Abstract:
Five known compounds, four triterpenoids and 4’ –O- methylepigallocatechin 5 were isolated from
Elaeodendron transvaalense bark ethanol extract. This plant is traditionally used in Southern Africa for
the treatment of various ailments including sexually associated diseases. Cytotoxicity of the isolated
compounds was determined using XTT colorimetric assay against Vero and MCF-7 breast cancer cell
lines. Compound 1, 3, 4, 5 showed weaker activities with the IC50 ranging from 66.6 to over 100.00 g/ml
in both cell lines. Compound 2 exhibited a good cytotoxicity activity IC50 value of 25.1 for Vero cells and
19.4 for breast cancer cell line.
