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dc.contributor.author | Stegmann, George F.![]() |
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dc.date.accessioned | 2010-10-27T07:24:44Z | |
dc.date.available | 2010-10-27T07:24:44Z | |
dc.date.issued | 2010 | |
dc.description.abstract | The cardiovascular effects of non-abdominal and abdominal surgery during isoflurane anaesthesia (A-group) or isoflurane anaesthesia supplemented with either epidural ropivacaine (AR-group; 0.75 % solution, 0.2 m /kg) or morphine (AM-group; 0.1 mg/kg diluted in saline to 0.2m /kg) were evaluated in 28 healthy pigs with a mean body weight of 30.3 kg SD ± 4.1 during surgical devascularisation of the liver. Anaesthesia was induced with the intramuscular injection of midazolam (0.3 mg/kg) and ketamine (10 mg/kg). Anaesthesia was deepened with intravenous propofol to enable tracheal intubation and maintained with isoflurane on a circle rebreathing circuit. The vaporiser was set at 2.5%for the A-group and 1.5%for the AR- and AM-groups. Differences between treatment groups were not statistically significant (P>0.05) for any of the variables. Differences betweenAMand AR-groups were marginally significant heart rate (HR) (P = 0.06) and mean arterial blood pressure (MAP) (P = 0.08). Within treatment groups, differences for the A-group were statistically significant (P<0.05) between non-abdominal and abdominal surgery for HR, systolic blood pressure, diastolic blood pressure (DIA) andMAP.Within the AM-group differences were statistically significant (P < 0.05) for DIA and MAP, and within the AR group differences for all variables were not statistically significant (P > 0.05). It was concluded that in isoflurane-anaesthetised pigs, the epidural administration of ropivacaine decreased heart rate and improved arterial blood pressure during surgery. | en |
dc.identifier.citation | Stegmann, GF 2010, 'Cardiovascular effects of epidural morphine or ropivacaine in isoflurane-anaesthetised pigs during surgical devascularisation of the liver', Journal of the South African Veterinary Association, vol. 81, no. 3, pp. 143–147. [http://www.journals.co.za/ej/ejour_savet.html] | en |
dc.identifier.issn | 0038-2809 | |
dc.identifier.uri | http://hdl.handle.net/2263/15080 | |
dc.language.iso | en | en |
dc.publisher | South African Veterinary Association | en |
dc.rights | South African Veterinary Association | en |
dc.subject | Anaesthesia | en |
dc.subject | Cardiovascular effects | en |
dc.subject | Epidural anaesthesia | en |
dc.subject | Morphine | en |
dc.subject | Pigs | en |
dc.subject | Ropivacaine | en |
dc.subject.lcsh | Veterinary anesthesia -- South Africa | en |
dc.subject.lcsh | Anesthesiology -- Research | en |
dc.title | Cardiovascular effects of epidural morphine or ropivacaine in isoflurane-anaesthetised pigs during surgical devascularisation of the liver | en |
dc.type | Article | en |