Cleft soft palate reconstruction : prospective study on infection and antibiotics

Show simple item record Myburgh, H.P. Butow, Kurt-Wilhelm 2009-08-25T07:29:34Z 2009-08-25T07:29:34Z 2009
dc.description.abstract The aim of this prospective study was to identify possible pathogenic organisms associated with wound complications in the form of wound infections, wound breakdown and the formation of oro-nasal fistulas. The organisms’ resistance profile to antibiotics was also evaluated. This prospective study consisted of the evaluation of the intra-oral microbiological profile of 100 babies with soft palate cleft deformities peri-operatively. A wide spectrum of pathogenic organisms from the upper aero-digestive track was isolated, as well as a group of organisms that originated from the colon/perineum. The latter organisms were mostly associated with postoperative complications. The antibiotic resistance profile showed a high resistance to commonly used antibiotics such as ampicillin, amoxycillin-clavulanic acid, and first- and second-generation cephalosporins. The resistance profile of the organisms needs to be reassessed and appropriate antibiotics must be used in combination with an antimicrobial mouth rinse. en_US
dc.identifier.citation Myburgh, HP & Butow, KW, Cleft soft palate reconstruction : prospective study on infection and antibiotics, Int J Oral Maxillofac Surg (2009), doi:10.1016/j.ijom.2009.04.022 en_US
dc.identifier.issn 0901-5027
dc.identifier.other 10.1016/j.ijom.2009.04.022
dc.language.iso en en_US
dc.publisher Elsevier en_US
dc.rights Elsevier en_US
dc.subject Cleft soft palate en_US
dc.subject Microbiology en_US
dc.subject Anti-biotics en_US
dc.subject Postoperative complications en_US
dc.subject.lcsh Palate, Soft
dc.subject.lcsh Palate -- Surgery -- South Africa
dc.subject.lcsh Surgical wound infections -- South Africa
dc.subject.lcsh Pathogenic microorganisms
dc.subject.lcsh Antibiotics
dc.title Cleft soft palate reconstruction : prospective study on infection and antibiotics en_US
dc.type Postprint Article en_US

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