Antifungal activity of leaf extracts from South African trees against plant pathogens

Show simple item record Mahlo, S.M. (Salome Mamokone) McGaw, Lyndy Joy Eloff, Jacobus Nicolaas 2010-12-20T09:14:38Z 2010-12-20T09:14:38Z 2010-12
dc.description.abstract The antifungal activity of acetone, methanol, hexane and dichloromethane leaf extracts of six plant species (Bucida buceras, Breonadia salicina, Harpephyllum caffrum, Olinia ventosa, Vangueria infausta and Xylotheca kraussiana) were evaluated for antifungal activity against seven plant pathogenic fungal species (Aspergillus niger, Aspergillus parasiticus, Colletotricum gloeosporioides, Penicillium janthinellum, Penicillium expansum, Trichoderma harzianum and Fusarium oxysporum). These plant species were selected from 600 evaluated inter alia, against two animal fungal pathogens. All plant extracts were active against the selected plant pathogenic fungi. Of the six plant species, B. buceras had the best antifungal activity against four of the fungi, with minimum inhibitory concentration (MIC) values as low as 0.02 mg/ml and 0.08 mg/ml against P. expansum, P. janthinellum, T. harzianum and F. oxysporum. Some of the plant extracts had moderate to low activity against other fungi, indicating that the activity is not based on a general metabolic toxicity. P. janthinellum, T. harzianum and F. oxysporum were the most sensitive fungal species, with a mean MIC of 0.28 mg/ml, while the remaining four fungi were more resistant to the extracts tested, with mean MICs above 1 mg/ml. The number of active compounds in the plant extracts was determined using bioautography with the listed plant pathogens. No active compounds were observed in some plant extracts with good antifungal activity as a mixture against the fungal plant pathogens, indicating possible synergism between the separated metabolites, B. salicina and O. ventosa were the most promising plant species, with at least three antifungal compounds. Leaf extracts of different plant species using different methods (acetone, hexane, DCM and methanol) had antifungal compounds with the same Rf values. The same compounds may be responsible for activity in extracts of different plant species. Based on the antifungal activity, crude plant extracts may be a cost effective way of protecting crops against fungal pathogens. Because plant extracts contain several antifungal compounds, the development of resistant pathogens may be delayed. en_US
dc.description.sponsorship National Research Foundation (NRF). University of Pretoria. Claude Leon Foundation for a Postdoctoral Fellowship. en_US
dc.identifier.citation Mahlo, SM, McGaw, LJ & Eloff, JN 2010, 'Antifungal activity of leaf extracts from South African trees against plant pathogens', Crop Protection, vol. 29, no. 12, pp. 1529-1533. [] en_US
dc.identifier.issn 0261-2194
dc.identifier.other 10.1016/j.cropro.2010.08.015
dc.identifier.other 55952645400
dc.identifier.other 7005589445
dc.language.iso en en_US
dc.publisher Elsevier en_US
dc.rights Elsevier en_US
dc.subject Antifungal activity en_US
dc.subject Plant pathogens en_US
dc.subject Minimum inhibitory concentration en_US
dc.subject Bioautography en_US
dc.subject Breonadia salicina en_US
dc.title Antifungal activity of leaf extracts from South African trees against plant pathogens en_US
dc.type Postprint Article en_US

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