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Browsing by Author "Kumar, Pradeep"
Now showing items 1-7 of 7
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Pantshwa, Jonathan M.; Rhoda, Khadija; Clift, Sarah Jane; Pradeep, Priyamvada; Choonara, Yahya E.; Kumar, Pradeep; Du Toit, Lisa C.; Penny, Clement; Pillay, Viness; Pillay, Viness (MDPI Publishing, 2018-10-04)The present study aimed to design and develop a nanocomposite drug delivery system employing an antineoplastic-loaded antibody functionalized nanomicelle encapsulated within a Chitosan–Poly(vinylpyrrolidone)–Poly(N-iso ...
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Ngwuluka, Ndidi C.; Choonara, Yahya E.; Modi, Girish; Du Toit, Lisa C.; Kumar, Pradeep; Meyer, Leith Carl Rodney; Snyman, Tracy; Pillay, Viness (Hindawi Publishing, 2017)One approach for delivery of narrow absorption window drugs is to formulate gastroretentive drug delivery systems. This study was undertaken to provide insight into in vivo performances of two gastroretentive systems (PXLNET ...
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Khan, Zaheeda; Govender, Mershen; Indermun, Sunaina; Kumar, Pradeep; Choonara, Yahya E.; Du Toit, Lisa C.; Meyer, Leith Carl Rodney; Pillay, Viness (Elsevier, 2018-06)Chronotherapeutic disorders such as hypertension, cardiovascular disease and asthma commonly involve the use of controlled zero-order release formulations. Ideally, the required drug should be released at predetermined ...
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Reddy, Deshika; Choonara, Yahya E.; Kumar, Pradeep; Govender, Mershen; Indermun, Sunaina; Du Toit, Lisa C.; Meyer, Leith Carl Rodney; Pillay, Viness (Elsevier, 2017-02)The purpose of this study was to design and evaluate the performance of an Ultra-fast Disintegrating Wafer (U-D-WAF) loaded with highly water soluble diphenhydramine hydrochloride (DPH) through the oramucosa of the Large ...
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Fears, Robin; Akutsu, Hidenori; Alentajan-Aleta, Lara Theresa; Caicedo, Andres; De Carvalho, Antonio Carlos Campos; Colic, Miodrag; Cornish, Jillian; Cossu, Giulio; Debre, Patrice; Dierckxsens, Geoffrey; El-Badri, Nagwa; Griffin, George; Hsieh, Patrick Chingo-Ho; Inamdar, Maneesha S.; Kumar, Pradeep; Abraham, Consuelo Macias; Maciulaitis, Romaldas; Mahtab, Mamun Al; O’Brien, Fergal J.; Pepper, Michael Sean; Ter Meulen, Volker (Cell Press, 2021-08-10)Regenerative medicine has great potential. The pace of scientific advance is exciting and the medical opportunities for regeneration and repair may be transformative. However, concerns continue to grow, relating to problems ...
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Mashingaidze, Felix; Choonara, Yahya E.; Kumar, Pradeep; Du Toit, Lisa C.; Maharaj, Vinesh J.; Buchmann, Eckhart; Pillay, Viness (Elsevier, 2016-04)This paper explores the potential of polyethylene glycol enclatherated pectin-mucin (PEGencl- PEC:MUC) submicron matrices (SMMs) as an intravaginal drug delivery system capable of delivering an anti-HIV-1 agent (zidovudine; ...
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Submicron matrices embedded in a polymeric caplet for extended intravaginal delivery of Zidovudine Mashingaidze, Felix; Choonara, Yahya E.; Kumar, Pradeep; Du Toit, Lisa C.; Maharaj, Vinesh J.; Buchmann, Eckhart; Pillay, Viness (Springer, 2017-11)In this study, an intravaginal delivery system able to deliver an anti-HIV-1 agent for the purpose of potentially reducing HIV-1 transmission acting over an extended duration was successfully formulated. This delivery ...
Now showing items 1-7 of 7