PET/CT scanning with a high HIV/AIDS prevalence

Show simple item record Warwick, J.M. Sathekge, Mike Machaba 2011-03-08T06:24:16Z 2011-03-08T06:24:16Z 2011-04
dc.description.abstract Positron emission tomography (PET) with [F-18]-fluoro-deoxy-glucose (FDG) has a well established and growing role in the management of most lymphomas. The interpretation of FDG PET scans in HIV positive patients is however challenging. This is largely due to scan changes giving a higher likelihood of false positive studies from both the direct effects of HIV and its treatment, and related to secondary HIV-related pathology. There is currently a need for further clinical research to evaluate to contribution of FDG PET in the management of HIV positive patients with lymphoma. In this paper existing studies related to FDG PET scanning in HIV positive patients will be reviewed, and potential pitfalls will be identified. These pitfalls can be avoided to some extent by the interpreter having a good clinical knowledge of the individual patients’ condition, and an awareness of known scintigraphic patterns that can occur in these patients. PET remains a sensitive tool for the localisation of pathology, however when the exact nature of lesions has a direct bearing on patient management lesions need to be biopsied where possible. FDG PET can be particularly useful for the characterisation of brain lesions suspected to be related to primary central nervous system lymphoma. en_US
dc.identifier.citation Warwick JM & Sathekge MM, 'PET/CT scanning with a high HIV/AIDS prevalence', Transfusion and Apheresis Science, vol.44, no. 2, pp. 167-172. (2011), doi:10.1016/j.transci.2011.01.014 en_US
dc.identifier.issn 1473-0502
dc.identifier.other 10.1016/j.transci.2011.01.014
dc.language.iso en en_US
dc.publisher Elsevier en_US
dc.rights © 2011 Elsevier Ltd. All rights reserved. en_US
dc.subject Positron emission tomography (PET) en_US
dc.subject HIV/AIDS en_US
dc.subject.lcsh Lymphomas -- Treatment
dc.subject.lcsh Tomography, Emission
dc.title PET/CT scanning with a high HIV/AIDS prevalence en_US
dc.type Postprint Article en_US

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