Adaptations in the glucose metabolism of procyclic Trypanosoma brucei isolates from tsetse flies and during differentiation of bloodstream forms

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Authors

Van Grinsven, Koen W.A.
Van den Abbeele, Jan
Van den Bossche, Peter
Van Hellemond, Jaap J.
Tielens, Aloysius G.M.

Journal Title

Journal ISSN

Volume Title

Publisher

American Society for Microbiology

Abstract

Procyclic forms of Trypanosoma brucei isolated from the midguts of infected tsetse flies, or freshly transformed from a strain that is close to field isolates, do not use a complete Krebs cycle. Furthermore, short stumpy bloodstream forms produce acetate and are apparently metabolically preadapted to adequate functioning in the tsetse fly.

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Keywords

Adaptations, Glucose metabolism

Sustainable Development Goals

Citation

Van Grinsven, KWA, Van den Abbeele, J, Van den Bossche, P, Van Hellemond, JJ & Tielens, AGM 2009, 'Adaptations in the glucose metabolism of procyclic Trypanosoma brucei Isolates from tsetse flies and during differentiation of bloodstream forms', Eukaryotic cell, vol. vol. 8, no. 8, pp. 1307-1311. [http://ec.asm.org/]