Evaluation of a rapid immunodiagnostic test kit for detection of African lyssaviruses from brain material
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Date
Authors
Markotter, Wanda
York, D.
Sabeta, Claude Taurai
Shumba, W.
Zulu, Gugulethu Cynthia
Le Roux, Kevin
Nel, Louis Hendrik
Journal Title
Journal ISSN
Volume Title
Publisher
Agricultural Research Council, ARC-OVI and the University of Pretoria
Abstract
A rapid immunodiagnostic test kit was evaluated against a selection of isolates of lyssavirus genotypes occurring in Africa. The test was carried out in parallel comparison with the fluorescent antibody test (FAT) and isolates representing previously established phylogenetic groups from each genotype were included. The specificity of the rapid immunodiagnostic test compared favourably with the FAT and was found to detect all representatives of genotypes 1, 2, 3 and 4 in brain samples of either field cases or suckling mouse brain inoculates.
Description
Keywords
Lyssaviruses, Rapid test kit
Sustainable Development Goals
Citation
Markotter, W, York, D, Sabeta, CT, Shumba, W, Zulu, G, Le Roux, K & Nel, LH 2009, 'Evaluation of a rapid immunodiagnostic test kit for detection of African lyssaviruses from brain material', Onderstepoort Journal of Veterinary Research, vol. 76, no. 2, pp. 257-262. [http://www.journals.co.za/ej/ejour_opvet.html]