African swine fever virus isolate, Georgia, 2007

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Authors

Rowlands, Rebecca J.
Michaud, Vincent
Heath, Livio Edward
Hutchings, Geoff
Oura, C.A.L.
Vosloo, Wilna
Dwarka, Rahana M.
Onashvili, Tinatin
Albina, Emmanuel
Dixon, Linda K.

Journal Title

Journal ISSN

Volume Title

Publisher

Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention

Abstract

African swine fever (ASF) is widespread in Africa but is rarely introduced to other continents. In June 2007, ASF was confirmed in the Caucasus region of Georgia, and it has since spread to neighboring countries. DNA fragments amplified from the genome of the isolates from domestic pigs in Georgia in 2007 were sequenced and compared with other ASF virus (ASFV) isolates to establish the genotype of the virus. Sequences were obtained from 4 genome regions, including part of the gene B646L that encodes the p72 capsid protein, the complete E183L and CP204L genes, which encode the p54 and p30 proteins and the variable region of the B602L gene. Analysis of these sequences indicated that the Georgia 2007 isolate is closely related to isolates belonging to genotype II, which is circulating in Mozambique, Madagascar, and Zambia. One possibility for the spread of disease to Georgia is that pigs were fed ASFV-contaminated pork brought in on ships and, subsequently, the disease was disseminated throughout the region.

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Keywords

African swine fever, Virus, Hemorrhagic fever, Domestic pig (Sus domesticus)

Sustainable Development Goals

Citation

Rowlands, RJ, Michaud, V, Heath, L, Hutchings, G, Oura, C, Vosloo, W, Dwarka, R, Onashvili, T, Albina, E & Dixon, LK 2008, ‘African swine fever virus isolate, Georgia, 2007’, Emerging Infectious Diseases, vol. 14, no. 12, pp. 1870-1874. [www.cdc.gov/eid]