Browsing by UP Author "Ueckermann, Veronica"

Browsing by UP Author "Ueckermann, Veronica"

Sort by: Order: Results:

  • Aberrant innate immune profile associated with COVID-19 mortality in Pretoria, South Africa 
    Van der Mescht, Mieke Adri; De Beer, Zelda; Steel, Helen C.; Anderson, Ronald; Masenge, Andries; Moore, Penny L.; Bastard, Paul; Casanova, Jean-Laurent; Abdullah, Fareed; Ueckermann, Veronica; Rossouw, Theresa M. (Elsevier, 2024-09)
    The African continent reported the least number of COVID-19 cases and deaths of all the continents, although the exact reasons for this are still unclear. In addition, little is known about the immunological profiles ...
  • Acute intermittent porphyria mimicking Guillain–Barré syndrome in a HIV patient 
    Soma, Prashilla; Ueckermann, Veronica; Sasikumar, S.S. (Sunayana); Mashoeshoe, K.S. (Sam) (Elsevier, 2016-01)
    The diagnosis of porphyria remains challenging as the condition is characterized by a myriad of clinical and biochemical features. More importantly, an acute attack is associated with increased morbidity and mortality. ...
  • Ad26.COV2.S breakthrough infections induce high titers of neutralizing antibodies against Omicron and other SARS-CoV-2 variants of concern 
    Kitchin, Dale; Richardson, Simone I.; Van der Mescht, Mieke Adri; Motlou, Thopisang; Mzindle, Nonkululeko; Moyo-Gwete, Thandeka; Makhado, Zanele; Ayres, Frances; Manamela, Nelia P.; Spencer, Holly; Lambson, Bronwen; Oosthuysen, Brent; Kaldine, Haajira; Du Pisanie, Marizane; Mennen, Mathilda; Skelem, Sango; Williams, Noleen; Ntusi, Ntobeko A.B.; Burgers, Wendy A.; Gray, Glenda G.; Bekker, Linda-Gail; Boswell, Michael T.; Rossouw, Theresa M.; Ueckermann, Veronica; Moore, Penny L. (Cell Press, 2022-03-15)
    The Janssen (Johnson & Johnson) Ad26.COV2.S non-replicating viral vector vaccine has been widely deployed for COVID-19 vaccination programs in resource-limited settings. Here we confirm that neutralizing and binding ...
  • Adapted full-face snorkel masks as an alternative for COVID-19 personal protection during aerosol generating procedures in South Africa 
    Herselman, Ronel; Lalloo, Vidya; Ueckermann, Veronica; Van Tonder, Daniel Johannes; De Jager, Edwin John; Spijkerman, Sandra; Van der Merwe, Wanda; Du Pisane, Marizane; Hattingh, Fanie; Stanton, David; Hofmeyr, Ross (Elsevier, 2021-12)
    INTRODUCTION : SARS-CoV-2 has resulted in increased worldwide demand for personal protective equipment (PPE). With pressure from ongoing epidemic and endemic episodes, we assessed an adapted snorkel mask that provides full-face ...
  • Adjunctive use of statins for COVID-19 
    Sathekge, Mike Machaba; Byttebier, Geert; De Spiegeleer, Bart; Saxberg, Bo; Ueckermann, Veronica; Belmans, Luc; Alexander, Myriam; Fedson, David (MDPI, 2021-04-01)
    The interaction between obesity, cardiometabolic disorders and COVID-19 represents a syndemic that requires both social intervention and a multipharmacological approach. The risks associated with diabetes, obesity and ...
  • Antibody-dependent cellular cytotoxicity against SARS-CoV-2 Omicron sub-lineages is reduced in convalescent sera regardless of infecting variant 
    Richardson, Simone I.; Kgagudi, Prudence; Manamela, Nelia P.; Kaldine, Haajira; Venter, Elizabeth M.; Pillay, Thanusha; Lambson, Bronwen E.; Van der Mescht, Mieke Adri; Hermanus, Tandile; Balla, Sashkia R.; De Beer, Zelda; De Villiers, Talita R.; Bodenstein, Annie; Van den Berg, Gretha; Du Pisanie, Marizane; Burgers, Wendy A.; Ntusi, Ntobeko A.B.; Abdullah, Fareed; Ueckermann, Veronica; Rossouw, Theresa; Boswell, Michael T.; Moore, Penny L. (Cell Press, 2023-01)
    The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.4 and BA.5 variants caused major waves of infections. Here, we assess the sensitivity of BA.4 to binding, neutralization, and antibodydependent cellular ...
  • The association between elevated troponin levels and all cause 30 day mortality in critically ill patients seen at an Academic Hospital – a prospective cohort study 
    Joseph, Darren; Ker, James A.; Rheeder, Paul; Ueckermann, Veronica (University of Leicester, 2017-03-07)
    PURPOSES : Elevated cardiac troponins have been shown to be associated with mortality in critical care, but its utility is not well established, especially in the setting of renal failure. This study aimed to examine the ...
  • Case study : a novel use for faecal microbial transplantation 
    Ueckermann, Veronica; Francis, E.W. (NISC (Pty) Ltd, Medpharm Publications, and Informa UK Limited, 2019)
    Faecal microbiota transplantation (FMT) refers to the infusion of faeces from a healthy donor, into the gastrointestinal tract of a recipient patient. There is considerable evidence for the efficacy of FMT for the ...
  • A challenging case of hypercalcaemia 
    Ueckermann, Veronica (Health and Medical Publishing Group, 2013)
    Hypercalcaemia is not uncommon in clinical practice. The majority of cases are accounted for by hyperparathyroidism and malignancy. The patient discussed below presented with an unusual case of hypercalcaemia.
  • Characteristics and outcomes of patients admitted to a tertiary academic hospital in Pretoria with HIV and severe pneumonia : a retrospective cohort study 
    Ueckermann, Veronica; Janse van Rensburg, Luricke; Pannell, N.; Ehlers, Marthie Magdaleen (BMC, 2022-06-15)
    BACKGROUND : Human immunodeficiency virus (HIV) contributes significantly to morbidity and mortality in South Africa. Pneumonia and opportunistic infections remain a major cause for hospital admission among those living ...
  • Comparison of platelet-and endothelial-associated biomarkers of disease activity in people hospitalized with Covid-19 with and without HIV co-infection 
    Van der Mescht, Mieke Adri; Steel, Helen C.; De Beer, Zelda; Abdullah, Fareed; Ueckermann, Veronica; Anderson, Ronald; Rossouw, Theresa (Frontiers Media, 2023-08-14)
    INTRODUCTION : SARS-CoV-2 elicits a hyper-inflammatory response that contributes to increased morbidity and mortality in patients with COVID-19. In the case of HIV infection, despite effective anti-retroviral therapy, ...
  • Comparison of targeted metagenomics and IS-Pro methods for analysing the lung microbiome 
    Goolam Mahomed, Tanweer; Peters, Remco P.H.; Pretorius, G.H.J.; Mahomed, A. Goolam; Ueckermann, Veronica; Kock, Marleen M.; Ehlers, Marthie Magdaleen (BioMed Central, 2021-08-18)
    BACKGROUND : Targeted metagenomics and IS-Pro method are two of the many methods that have been used to study the microbiome. The two methods target different regions of the 16 S rRNA gene. The aim of this study was to ...
  • COVID-19 severity and in-hospital mortality in an area with high HIV prevalence 
    Boswell, Michael; Maimela, T.C.R. (Tshegofatso); Hameiri-Bowen, Dan; Riley, George; Malan, Albertus; Steyn, Nickietta; Nolutshungu, Nomonde; De Villiers, Talita R.; De Beer, Zelda; Mathabathe, John; Tshabalala, Khanyisile; Abdullah, Fareed; Ramlall, Rajiev; Heystek, Marthinus J.; Basu, Debashis; Rheeder, Paul; Ueckermann, Veronica; Van Hougenhouck-Tulleken, Wesley G. (AOSIS, 2023-01-27)
    BACKGROUND : HIV infection causes immune dysregulation affecting T-cell and monocyte function, which may alter coronavirus disease 2019 (COVID-19) pathophysiology. OBJECTIVES : We investigated the associations among ...
  • Cross-reactive neutralizing antibody responses elicited by SARS-CoV-2 501Y.V2 (B.1.351) 
    Moyo‑Gwete, Thandeka; Madzivhandila, Mashudu; Makhado, Zanele; Ayres, Frances; Mhlanga, Donald; Oosthuysen, Brent; Lambson, Bronwen E.; Kgagudi, Prudence; Tegally, Houriiyah; Iranzadeh, Arash; Doolabh, Deelan; Tyers, Lynn; Chinhoyi, Lionel R.; Mennen, Mathilda; Skelem, Sango; Marais, Gert; Wibmer, Constantinos K.; Bhiman, Jinal N.; Ueckermann, Veronica; Rossouw, Theresa M.; Boswell, Michael T.; De Oliveira, Tulio (Massachusetts Medical Society, 2021-06)
    No abstract available.
  • Decline in antibody responses to SARS-CoV-2 post-vaccination poses a risk to health care workers 
    Worsley, Catherine M.; Van der Mescht, Mieke Adri; Hoffmann, Daniel; Meyer, Pieter Willem Adriaan; Ueckermann, Veronica; Rossouw, Theresa M. (Elsevier, 2022-09)
    No abstract available.
  • Decreased severity of disease during the first global Omicron variant COVID-19 outbreak in a large hospital in Tshwane, South Africa 
    Abdullah, Fareed; Myers, J.; Basu, Debashis; Tintinger, Gregory; Ueckermann, Veronica; Mathebula, M.; Ramlall, R.; Spoor, S.; De Villiers, T.; Van der Walt, Z.; Cloete, Jeane; Soma-Pillay, Priya; Rheeder, Paul; Paruk, Fathima; Engelbrecht, Adel; Lalloo, Vidya; Myburg, M.; Kistan, J.; Van Hougenhouck-Tulleken, Wesley G.; Boswell, Michael T.; Gray, G.; Welch, R.; Blumberg, Lucille Hellen; Jassat, W. (Elsevier, 2022-03)
    INTRODUCTION : The coronavirus disease 2019 (COVID-19) first reported in Wuhan, China in December 2019 is a global pandemic that is threatening the health and wellbeing of people worldwide. To date there have been more ...
  • Despite delayed kinetics, people living with HIV achieve equivalent antibody function after SARS-CoV-2 infection or vaccination 
    Motsoeneng, Boitumelo M.; Manamela, Nelia; Kaldine, Haajira; Kgagudi, Prudence; Hermanus, Tandile; Ayres, Frances; Makhado, Zanele; Moyo-Gwete, Thandeka; Van der Mescht, Mieke Adri; Abdullah, Fareed; Boswell, Michael; Ueckermann, Veronica; Rossouw, Theresa; Madhi, Shabir A.; Moore, Penny L.; Richardson, Simone I. (Frontiers Media, 2023-08-03)
    The kinetics of Fc-mediated functions following SARS-CoV-2 infection or vaccination in people living with HIV (PLWH) are not known. We compared SARS-CoV-2 spike-specific Fc functions, binding, and neutralization in ...
  • Detection of neutralizing antibodies in COVID-19 patients from Steve Biko Academic Hospital Complex : a pilot study 
    Kgatle, Mankgopo; Chalwe, Joseph Musonda; Van der Westhuizen, Donald; Xu, Shuting; Damane, Botle Precious; Mathebela, Precious; Ueckermann, Veronica; Mayaphi, Simnikiwe; Rodrigues, Hosana Gomes; Moura-Alves, Pedro; Ndlovu, Honest; Mzizi, Yonwaba; Zongo, Lusanda; Hairwadzi, Henry; Vorster, Mariza; Zeevaart, Jan Rijn; Sathekge, Mike Machaba (MDPI, 2023-07-03)
    A correlation between neutralization activity after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination and protection against coronavirus disease 2019 (COVID-19) has been demonstrated by several ...
  • The lung microbiome in HIV‑positive patients with active pulmonary tuberculosis 
    Ueckermann, Veronica; Lebre, Pedro H.; Geldenhuys, Janri; Hoosien, Ebrahim; Cowan, Don A.; Janse van Rensburg, Luricke; Ehlers, Marthie Magdaleen (Nature Research, 2022-05-28)
    Tuberculosis poses one of the greatest infectious disease threats of our time, especially when associated with human immunodeficiency virus (HIV) infection. Very little data is available on the lung microbiome in pulmonary ...
  • Lung microbiome of stable and exacerbated COPD patients in Tshwane, South Africa 
    Goolam Mahomed, Tanweer; Peters, Remco P.H.; Allam, M.; Ismail, A.; Mtshali, S.; Goolam Mahomed, A.; Ueckermann, Veronica; Kock, Marleen M.; Ehlers, Marthie Magdaleen (Nature Research, 2021-10)
    Chronic obstructive pulmonary disease (COPD) is characterised by the occurrence of exacerbations triggered by infections. The aim of this study was to determine the composition of the lung microbiome and lung virome in ...