Browsing by UP Author "Ker, James A."

Browsing by UP Author "Ker, James A."

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  • The accessory papillary muscle with inferior J-waves---peculiarity or hidden danger? 
    Ker, James A.; Du Toit, Lorraine (BioMed Central, 2009-10)
    Originally described in 1953, today the so-called J-wave is the source of much controversy. As a marker of so-called "early repolarization", this variant has been regarded as a totally benign variant since the 1960's. ...
  • ACE hypertension treatment 
    Ker, James A. (Media 24, 2015-04)
    Abundant evidence from randomised controlled trials has documented that antihypertensive drug treatment is of benefit in reducing cardiovascular (CV) events in people with hypertension.
  • Adverse effects of biologic anti-inflammatory agents on the respiratory system : a review 
    Joseph, Darren; Tintinger, Gregory Ronald; Ker, James A.; Pannell, N. (South African Medical Association NPC, 2021)
    The therapy of autoimmune rheumatological conditions has undergone significant changes with the introduction of biologic antiinflammatory agents including cytokine antagonists and agents that interfere with the function ...
  • Angiotensin II type 1 receptor antagonists and their combinations in the treatment of hypertension 
    Ker, James A. (South African Academy of Family Practice/Primary Care, 2012)
    No abstract available.
  • Antihypertensive treatment in the elderly 
    Ker, James A. (South African Academy of Family Practice/Primary Care, 2011-01)
    No abstract available.
  • The arterial duct and the right aortic arch : telescope into the prenatal defective heart 
    Ker, James A. (Springer, 2021-12)
    Progress in the understanding, diagnosis and treatment of congenital cardiovascular anomalies began when dr Helen Taussig founded the pediatric cardiology clinic at the Johns Hopkins Hospital in Baltimore in 1930 and the ...
  • The association between elevated troponin levels and all cause 30 day mortality in critically ill patients seen at an Academic Hospital – a prospective cohort study 
    Joseph, Darren; Ker, James A.; Rheeder, Paul; Ueckermann, Veronica (University of Leicester, 2017-03-07)
    PURPOSES : Elevated cardiac troponins have been shown to be associated with mortality in critical care, but its utility is not well established, especially in the setting of renal failure. This study aimed to examine the ...
  • Autonomic impairment in rheumatoid arthritis 
    Janse van Rensburg, Dina Christina; Ker, James A.; Grant, C.C. (Catharina Cornelia); Fletcher, Lizelle (Blackwell Publishing, 2012-08)
    AIM: To determine if there is a difference between autonomic cardiac control as measured by heart rate variability (HRV) in women with rheumatoid arthritis (RA) compared to a healthy control group. METHODS: The RA group ...
  • Autonomic response to exercise as measured by cardiovascular variability 
    Grant, C.C. (Catharina Cornelia); Ker, James A. (Health and Medical Publishing Group, 2008)
    MOTIVATION: There is growing interest in the use of cardiovascular variability indicators as measures of autonomic activity,even though reported results are not always comparable or as expected. This review aims to determine ...
  • Beta blockers and their combinations in the management of hypertension 
    Ker, James A. (South African Academy of Family Practice/Primary Care, 2012-09)
    Beta blockers have been prescribed for the treatment of primary hypertension for a very long time. Currently, it is doubtful whether this is still a good idea. In fact, many are of the opinion that beta blockers should be ...
  • Bigeminy and the bifid papillary muscle 
    Ker, James A. (BioMed Central, 2010)
    Various structural anomalies of the left ventricular papillary muscles have been observed in recent years. Many of these have been linked to electrocardiographic aberrations. Recently two reports have appeared where the ...
  • The Brody effect induced by premature ventricular complexes in the ovine heart 
    Ker, James A.; Webb, E.C. (Edward Cottington); Van Papendorp, D.H. (Dirk Hermanus), 1949- (Agricultural Research Council, ARC-OVI and the University of Pretoria, 2009-12)
    The QRS response of the electrocardiogram to bleeding has been a source of interest to the physiologist for more than a century. Studies in the dog, cat and chicken have shown a reduction in QRS amplitude in response to ...
  • Broken heart syndrome 
    Ker, James A. (Media 24, 2015)
    Takotsubo was first described in Japan in 1990, but subsequently it was described globally and in 2013 there were 1879 publications on the subject. The main characteristic is transient reversible systolic dysfunction of ...
  • Budget impact analysis of empagliflozin in the treatment of patients with type 2 diabetes with established cardiovascular disease in South Africa 
    De Beer, Janetta Catharina; Snyman, Jacques; Ker, James A.; Miller-Janson, Helen; Stander, Marthinus (Elsevier, 2023-01)
    OBJECTIVES : This study aimed to estimate the budget impact and affordability of empagliflozin added to usual care compared with usual care alone, in a diabetic population with established cardiovascular disease, from a ...
  • Burning issues in acute heart failure management 
    Ker, James A.; Outhoff, Kim (Medpharm Publications, 2019-12)
    In general, heart failure is the end-stage manifestation of cardiovascular disease and is an important and increasing cause of morbidity worldwide. Acute heart failure, whether of new onset or an exacerbation of chronic ...
  • Burning issues in blood pressure control 
    Ker, James A.; Outhoff, Kim (OASIS, 2019-03)
    Globally more than 1 billion people have hypertension and it is predicted that because of ageing populations and increasing sedentary lifestyles, this figure will rise to about 1.5 billion by 2025. Elevated blood pressure ...
  • Burning issues in the prevention of heart failure 
    Ker, James A.; Outhoff, Kim (AOSIS Open Journals, 2019-07)
    Chronic heart failure is common, debilitating, and often the culmination of pervasive cardiovascular insults that systematically undermine the heart’s circulatory capacity and invoke counterproductive neuro-hormonal ...
  • Burning issues in the prevention of heart failure 
    Ker, James A.; Outhoff, Kim (MedPharm Publications, 2020-08)
    Chronic heart failure is common, debilitating, and often the culmination of pervasive cardiovascular insults that systematically undermine the heart’s circulatory capacity and invoke counterproductive neuro-hormonal ...
  • Carboxyhaemoglobin levels in water-pipe and cigarette smokers 
    Theron, Ansa; Schultz, Cedric; Ker, James A.; Falzone, Nadia (Health and Medical Publishing Group, 2010-02)
    Water-pipe smoking is growing in popularity, especially among young people, because of the social nature of the smoking session and the assumption that the effects are less harmful than those of cigarette smoking. It has ...
  • Cardiovascular pharmacogenetics 
    Myburgh, Renier; Hochfeld, Warren Ernst; Dodgen, Tyren Mark; Ker, James A.; Pepper, Michael Sean (Elsevier, 2012-03)
    Human genetic variation in the form of single nucleotide polymorphisms as well as more complex structural variations such as insertions, deletions and copy number variants, is partially responsible for the clinical ...