Browsing by Author "Yacqub-Usman, Kiren"

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Apoptosis in cancer cells is induced by alternative splicing of hnRNPA2/B1 through splicing of Bcl-x, a mechanism that can be stimulated by an extract of the South African medicinal plant, Cotyledon orbiculata

Makhafola, Tshepiso Jan; Mbele, Mzwandile; Yacqub-Usman, Kiren; Hendren, Amy; Haigh, Daisy Belle; Blackley, Zoe; Meyer, Mervin; Mongan, Nigel Patrick; Bates, David Owen; Dlamini, Zodwa (Frontiers Media, 2020-10)

Alternative splicing is deregulated in cancer and alternatively spliced products can be linked to cancer hallmarks. Targeting alternative splicing could offer novel effective cancer treatments. We investigated the effects ...

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