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Browsing by UP Author "Sagar, Travers"
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Sagar, Travers; Kasonga, Abe E.; Baschant, Ulrike; Rauner, Martina; Moosa, Shaakirah; Marais, Sumari; Kruger, Marlena C.; Coetzee, Magdalena
(Elsevier, 2020-01)
Bone remodelling in a healthy body is in constant balance, maintaining an adaptive and robust skeletal system.
In osteoporosis this balance is disrupted with the rates of osteoclastic bone resorption exceeding osteoblastic
bone ...
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Rantlha, Mpho; Sagar, Travers; Kruger, Marlena C.; Coetzee, Magdalena; Deepak, Vishwa
(Springer, 2017-01)
Bone undergoes continuous remodeling by a coupled action between osteoblasts and osteoclasts. During osteoporosis, osteoclast activity is often elevated leading to increased bone destruction. Hence, osteoclasts are deemed ...
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Sagar, Travers; Rantlha, Mpho; Kruger, Marlena C.; Coetzee, Magdalena; Deepak, Vishwa
(Springer, 2016-10)
Elevated bone loss induced by osteoclasts is a critical and most commonly observed pathological complication during osteolytic diseases such as osteoporosis. Hence, attenuation of osteoclast formation or function is a ...