and Medical Publishing Group en_US
dc.rights Health and Medical Publishing Group en_US
dc.subject Tigecycline en_US
dc.subject Antibiotics en_US
dc.subject Glycylcyclines en_US
dc.subject Adult patients en_US
dc.subject Complicated intraabdominal infections (cIAIs) en_US
dc.subject Complicated skin and softtissue infections (cSSTIs) en_US
dc.title Guideline : Appropriate use of tigecycline en_US
dc.type Article en_US

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