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Browsing by UP Author "Burger, Divan Aristo"

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Bedaquiline, moxifloxacin, pretomanid, and pyrazinamide during the first 8 weeks of treatment of patients with drug-susceptible or drug-resistant pulmonary tuberculosis : a multicentre, open-label, partially randomised, phase 2b trial

Tweed, Connor D.; Dawson, Rodney; Burger, Divan Aristo; Conradie, Almari; Crook, Angela M.; Mendel, Carl M.; Conradie, Francesca; Diacon, Andreas H.; Ntinginya, Nyanda E.; Everitt, Daniel E.; Haraka, Frederick; Li, Mengchum; Van Niekerk, Christo H.; Okwera, Alphonse; Rassool, Mohammed S.; Reither, Klaus; Sebe, Modulakgotla A.; Staples, Suzanne; Variava, Ebrahim; Spigelman, Melvin (Elsevier, 2019-12)

Please read abstract in the article.
Fourteen-day bactericidal activity, safety, and pharmacokinetics of linezolid in adults with drug-sensitive pulmonary tuberculosis

Diacon, Andreas H.; De Jager, Veronique R.; Dawson, Rodney; Narunsky, Kim; Vanker, Naadira; Burger, Divan Aristo; Everitt, Daniel; Pappas, Frances; Nedelman, Jerry; Mendelf, Carl M. (American Society for Microbiology, 2020-04)

Linezolid is increasingly used for the treatment of tuberculosis resistant to first-line agents, but the most effective dosing strategy is yet unknown. From November 2014 to November 2016, we randomized 114 drug-sensitive ...
A generalized Bayesian nonlinear mixed‐effects regression model for zero‐inflated longitudinal count data in tuberculosis trials

Burger, Divan Aristo; Schall, Robert; Jacobs, Rianne; Chen, Ding-Geng (Din) (Wiley, 2019-07)

In this paper, we investigate Bayesian generalized nonlinear mixed‐effects (NLME) regression models for zero‐inflated longitudinal count data. The methodology is motivated by and applied to colony forming unit (CFU) counts ...
Group-by-treatment interaction effects in comparative bioavailability studies

Schuetz, Helmut; Burger, Divan Aristo; Cobo, Erik; Dubins, David D.; Farkas, Tibor; Labes, Detlew; Lang, Benjamin; Ocana, Jordi; Ring, Arne; Shitova, Anastasia; Stus, Volodymyr; Tomashevskiy, Michael (Springer, 2024-04)

Comparative bioavailability studies often involve multiple groups of subjects for a variety of reasons, such as clinical capacity limitations. This raises questions about the validity of pooling data from these groups in ...
Long-term spatially-replicated data show no physical cost to a benefactor species in a facilitative plant-plant interaction

Raath-Krueger, Morgan J.; Schoeb, Christian; McGeoch, Melodie A.; Burger, Divan Aristo; Strydom, Tanya; Le Roux, Peter Christiaan (Wiley, 2023-04)

Facilitation is an interaction where one species (the benefactor) positively impacts another (the beneficiary). However, the reciprocal effects of beneficiaries on their benefactors are typically only documented using ...
Nonlinear mixed-effects modeling of longitudinal count data: Bayesian inference about median counts based on the marginal zero-inflated discrete Weibull distribution

Burger, Divan Aristo; Lesaffre, Emmanuel (Wiley, 2021-10)

This article proposes a Bayesian regression model for nonlinear zero-inflated longitudinal count data that models the median count as an alternative to the mean count. The nonlinear model generalizes a recently introduced ...
A robust Bayesian mixed effects approach for zero inflated and highly skewed longitudinal count data emanating from the zero inflated discrete Weibull distribution

Burger, Divan Aristo; Schall, Robert; Ferreira, Johannes Theodorus; Chen, Ding-Geng (Din) (Wiley, 2020-04)

This article proposes a Bayesian mixed effects zero inflated discrete Weibull (ZIDW) regression model for zero inflated and highly skewed longitudinal count data, as an alternative to mixed effects regression models that ...
Robust Bayesian nonlinear mixed‐effects modeling of time to positivity in tuberculosis trials

Burger, Divan Aristo; Schall, Robert; Chen, Ding-Geng (Din) (Wiley, 2018-09)

Early phase 2 tuberculosis (TB) trials are conducted to characterize the early bactericidal activity (EBA) of anti‐TB drugs. The EBA of anti‐TB drugs has conventionally been calculated as the rate of decline in colony ...
Robust fit of Bayesian mixed effects regression models with application to colony forming unit count in tuberculosis research

Burger, Divan Aristo; Schall, Robert (Wiley, 2018-02)

Early bactericidal activity of tuberculosis drugs is conventionally assessed using statistical regression modeling of colony forming unit (CFU) counts over time. Typically, most CFU counts deviate little from the regression ...
A robust mixed-effects parametric quantile regression model for continuous proportions : quantifying the constraints to vitality in cushion plants

Burger, Divan Aristo; Van der Merwe, Sean; Lesaffre, Emmanuel; Le Roux, Peter Christiaan; Raath-Kruger, Morgan J. (Wiley, 2023-11)

There is no literature on outlier-robust parametric mixed-effects quantile regression models for continuous proportion data as an alternative to systematically identifying and eliminating outliers. To fill this gap, ...
Virulence and survival of native entomopathogenic nematodes for the management of white grubs in South Africa

Abate, Birhan Addisie; Slippers, Bernard; Wingfield, Michael J.; Conlong, Desmond E.; Burger, Divan Aristo; Hurley, Brett Phillip (Elsevier, 2019-10)

Entomopathogenic nematodes (EPNs) provide a potential alternative to chemical insecticides to control root-feeding pests of agricultural and forestry crops. One of the challenges in using EPNs in these environments is low ...

Browsing by UP Author "Burger, Divan Aristo"

Browsing by UP Author "Burger, Divan Aristo"

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