The antigenicity of Clostridium botulinum type C toxin administered per os

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Date

Authors

Jansen, B.C.
Knoetze, P.C.
Visser, Fleur

Journal Title

Journal ISSN

Volume Title

Publisher

Pretoria : Government Printer

Abstract

Large quantities of toxoid given to rabbits per os did not elicit a primary immune response. Toxin absorbed through the intestinal wall of guinea-pigs and toxoided produced an anamnestic response on injection into basically-immune rabbits, but had no effect on fully susceptible rabbits. By dosing sufficient toxin or toxoid per os to basically-immune rabbits anamnestic responses could be produced.

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Keywords

Veterinary medicine, Veterinary reports, South Africa (SA), Botulism, Guinea pigs, Guineapigs, Rabbits

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Citation

Jansen, BC, Knoetze, PC & Visser, F 1970, 'The antigenicity of Clostridium botulinum type C toxin administered per os', Onderstepoort Journal of Veterinary Research, vol. 70, no. 3, pp. 169-171.