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Browsing by UP Author "Verschoor, J.A. (Jan Adrianus), 1953-"
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Ranchod, Heena; Ndlandla, Fortunate; Lemmer, Yolandy; Beukes, Mervyn; Niebuhr, Johann; Al-Dulayymi, Juma; Wemmer, Susan; Fehrsen, Jeanni; Baird, Mark S.; Verschoor, J.A. (Jan Adrianus), 1953-
(Public Library of Science, 2018-08-09)
Mycolic acids (MA) are major, species-specific lipid components of Mycobacteria and
related genera. In Mycobacterium tuberculosis, it is made up of alpha-, methoxy- and keto-
MA, each with specific biological functions ...
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Driver, Kathy (Cathryn Helena Stanford); Balogun, Mohammed Olusegun; Toschi, Gianna; Verschoor, J.A. (Jan Adrianus), 1953-; Baird, Mark S.; Pilcher, Lynne A.
(Elsevier, 2010-02)
A new method for the stereoselective synthesis of the (R,R)-b-hydroxy-a-alkyl fatty acid fragment of
mycolic acids, via an asymmetric anti-aldol reaction is reported. The ‘mycolic acid motif’ fragment was prepared in three ...
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Verschoor, J.A. (Jan Adrianus), 1953-; Bragg, R.R. (Robert Richard); Coetzee, L.; Verwoerd, Daniel Wynand
(Published by the Agricultural Research Council, Onderstepoort Veterinary Institute, 1996)
Infectious coryza remains an important disease in the poultry industry despite the long-term and widespread
use of vaccines against its causative agent, Haemophilus paragallinarum, in South Africa.
In order to detect ...
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Verschoor, J.A. (Jan Adrianus), 1953-; Bornman, L.; Vermeulen, N.M.J.; Bigalke, R.D.
(Published by the Government Printer, Pretoria., 1987)
Certain species of Geigeria contain sesquiterpene lactones which cause vomiting disease in sheep. Dihydrogriesenin (DHG), a sesquiterpene lactone from G. aspera, contains an α-methylene function which can spontaneously ...
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Groenewald, Wilma; Baird, Mark S.; Verschoor, J.A. (Jan Adrianus), 1953-; Minnikin, David E.; Croft, Anna K.
(Elsevier, 2014-05)
Mycolic acids are structural components of the mycobacterial cell wall that have been implicated in thepathogenicity and drug resistance of certain mycobacterial species. They also offer potential in areassuch as rapid ...
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Verschoor, J.A. (Jan Adrianus), 1953-; Bragg, R.R. (Robert Richard); Coetzee, L.; Verwoerd, Daniel Wynand
(Published by the Agricultural Research Council, Onderstepoort Veterinary Institute, 1997)
Haemophilus paragallinarum causes infectious coryza in poultry, and a panel of monoclonal antibodies (Mabs) were established, which detect surface antigens of this bacterium. It was postulated that these Mabs could be used ...
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Verschoor, J.A. (Jan Adrianus), 1953-; Bragg, R.R. (Robert Richard); Purdan, G.; Coetzee, L.; Verwoerd, Daniel Wynand
(Published by the Agricultural Research Council, Onderstepoort Veterinary Institute, 1995)
Strain 0083 and two field isolates of H. paragallinarum were previously converted into NAD-independent
organisms by the use of crude DNA extractions from naturally occurring NAD-independent H. paragallinarumisolates. Two ...
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Ozoemena, Kenneth I.; Mathebula, N.S. (Nsovo Samuel); Pillay, Jeseelan; Toschi, Gianna; Verschoor, J.A. (Jan Adrianus), 1953-
(Royal Society of Chemistry, 2010)
The integrity and properties of mycolic acid (MA) antigens integrated into a self-assembled monolayer (SAM) of N-(2-mercaptoethyl)octadecanamide, (MEODA), on a gold electrode have
been interrogated using cyclic voltammetry ...
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Verschoor, J.A. (Jan Adrianus), 1953-; Patterton, H.G.; Potgieter, D.J.J.; Bigalke, R.D.
(Published by The Government Printer, Pretoria, 1985)
Pachystigma pygmaeum is one of several species of rubiaceous plants which cause delayed heart failure among ruminants after their ingestion at relatively high doses. Using guinea-pigs for toxicity determinations, we were ...
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Al Dulayymi, Juma'a R.; Baird, Mark S.; Roberts, Evan; Deysel, Madrey; Verschoor, J.A. (Jan Adrianus), 1953-
(Elsevier, 2007-03-19)
Mycolic acids (Scheme 1) are major constituents of the cell envelope of Mycobacterium
tuberculosis and other mycobacteria, some of which are pathogenic to animals and
humans.1 and 2 Their presence is thought to be linked ...
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O’Kennedy, Martha M.; Abolnik, Celia; Smith, Tanja; Motlou, Thopisang; Goosen, Kruger; Sepotokele, Kamogelo M.; Roth, Robyn; Du Preez, Ilse; Truyts, Alma; Stark, Hester C.; Magwaza, Martin; Mahanjana, Osborn; Verschoor, J.A. (Jan Adrianus), 1953-; Moore, Penny L.; Lemmer, Yolandy
(Elsevier, 2023-03)
The outbreak of the SARS-CoV-2 global pandemic heightened the pace of vaccine development with various vaccines being approved for human use in a span of 24 months. The SARS-CoV-2 trimeric spike (S) surface glycoprotein, ...
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Semete, B.; Booysen, L.I.J.; Kalombo, Lonji; Venter, Jacobus D.; Katata, L.; Ramalapa, B.; Verschoor, J.A. (Jan Adrianus), 1953-; Swai, H.
(Elsevier, 2010-12)
Nanoparticulate drug delivery systems offer great promise in addressing challenges of drug toxicity, poor bioavailability and non-specificity for a number of drugs. Much progress has been reported for nano drug delivery ...
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Prozesky, Leon; Verschoor, J.A. (Jan Adrianus), 1953-; Neitz, Albert Walter Herman; Viljoen, Gerrit Johannes; Vermeulen, N.M.J.; Oberem, P.T.; Bezuidenhout, J. Dürr; Putterill, John Fraser; Visser, L.; Bigalke, R.D.
(Published by The Government Printer, Pretoria, 1985)
The isolation of Cowdria ruminantium by means of wheat germ lectin affinity chromatography as described
in this paper permits the recovery of partially purified viable organisms under mild conditions in short time.
These ...
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Neitz, Albert Walter Herman; Verschoor, J.A. (Jan Adrianus), 1953-; Viljoen, G.J.; Bezuidenhout, J. Dürr; Oberem, P.T.; Putterill, John Fraser; Visser, L.; Vermeulen, N.M.J.; Bigalke, R.D.
(Published by the Government Printer, Pretoria., 1986)
The isolation of Cowdria ruminantium by means of Percoll density gradient centrifugation permits the recovery of partially purified viable populations of the organism possessing distinctly different densities. These ...
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Verschoor, J.A. (Jan Adrianus), 1953-; Bragg, R.R. (Robert Richard); Coetzee, L.; Verwoerd, Daniel Wynand
(Published by the Agricultural Research Council, Onderstepoort Veterinary Institute, 1993)
A total of 27 different isolates of Haemophilus paragallinarum were made from chickens between June
1991 and December 1992. All of these isolates were examined by ELISA, by means of a locally produced
panel of three ...
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Smet, Muriel; Pollard, Charlotte; De Beuckelaer, Ans; Van Hoecke, Lien; Vander Beken, Seppe; De Koker, Stefaan; Al Dulayymi, Juma’a R.; Huygen, Kris; Verschoor, J.A. (Jan Adrianus), 1953-; Baird, Mark S.; Grooten, Johan
(Wiley, 2016-09)
Mycolic acids (MAs) are highly hydrophobic long-chain α-alkyl β-hydroxy fatty acids present in the cell wall of
Mycobacterium tuberculosis (Mtb) as a complex mixture of molecules with a common general structure but with ...
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Lemmer, Yolandy; Kalombo, Lonji; Pietersen, Ray-Dean; Jones, Arwyn T.; Semete-Makokotlela, Boitumelo; Van Wyngaardt, Sandra; Ramalapa, B.; Stoltz, Anton Carel; Baker, Bienyameen; Verschoor, J.A. (Jan Adrianus), 1953-; Swai, H.; De Chastellier, Chantal
(Elsevier, 2015-08)
The appearance of drug-resistant strains of Mycobacterium tuberculosis (Mtb) poses a great challenge to the development
of novel treatment programmes to combat tuberculosis. Since innovative nanotechnologiesmight ...
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Verschoor, J.A. (Jan Adrianus), 1953-; University of Pretoria, Dept. of Biochemistry.
(University of Pretoria, 2012-03-09)
It is all about bringing scientific discovery in the medical biotechnology field to the bedside of patients
who need it, for which an institute is required to transfer the technology from the academic environment
into ...
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Verschoor, J.A. (Jan Adrianus), 1953-; Bragg, R.R. (Robert Richard); Coetzee, L.; Verwoerd, Daniel Wynand
(Published by the Agricultural Research Council, Onderstepoort Veterinary Institute, 1993)
Atypical Haemophilus paragallinarum have been isolated from both laying hens and broilers suffering
from typical symptoms of infectious coryza in South Africa. Re-inoculation of these bacteria into SPF
chickens resulted ...
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Verschoor, J.A. (Jan Adrianus), 1953-; Potgieter, D.J.J.; Bigalke, R.D.
(Published by The Government Printer, Pretoria, 1984)
Pachystigma pygmaeum is a rubiaceous plant which causes heart failure after ingestion by ruminants.
Isolation or characterization of a toxic entity has hitherto been unsuccessful. Extraction of the plant material with
water ...