The Brody effect induced by premature ventricular complexes in the ovine heart

Show simple item record Ker, James A. Webb, E.C. (Edward Cottington) Van Papendorp, D.H. (Dirk Hermanus), 1949- 2010-12-09T13:49:25Z 2010-12-09T13:49:25Z 2009-12
dc.description.abstract The QRS response of the electrocardiogram to bleeding has been a source of interest to the physiologist for more than a century. Studies in the dog, cat and chicken have shown a reduction in QRS amplitude in response to bleeding. This effect has been explained by the so-called Brody effect, in which the intraventricular mass of blood acts as a conducting medium, augmenting radial conduction, thus resulting in the subsequent reduction in QRS amplitude in conditions where the intraventricular mass of blood is reduced. The aim of this study was to evaluate whether the Brody effect will be present in the ovine heart and, furthermore, to evaluate if the right and left ventricles will demonstrate the same QRS change if the Brody effect is indeed present. This study clearly demonstrated that the Brody effect is present in the ovine heart. Furthermore, two unique aspects emanating from this study are firstly the fact that this is the first study to show that premature ventricular complexes are able to induce the Brody effect and, secondly that there is a very clear difference in the response of the right and the left ventricles when the Brody effect is induced in the ovine heart. en_US
dc.identifier.citation Ker, J, Webb, EC & Van Papendorp, 2010, 'The Brody effect induced by premature ventricular complexes in the ovine heart', Onderstepoort Journal of Veterinary Research, vol. 76. no. 4, pp. 443-448. [] en_US
dc.identifier.issn 0030-2465
dc.language.iso en en_US
dc.publisher Agricultural Research Council, ARC-OVI and the University of Pretoria en_US
dc.rights © 2010. The Authors. Licensee: OpenJournals Publishing. This work is licensed under the Creative Commons Attribution License. en_US
dc.subject Brody effect en_US
dc.subject Ovine heart en_US
dc.subject QRS amplitude en_US
dc.subject Premature ventricular complex en_US
dc.subject.lcsh Heart -- Ventricles
dc.subject.lcsh Electrocardiography en
dc.subject.lcsh Heart -- Diseases -- Research en
dc.subject.lcsh Ventricular remodeling en
dc.title The Brody effect induced by premature ventricular complexes in the ovine heart en_US
dc.type Article en_US

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