Browsing by UP Author "Wessels, Pieter Frederik"

Browsing by UP Author "Wessels, Pieter Frederik"

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  • Anticoagulation therapy in diabetic patients 
    Wessels, Pieter Frederik (Clinics Cardiv, 2012-03)
    Diabetic patients have a high risk of developing arterial disease (coronary artery, cerebrovascular and peripheral arterial disease) and are therefore often given antiplatelet therapy. Although only retrospective studies ...
  • COVID-19-associated coagulopathy and antithrombotic agents—lessons after 1 year 
    Leentjens, Jenneke; Van Haaps, Thijs F.; Wessels, Pieter Frederik; Schutgens, Roger E.G.; Middeldorp, Saskia (Elsevier, 2021-07)
    COVID-19 is associated with a high incidence of thrombotic complications, which can be explained by the complex and unique interplay between coronaviruses and endothelial cells, the local and systemic inflammatory response, ...
  • A descriptive investigation of the ultrastructure of fibrin networks in thrombo-embolic ischemic stroke 
    Pretorius, Etheresia; Swanepoel, A.C. (Albe Carina); Oberholzer, Hester Magdalena; Van der Spuy, Wendy Jeannette; Duim, Wiebren; Wessels, Pieter Frederik (Springer, 2011-05)
    Stroke is one of the leading causes of death worldwide. Formation of a fibrin clot is controlled by a group of tightly regulated plasma proteases and cofactors and a change in the fibrin fiber formation causes an alteration ...
  • Hypercoagulability in COVID-19 
    Wessels, Pieter Frederik (South African Heart Association, 2020-11)
    COVID-19 is associated with a hypercoagulable state that may present as pulmonary thrombosis, pulmonary embolism, and venous and arterial thrombosis. Suggested pathogenesis include direct infection of the endothelial cell ...
  • Patient blood management : a solution for South Africa 
    Thomson, J.; Hofmann, A.; Barrett, C.A.; Beeton, A.; Bellairs, G.R.M.; Boretti, L.; Coetzee, M.J.; Farmer, S.; Gibbs, M.W.; Gombotz, H.H.; Hilton, C.; Kassianides, C.; Louw, V.J.; Lundgren, C.; Mahlangu, J.N.; Noel, C.B.; Rambiritch, V.; Schneider, F.; Verburgh, E.; Wessels, P.-L.; Wessels, Pieter Frederik; Wise, R.; Shander, A. (Health and Medical Publishing Group, 2019-07)
    For more than 70 years the default therapy for anaemia and blood loss was mostly transfusion. Accumulating evidence demonstrates a significant dose-dependent relationship between transfusion and adverse outcomes. This and ...
  • Thromboprophylaxis in spinal surgery : a survey of current practice in South Africa 
    Jacobs, H.W. (Hans); Zondagh, Ian; Wessels, Pieter Frederik (South African Orthopaedic Association, 2017)
    BACKGROUND : Patients undergoing spinal surgery are at risk of developing venous thromboembolism (VTE) because of co-morbidities and immobilisation, but the morbidity of bleeding and haematoma formation complicates prophylaxis. ...
  • Towards perioperative point-of-care viscoelastic testing 
    Wessels, Pieter Frederik (Medpharm Publications, 2023)
    No abstract available.
  • Venous thromboembolism : prophylactic and therapeutic practice guideline 
    Jacobson, B.F.; Louw, S.; Buller, H.; Mer, M.; De Jong, P.R.; Rowji, P.; Schapkaitz, E.; Adler, D.; Beeton, A.; Hsu, H-C.; Wessels, Pieter Frederik; Haas, S. (Health and Medical Publishing Group, 2013-04)
    BACKGROUND: Pharmacological prophylactic anticoagulation in many countries, including South Africa, is under-prescribed. This has resulted in unacceptable rates of morbidity and mortality. METHOD: The Southern African ...
  • Venous thromboembolism in pregnancy 
    Wessels, Pieter Frederik (Health and Medical Publishing Group, 2019-11)
    Pregnancy-related venous thromboembolic events are important preventable causes of morbidity and mortality in South Africa. All pregnant patients should be evaluated for thrombotic risk at different stages of their pregnancy ...
  • Venous thrombosis in the patient with cancer 
    Wessels, Pieter Frederik (Open Journals Systems, 2012)
    The relationship between cancer and thrombosis has been known for many years. Thrombotic risk is increased in the patient with cancer, and the diagnosis of venous thromboembolism at the time that a malignancy presents ...