Cytotoxicity activity of isolated compounds from Elaeodendron transvaalense ethanol extract

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dc.contributor.author Tshikalange, T.E. (Thilivhali Emmanuel)
dc.contributor.author Hussein, Ahmed A.
dc.date.accessioned 2011-01-10T13:04:29Z
dc.date.available 2011-01-10T13:04:29Z
dc.date.issued 2010-08
dc.description.abstract Five known compounds, four triterpenoids and 4’ –O- methylepigallocatechin 5 were isolated from Elaeodendron transvaalense bark ethanol extract. This plant is traditionally used in Southern Africa for the treatment of various ailments including sexually associated diseases. Cytotoxicity of the isolated compounds was determined using XTT colorimetric assay against Vero and MCF-7 breast cancer cell lines. Compound 1, 3, 4, 5 showed weaker activities with the IC50 ranging from 66.6 to over 100.00 g/ml in both cell lines. Compound 2 exhibited a good cytotoxicity activity IC50 value of 25.1 for Vero cells and 19.4 for breast cancer cell line. en
dc.identifier.citation Tshikalange, TE & Hussein, A 2010, 'Cytotoxicity activity of isolated compounds from Elaeodendron transvaalense ethanol extract', Journal of Medicinal Plant Research, vol. 4, no. 16, pp. 1695-1697. [www.academicjournals.org/JMPR] en
dc.identifier.issn 1996-0875
dc.identifier.uri http://hdl.handle.net/2263/15586
dc.language.iso en en_US
dc.publisher Academic Journals en_US
dc.rights © 2010 Academic Journals en
dc.subject Elaeodendron transvaalense en
dc.subject Cytotoxicity activity en
dc.subject Triterpenoid en
dc.title Cytotoxicity activity of isolated compounds from Elaeodendron transvaalense ethanol extract en
dc.type Article en


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