Dehydrobrachylaenolide : an eudesmanetype sesquiterpene lactone

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Authors

Rademeyer, Melanie
Van Heerden, Fanie R.
Van der Merwe, Marina M.

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International Union of Crystallography

Abstract

The three-ring eudesmanolide, C15H16O3, is a natural product isolated from Dicoma anomala Sond. (Asteraceae). The compound contains an endo–exo cross conjugated methylenecyclohexenone ring with an envelope conformation transfused with cyclohexane and trans-annelated with an - methylene -lactone. The absolute structure was assigned by optical rotation measurements compared to those from the synthetic compound with known stereochemistry. The crystal packing is consolidated by C—H...O interactions.

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Single-crystal X-ray study, T = 150 K, Mean (C–C) = 0.002 A°, R factor = 0.033, wR factor = 0.095, Data-to-parameter ratio = 14.1

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Citation

Rademeyer, M, Van Heerden, FR & Van Der Merwe, MM 2009, 'Dehydrobrachylaenolide: an eudesmanetype sesquiterpene lactone', Acta Crystallographica, E65, p. 196. [http://journals.iucr.org/e/journalhomepage.html]